PAHO/WHO | Pan American Health Organization

New PAHO report reveals that 14 countries in the Americas face health worker shortages

New PAHO report reveals that 14 countries in the Americas face health worker shortages

Cristina Mitchell

30 Apr 2025

New PAHO report reveals that 14 countries in the Americas face health worker shortages

Cristina Mitchell

30 Apr 2025

1 month 1 week ago

PAHO/WHO | Pan American Health Organization

PAHO and UNOPS sign new agreement to promote and strengthen health systems in Latin America and the Caribbean

PAHO and UNOPS sign new agreement to promote and strengthen health systems in Latin America and the Caribbean

Cristina Mitchell

30 Apr 2025

PAHO and UNOPS sign new agreement to promote and strengthen health systems in Latin America and the Caribbean

Cristina Mitchell

30 Apr 2025

1 month 1 week ago

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

USFDA approves AbbVie giant cell arteritis drug Rinvoq in adults

North Chicago, Ill.: AbbVie has received approval from the U.S. Food and Drug Administration (FDA) for RINVOQ (upadacitinib), 15 mg, once daily, for the treatment of adults with giant cell arteritis (GCA).

North Chicago, Ill.: AbbVie has received approval from the U.S. Food and Drug Administration (FDA) for RINVOQ (upadacitinib), 15 mg, once daily, for the treatment of adults with giant cell arteritis (GCA).

This comes after the European Commission recently granted marketing authorization of RINVOQ for the treatment of GCA in adult patients.

The approvals are supported by results of the pivotal Phase 3 SELECT-GCA clinical trial, which met the primary endpoint of sustained remission (46.4% of patients receiving RINVOQ 15 mg in combination with a 26-week steroid taper regimen achieved sustained remission from week 12 to week 52, compared to 29.0% of patients receiving placebo in combination with a 52-week steroid taper regimen; p=0.002).

During the 52-week, placebo-controlled period, the safety profile of RINVOQ was generally consistent with that observed in other approved indications.

"This FDA approval will now provide an alternative treatment option that can offer patients with GCA the possibility of tapering off steroids and achieving sustained remission," said Roopal Thakkar, M.D., executive vice president, research and development, chief scientific officer, AbbVie. "With this new indication for RINVOQ, we are underscoring AbbVie's commitment to exploring how we can identify and address unmet needs for patients with immune-mediated diseases."

GCA is an autoimmune disease that causes inflammation of the temporal and other cranial arteries, the aorta, and other large and medium arteries. If left untreated, the disease can lead to debilitating symptoms and potentially severe outcomes, such as blindness, aortic aneurysm, or stroke. Caucasian women over the age of 50 – most commonly between the ages of 70 and 80 years – have the highest risk of developing GCA. Although women are more likely than men to develop GCA, research suggests that men are more likely to have ocular manifestations with their disease.

"Glucocorticoids remain a mainstay of treatment of GCA but lead to substantial drug-associated toxicities. Additionally, relapse remains common for patients with this disease," said Peter A. Merkel, M.D., MPH, chief of rheumatology at the University of Pennsylvania, Philadelphia, and SELECT-GCA trial investigator. "We now have a new option to treat GCA. The results of this clinical trial show that upadacitinib offers patients the chance to reach sustained remission."

1 month 1 week ago

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Health

Protect your hearing!

EACH YEAR, International Noise Awareness Day (INAD) reminds us of the serious damaging impact excessive noise can have on our hearing health. As we commemorate INAD 2025, the Jamaica Association for the Deaf Hearing Services (JADHS) is committed to...

EACH YEAR, International Noise Awareness Day (INAD) reminds us of the serious damaging impact excessive noise can have on our hearing health. As we commemorate INAD 2025, the Jamaica Association for the Deaf Hearing Services (JADHS) is committed to...

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Jamaican health-tech startup Senzi.Me goes global

WHILE WORKING at Hospital Provincial de Rosario in Argentina, Jamaican Eugenie Addison witnessed firsthand the devastating impact of air pollution on public health. The deadly effects of airborne diseases became painfully personal when she lost...

WHILE WORKING at Hospital Provincial de Rosario in Argentina, Jamaican Eugenie Addison witnessed firsthand the devastating impact of air pollution on public health. The deadly effects of airborne diseases became painfully personal when she lost...

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ANXIETY, STRESS and depression can have a negative impact on your physical health and may even increase your risk for heart disease and stroke. Mental wellness is crucial for overall well-being, impacting how we think, feel, and behave, and...

ANXIETY, STRESS and depression can have a negative impact on your physical health and may even increase your risk for heart disease and stroke. Mental wellness is crucial for overall well-being, impacting how we think, feel, and behave, and...

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EMOTIONAL WELL-BEING is an important part of holistic wellness, as it can impact your outlook on life, your relationships, and your health. Taking care of your emotional well-being matters. When you are emotionally healthy you manage the various...

EMOTIONAL WELL-BEING is an important part of holistic wellness, as it can impact your outlook on life, your relationships, and your health. Taking care of your emotional well-being matters. When you are emotionally healthy you manage the various...

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Health – Dominican Today

Medellín eyes partnership with Dominican Republic to boost health tourism

Santo Domingo.- The Medellín Health City Cluster has expressed interest in establishing partnerships with Dominican health sector organizations and leaders, aiming to enhance medical tourism between both countries. Currently, around 4% of the 11 million tourists visiting the Dominican Republic seek medical services.

Santo Domingo.- The Medellín Health City Cluster has expressed interest in establishing partnerships with Dominican health sector organizations and leaders, aiming to enhance medical tourism between both countries. Currently, around 4% of the 11 million tourists visiting the Dominican Republic seek medical services.

Cluster manager Mónica Sánchez noted that the alliance would promote mutual benefits, including knowledge exchange, shared best practices between health centers, and improved patient care. She highlighted the Dominican Republic’s well-trained medical professionals and visionary leadership as strengths for forming a successful collaboration.

Sánchez emphasized Medellín’s capacity to contribute with its high-complexity health centers and praised the Dominican Association of Health and Wellness Tourism (ADTS), under Dr. Alejandro Cambiaso, for its role in positioning the country as a leader in medical tourism.

1 month 1 week ago

Health, tourism

Healio News

‘First of a new class’: FDA approves upadacitinib to treat giant cell arteritis

The FDA has approved the Janus kinase inhibitor upadacitinib for the treatment of giant cell arteritis in adults, the first such approval in the disease since tocilizumab received the green light in 2017, according to a press release.The decision, allowing adults with GCA to receive 15 mg of upadacitinib (Rinvoq, AbbVie) once daily, represents the debut of a “new class of drugs” for GCA, accord

ing to Kenneth Warrington, MD, a rheumatologist, John F. Finn Minnesota Arthritis Foundation professor of medicine and director of the Vasculitis Clinic at the Mayo Clinic, in Rochester,

1 month 1 week ago

Medscape Medical News Headlines

FDA Okays Upadacitinib for Giant Cell Arteritis

This is the first and only oral JAK inhibitor indicated for giant cell arteritis, according to the manufacturer AbbVie. Medscape Medical News

This is the first and only oral JAK inhibitor indicated for giant cell arteritis, according to the manufacturer AbbVie. Medscape Medical News

1 month 1 week ago

Rheumatology, News Alert

Health – Dominican Today

ONPECO backs nutritional labeling policy

Santo Domingo.- The National Observatory for Consumer Protection (ONPECO) has voiced strong support for a Ministry of Public Health resolution that promotes the implementation of Front-of-Pack Nutritional Warning Labels (EFAN) in the Dominican Republic.

Santo Domingo.- The National Observatory for Consumer Protection (ONPECO) has voiced strong support for a Ministry of Public Health resolution that promotes the implementation of Front-of-Pack Nutritional Warning Labels (EFAN) in the Dominican Republic. According to ONPECO, this measure is essential to uphold citizens’ right to know what they are consuming and to make informed choices that may reduce the risk of non-communicable diseases.

The organization stressed that EFAN does not require companies to change product formulas, but simply aims to provide clear information so consumers can decide for themselves. ONPECO criticized the resistance to the initiative, noting that it mirrors successful policies in other Latin American countries like Mexico, Chile, and Argentina, where no economic or employment impacts have been recorded.

Citing a study by the Healthy America Coalition (CLAS), ONPECO addressed and dismissed myths promoted by some industries—such as claims that WHO/PAHO nutrient standards are too strict or that EFAN harms the economy. It reaffirmed that the WHO guidelines are science-based and that transparent labeling aligns with global standards like ISO 26000 on corporate responsibility and the OECD’s calls for clear food information.

Finally, ONPECO urged broad dissemination of the resolution, reiterating that the Dominican State is constitutionally obligated to protect public health and ensure consumers’ right to accurate product information.

1 month 1 week ago

Health

Health Archives - Barbados Today

Lack of early autism screening a major concern, says association head

The lack of early autism screening in Barbados remains a major concern, according to the President of the Barbados Autism Association, Frank Johnson, who hopes that public events like the Autism Heroes Walk will help raise awareness and drive change.

“The main challenge is getting screening for the children early enough. A child should really be screened at three years old. It’s a little difficult screening before three, but if a child has missed developmental milestones . . . you really should become aware that there may be a challenge involved,” Johnson said on Monday, as over 200 men, women, and children took part in the annual Autism Heroes Fun and Wellness Walk and Cool Down Fair.

Beyond early diagnosis, Johnson pointed to other issues, including the absence of reliable national data on autism.

“We don’t have strict numbers here in Barbados,” he explained. “There has not been what I call a census taken of the exact number of children with this disability.

“The last national census that was done… it didn’t focus on a particular developmental challenge, which I think it should do.”

He also highlighted a critical shortage of trained professionals, saying: “We do need more specialists. We need more occupational therapists, and speech therapists or speech and pathology specialists. They do a fantastic job, but they are oversubscribed.”

However, for many families, the cost of private screening and therapy remains a heavy burden.

“A lot of our parents have to pay privately for consultants to carry out screening and testing . . . . Getting it done privately is expensive . . . but as I say to parents out there: think of it as an investment in your child’s future.

“A lot of young parents . . . have no idea what they’re up against . . . except that they know there is something wrong. They go to their GP or the polyclinic and report that their child is missing the developmental milestones.”

To address these challenges, Johnson said the association is working on forming partnerships that would make screening more affordable.

“In the near future, possibly working with insurance companies to provide support grants to parents who cannot afford the intervention. If we can swing that towards those groups in the next couple of years, we will be making fantastic strides.”

In addition to those efforts, the association is preparing to expand its physical presence. A new headquarters in the Garrison area is currently being renovated, which Johnson hopes will become a hub for affordable, accessible support and therapy.

“We are just about to finish our renovated building, which has been granted to us by the government,” he said. “We’ve taken out a lease for ten years, with a renewable ten years, just around the corner from the Barbados Council for the Disabled.

“We hope to go into partnership with speech therapists and occupational therapists to be able to offer subsidised programmes. We do see ourselves as providing many different answers . . . for all income brackets.”

He added that the association is launching new initiatives to support those families emotionally and mentally. (LG)

 

The post Lack of early autism screening a major concern, says association head appeared first on Barbados Today.

1 month 1 week ago

Health, Local News

PAHO/WHO | Pan American Health Organization

Disease elimination takes center stage at Vaccination Week in the Americas launch

Disease elimination takes center stage at Vaccination Week in the Americas launch

Cristina Mitchell

28 Apr 2025

Disease elimination takes center stage at Vaccination Week in the Americas launch

Cristina Mitchell

28 Apr 2025

1 month 1 week ago

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Low-Dose Sirolimus as Effective as High-Dose for Kaposiform Hemangioendothelioma Treatment, suggests study

Researchers have found in new research that low-dose sirolimus is noninferior to high-dose sirolimus in the treatment of Kaposiform Hemangioendothelioma (KHE), suggesting that lower doses may be a viable treatment option.

It remains unknown whether low-dose sirolimus can replace high-dose sirolimus for the treatment of kaposiform hemangioendothelioma (KHE) without the Kasabach–Merritt phenomenon (KMP). A study was done to evaluate the noninferiority and safety of low-dose versus high-dose sirolimus in Kaposiform Hemangioendothelioma patients.

This randomized, multicenter, open-label, noninferiority trial was conducted from February 2021 to August 2022. Participants received either a low-dose sirolimus regimen (blood trough concentration 5-8 ng/mL) or a high-dose sirolimus regimen (blood trough concentration 10-15 ng/mL). The primary endpoint was the difference in the proportion of patients between groups who achieved an objective response, defined as a ≥20% reduction in Kaposiform Hemangioendothelioma volume at month 12.

Results: In this study, 39 were in the low-dose group, and 40 were in the high-dose group. At 1 year of treatment, 90.0% in the high-dose group and 89.7% in the low-dose group achieved an objective response (difference, 0.3%; 95% confidence interval -13.1 to 13.6). The incidences of total adverse events (AEs) and serious adverse events were similar between the two groups, but respiratory, skin and mucosal adverse events were less common in the low-dose group.

Low-dose sirolimus is noninferior to high-dose sirolimus in treating Kaposiform Hemangioendothelioma.

Reference:

Efficacy and Safety of High- vs Low-Dose Sirolimus in Patients with Kaposiform Hemangioendothelioma: A Randomized Clinical Trial Zhou, Jiangyuan et al. Journal of the American Academy of Dermatology, Volume 0, Issue 0

1 month 1 week ago

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Health | NOW Grenada

PM on first official visit to Bolivarian Republic of Venezuela

“During the official visit, Prime Minister Mitchell is scheduled to hold high-level discussions with President Nicolas Maduro Moros to discuss key areas of interest”

1 month 1 week ago

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KFF Health News

When Hospitals Ditch Medicare Advantage Plans, Thousands of Members Get To Leave, Too

For several years, Fred Neary had been seeing five doctors at the Baylor Scott & White Health system, whose 52 hospitals serve central and northern Texas, including Neary’s home in Dallas. But in October, his Humana Medicare Advantage plan — an alternative to government-run Medicare — warned that Baylor and the insurer were fighting over a new contract.

If they couldn’t reach an agreement, he’d have to find new doctors or new health insurance.

“All my medical information is with Baylor Scott & White,” said Neary, 87, who retired from a career in financial services. His doctors are a five-minute drive from his house. “After so many years, starting over with that many new doctor relationships didn’t feel like an option.”

After several anxious weeks, Neary learned Humana and Baylor were parting ways as of this year, and he was forced to choose between the two. Because the breakup happened during the annual fall enrollment period for Medicare Advantage, he was able to pick a new Advantage plan with coverage starting Jan. 1, a day after his Humana plan ended.

Other Advantage members who lose providers are not as lucky. Although disputes between health systems and insurers happen all the time, members are usually locked into their plans for the year and restricted to a network of providers, even if that network shrinks. Unless members qualify for what’s called a special enrollment period, switching plans or returning to traditional Medicare is allowed only at year’s end, with new coverage starting in January.

But in the past 15 months, the Centers for Medicare & Medicaid Services, which oversees the Medicare Advantage program, has quietly offered roughly three-month special enrollment periods allowing thousands of Advantage members in at least 13 states to change plans. They were also allowed to leave Advantage plans entirely and choose traditional Medicare coverage without penalty, regardless of when they lost their providers. But even when CMS lets Advantage members leave a plan that lost a key provider, insurers can still enroll new members without telling them the network has shrunk.

At least 41 hospital systems have dropped out of 62 Advantage plans serving all or parts of 25 states since July, according to Becker’s Hospital Review. Over the past two years, separations between Advantage plans and health systems have tripled, said FTI Consulting, which tracks reports of the disputes.

CMS spokesperson Catherine Howden said it is “a routine occurrence” for the agency to determine that provider network changes trigger a special enrollment period for their members. “It has happened many times in the past, though we have seen an uptick in recent years.”

Still, CMS would not identify plans whose members were allowed to disenroll after losing health providers. The agency also would not say whether the plans violated federal provider network rules intended to ensure that Medicare Advantage members have sufficient providers within certain distances and travel times.

The secrecy around when and how Advantage members can escape plans after their doctors and hospitals drop out worries Sen. Ron Wyden of Oregon, the senior Democrat on the Senate Finance Committee, which oversees CMS.

“Seniors enrolled in Medicare Advantage plans deserve to know they can change their plan when their local doctor or hospital exits the plan due to profit-driven business practices,” Wyden said.

The increase in insurer-provider breakups isn’t surprising, given the growing popularity of Medicare Advantage. The plans attracted about 54% of the 61.2 million people who had both Medicare Parts A and B and were eligible to sign up for Medicare Advantage in 2024, according to KFF, a health information nonprofit that includes KFF Health News.

The plans can offer supplemental benefits unavailable from traditional Medicare because the federal government pays insurers about 20% more per member than traditional Medicare per-member costs, according to the Medicare Payment Advisory Commission, which advises Congress. The extra spending, which some lawmakers call wasteful, will total about $84 billion in 2025, MedPAC estimates. While traditional Medicare does not offer the additional benefits Advantage plans advertise, it does not limit beneficiaries’ choice of providers. They can go to any doctor or hospital that accepts Medicare, as nearly all do.

Sanford Health, the largest rural health system in the U.S., serving parts of seven states from South Dakota to Michigan, decided to leave a Humana Medicare Advantage plan last year that covered 15,000 of its patients. “It’s not so much about the finances or administrative burden, although those are real concerns,” said Nick Olson, Sanford Health’s chief financial officer. “The most important thing for us is the fact that coverage denials and prior authorization delays impact the care a patient receives, and that’s unacceptable.”

The National Association of Insurance Commissioners, representing insurance regulators from every state, Puerto Rico, and the District of Columbia, has appealed to CMS to help Advantage members.

“State regulators in several states are seeing hospitals and crucial provider groups making decisions to no longer contract with any MA plans, which can leave enrollees without ready access to care,” the group wrote in September. “Lack of CMS guidance could result in unnecessary financial or medical injury to America’s seniors.”

The commissioners appealed again last month to Health and Human Services Secretary Robert F. Kennedy Jr. “Significant network changes trigger important rights for beneficiaries, and they should receive clear notice of their rights and have access to counseling to help them make appropriate choices,” they wrote.

The insurance commissioners asked CMS to consider offering a special enrollment period for all Advantage members who lose the same major provider, instead of placing the burden on individuals to find help on their own. No matter what time of year, members would be able to change plans or enroll in government-run Medicare.

Advantage members granted this special enrollment period who choose traditional Medicare get a bonus: If they want to purchase a Medigap policy — supplemental insurance that helps cover Medicare’s considerable out-of-pocket costs — insurers can’t turn them away or charge them more because of preexisting health conditions.

Those potential extra costs have long been a deterrent for people who want to leave Medicare Advantage for traditional Medicare.

“People are being trapped in Medicare Advantage because they can’t get a Medigap plan,” said Bonnie Burns, a training and policy specialist at California Health Advocates, a nonprofit watchdog that helps seniors navigate Medicare.

Guaranteed access to Medigap coverage is especially important when providers drop out of all Advantage plans. Only four states — Connecticut, Massachusetts, Maine, and New York — offer that guarantee to anyone who wants to reenroll in Medicare.

But some hospital systems, including Great Plains Health in North Platte, Nebraska, are so frustrated by Advantage plans that they won’t participate in any of them.

It had the same problems with delays and denials of coverage as other providers, but one incident stands out for CEO Ivan Mitchell: A patient too sick to go home had to stay in the hospital an extra six weeks because her plan wouldn’t cover care in a rehabilitation facility.

With traditional Medicare the only option this year for Great Plains Health patients, Nebraska insurance commissioner Eric Dunning asked for a special enrollment period with guaranteed Medigap access for some 1,200 beneficiaries. After six months, CMS agreed.

Once Delaware’s insurance commissioner contacted CMS about the Bayhealth medical system dropping out of a Cigna Advantage plan, members received a special enrollment period starting in January.

Maine’s congressional delegation pushed for an enrollment period for nearly 4,000 patients of Northern Light Health after the 10-hospital system dropped out of a Humana Advantage plan last year.

“Our constituents have told us that they are anticipating serious challenges, ranging from worries about substantial changes to cost-sharing rates to concerns about maintaining care with current providers,” the delegation told CMS.

CMS granted the request to ensure “that MA enrollees have access to medically necessary care,” then-CMS Administrator Chiquita Brooks-LaSure wrote to Sen. Angus King (I-Maine).

Minnesota insurance officials appealed to CMS on behalf of some 75,000 members of Aetna, Humana, and UnitedHealthcare Advantage plans after six health systems announced last year they would leave the plans in 2025. So many provider changes caused “tremendous problems,” said Kelli Jo Greiner, director of the Minnesota State Health Insurance Assistance Program, known as a SHIP, at the Minnesota Board on Aging. SHIP counselors across the country provide Medicare beneficiaries free help choosing and using Medicare drug and Advantage plans.

Providers serving about 15,000 of Minnesota’s Advantage members ultimately agreed to stay in the insurers’ networks. CMS decided 14,000 Humana members qualified for a network-change special enrollment period.

The remaining 46,000 people — Aetna and UnitedHealthcare Advantage members — who lost access to four health systems were not eligible for the special enrollment period. CMS decided their plans still had enough other providers to care for them.

KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF—an independent source of health policy research, polling, and journalism. Learn more about KFF.

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Aging, Health Care Costs, Health Industry, Insurance, Medicare, Rural Health, CMS, Connecticut, Delaware, Hospitals, Maine, Massachusetts, Medicare Advantage, Michigan, Minnesota, Nebraska, New York, South Dakota, texas

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