Medical News, Health News Latest, Medical News Today - Medical Dialogues |

AbbVie to acquire ImmunoGen, including its flagship cancer therapy Elahere

North Chicago, Ill.: AbbVie Inc. and ImmunoGen, Inc. have announced a definitive agreement under which AbbVie will acquire ImmunoGen, and its flagship cancer therapy ELAHERE (mirvetuximab soravtansine-gynx), a first-in-class antibody-drug conjugate (ADC) approved for platinum-resistant ovarian cancer (PROC).

The acquisition accelerates AbbVie's commercial and clinical presence in the solid tumor space. Additionally, ImmunoGen's follow-on pipeline of promising next-generation ADCs further complements AbbVie's ADC platform and existing programs.

Under the terms of the transaction, AbbVie will acquire all outstanding shares of ImmunoGen for $31.26 per share in cash. The transaction values ImmunoGen at a total equity value of approximately $10.1 billion. The boards of directors of both companies have approved the transaction. This transaction is expected to close in the middle of 2024, subject to ImmunoGen shareholder approval, regulatory approvals, and other customary closing conditions.

"The acquisition of ImmunoGen demonstrates our commitment to deliver on our long-term growth strategy and enables AbbVie to further diversify our oncology pipeline across solid tumors and hematologic malignancies," said Richard A. Gonzalez, chairman and chief executive officer, AbbVie. "Together, AbbVie and ImmunoGen have the potential to transform the standard of care for people living with cancer."

ImmunoGen's oncology portfolio has the potential to help drive long-term revenue growth for AbbVie's oncology franchise. Ovarian cancer is the leading cause of death from gynecological cancers in the U.S. ELAHERE is the first targeted medicine to show meaningful survival benefit in PROC. As a fast-growing solid tumor therapy, ELAHERE provides AbbVie with a potential multi-billion-dollar on-market medicine with expansion opportunities in earlier lines of therapy and larger segments of the ovarian cancer market.

"With global commercial infrastructure and deep clinical and regulatory expertise, AbbVie is the right company to accelerate geographic and label expansion, and realize the full potential of ELAHERE as the first and only ADC approved in ovarian cancer," said Mark Enyedy, president and chief executive officer, ImmunoGen. "The addition of ImmunoGen's pipeline, platform, and expertise to AbbVie's oncology portfolio is an exciting opportunity for the combined companies to advance innovation in ADCs. This transaction is the culmination of our 40-year commitment to develop and deliver the next-generation of ADCs and more good days for people living with cancer."

ELAHERE is a first-in-class ADC targeting folate receptor alpha (FRα) with a maytansinoid payload DM4, a potent tubulin inhibitor designed to kill the targeted cancer cells. ELAHERE received U.S. Food and Drug Administration (FDA) accelerated approval in 2022 for the treatment of adult patients with FRα positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, who have received one to three prior systemic treatment regimens. The positive Phase 3 results from the MIRASOL confirmatory trial will support a Marketing Authorization Application (MAA) to the European Union and a supplemental Biologic License Application (sBLA) submission to the U.S. FDA in order to gain full approval. Ongoing clinical development programs are underway to expand into earlier lines of therapy and enter other large patient segments of the ovarian market over the next 5-10 years.

ImmunoGen's follow-on pipeline of promising next-generation ADCs expands AbbVie's growing oncology pipeline of potentially transformative programs across multiple different solid tumors and hematologic malignancies. ImmunoGen's Phase 1 asset, IMGN-151, is a next-generation anti-FRα ADC for ovarian cancer with the potential for expansion into other solid tumor indications. Pivekimab sunirine, currently in Phase 2, is an anti-CD123 ADC targeting blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare blood cancer, which was granted FDA breakthrough therapy designation for the treatment of relapsed/refractory BPDCN.

AbbVie will acquire all outstanding ImmunoGen common stock for $31.26 per share in cash. The proposed transaction is subject to customary closing conditions, including receipt of regulatory approvals and approval by ImmunoGen stockholders. The proposed transaction is expected to be accretive to diluted earnings per share (EPS) beginning in 2027.

Read also: Abbvie executive Patrick Horber appointed as Novartis's President, International

1 year 6 months ago

News,Oncology,Oncology News,Industry,Pharma News,Latest Industry News

News Archives - Healthy Caribbean Coalition

HCC Statement on the Passing of Dr. Carissa F. Etienne PAHO/WHO Director Emeritus

Photo copyright PAHO

The President, Vice President, Board of Directors, member organizations and staff of the Healthy Caribbean Coalition (HCC) are shocked and deeply saddened by the news of the passing of PAHO Director Emeritus and our very own Caribbean public health champion Dr. Carissa Etienne.

Photo copyright PAHO

The President, Vice President, Board of Directors, member organizations and staff of the Healthy Caribbean Coalition (HCC) are shocked and deeply saddened by the news of the passing of PAHO Director Emeritus and our very own Caribbean public health champion Dr. Carissa Etienne.

Dr Etienne, a Dominican national and a graduate of the University of the West Indies, had a distinguished career in the field of health, both at the national and international levels. She was a champion of universal health coverage, a leader in the fight against non-communicable diseases (NCDs) and COVID-19 in the Region, and oversaw the elimination of several communicable diseases, such as measles, rubella, and congenital rubella syndrome, in the Americas. Dr Etienne was an honorary Vice-President of the American Public Health Association and had many other affiliations and awards.

The HCC family expresses our deepest condolences to Dr Etienne’s family, friends, colleagues, and the entire health community in the Caribbean and beyond. Dr. Etienne was a visionary and a mentor who inspired many with her passion, dedication, and wisdom. She was a friend and a partner of the HCC, and we are grateful for her support and collaboration over the years. She will be greatly missed and fondly remembered by all of us who had the privilege of working with her or learning from her.

The HCC is a civil society alliance established to combat NCDs and their associated risk factors and conditions in the Caribbean. We share Dr. Etienne’s vision of a healthier and more equitable Region, and we will continue to work towards achieving it in her honor and memory. We join PAHO, the WHO and the Caribbean in celebrating her life and legacy, and hope that her example will inspire the next generation of health leaders in the Caribbean and beyond. May she rest in peace.

The post HCC Statement on the Passing of Dr. Carissa F. Etienne PAHO/WHO Director Emeritus appeared first on Healthy Caribbean Coalition.

1 year 6 months ago

Latest, News, Open Letters & Statements

Health Archives - Barbados Today

Four parishes to be fogged this week

Emphasis will be placed on four parishes this week when the Vector Control Unit of the Ministry of Health and Wellness continues its fogging exercise.

Emphasis will be placed on four parishes this week when the Vector Control Unit of the Ministry of Health and Wellness continues its fogging exercise.

The programme starts in St Michael on Monday, December 4, with fogging at Lower Burney, Cutting Road, Mount Friendship Road and the environs.

On Tuesday, December 5, the team will journey to St Joseph, where Horse Hill, Orange Cottage, Vaughns Road 1, 2 and 3, Easy Hall, Bowling Alley Hill and the environs will be sprayed.

The following day, Wednesday December 6, attention will shift to St Philip where fogging will occur at Hill Drive, Apple Hall, Bottom Bay Road, Terrace Drive, Bottom Drive, Bay Drive, Ocean Drive and the environs.

On Thursday, December 7, the team will spray the St James districts of Jamestown Park, First and Second Street, Cherry Ave., Frangipani Row, Carnation Row, Orchid Row, Oleander Row and environs.

Fogging culminates on Friday, December 8, with a return to St Michael. The areas to be visited are Bank Hall, Dash Gap with Avenues, Quarry Road, Industry Road, Kew Road and the surrounding districts.

Fogging takes place from 4:30 to 8:30 p.m., daily.

Householders are asked to assist in the control of the aedes aegypti mosquito and are reminded to open their windows and doors to allow the spray to enter. Persons with respiratory problems are asked to protect themselves from inhaling the spray.

Pedestrians and motorists should proceed with caution when encountering fogging operations on the street and parents are instructed to prohibit children from playing in the fog or running behind the fogging machine.

Members of the public are advised that the completion of scheduled fogging activities may be affected by events beyond the Unit’s control.  In such circumstances, the Unit will return to communities affected as soon as possible.

(PR)

The post Four parishes to be fogged this week appeared first on Barbados Today.

1 year 6 months ago

A Slider, Environment, Health, Local News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Prone Positioning Does Not Impact ECMO Weaning Time in Covid patients with Severe ARDS: JAMA

A randomized clinical trial by Matthieu Schmidt and team investigated the impact of prone positioning on patients with severe acute respiratory distress syndrome (ARDS) undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO). The findings of the study were published in the Journal of American Medical Association.

The trial was conducted from March 3, 2021, to December 7, 2021, aimed to discern whether prone positioning would decrease the time to successful ECMO weaning. The study involved 170 patients with severe ARDS across 14 intensive care units in France, with a median age of 51 years, of which 35% were women. Notably, 94% of patients had ARDS related to COVID-19. Patients were randomized into a group undergoing prone positioning (at least 4 sessions of 16 hours), and the other in a supine position.

Within 60 days of enrollment, the results of the study indicated that there was no significant difference in the time to successful ECMO weaning between the two groups. In the prone ECMO group, 44% of patients experienced successful ECMO weaning when compared to 44% in the supine ECMO group. Moreover, within 90 days, no significant disparities were observed in ECMO duration, length of stay in ICU, or 90-day mortality rates.

Although prone positioning showed promise in improving outcomes for patients with severe ARDS, the findings suggest that its application did not significantly reduce the time to successful ECMO weaning in this particular patient population. 

The findings underscore the complexity of managing severe respiratory conditions and the importance of evidence-based approaches in critical care. As discussions on respiratory care continue to evolve, research endeavors like this shed light on the nuances of treatment strategies, helping refine protocols for better patient outcomes in intensive care settings.

Source:

Schmidt, M., Hajage, D., Lebreton, G., Dres, M., Guervilly, C., Richard, J. C., Sonneville, R., Winiszewski, H., Muller, G., Beduneau, G., Mercier, E., Roze, H., Lesouhaitier, M., Terzi, N., Thille, A. W., Laurent, I., Kimmoun, A., Combes, A., … Luyt, C. E. (2023). Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS. In JAMA. American Medical Association (AMA). https://doi.org/10.1001/jama.2023.24491

1 year 6 months ago

Top Medical News,Critical Care,Critical Care News

Jamaica Observer

A deep dive into Jamaican men's health

MEN are, for the most part, seen as the physically stronger gender because they are usually bigger and have more muscle than women. This belief extends to health and oftentimes a man/boy may be thought of as weak or inadequate should he mention illness, and so is encouraged to cover up 'minor aches and pains' and keep it moving.

This among other attitudes and values has resulted in men having poor self-care, poorer health practices and ultimately presenting later or not at all for health issues which ultimately leads to poorer outcomes. Believe it or not, men are more likely to experience chronic medical conditions due to different lifestyle and social factors including smoking, alcohol, substance abuse, lack of exercise, stress, conflict resolution and an unhealthy diet.

Further, amidst the tropical beauty of this Caribbean haven, the pursuit of well-being takes centre stage. Join me on this journey as we delve briefly into the distinctive health landscape tailored for Jamaican men.

Prostate health

Now, let's turn our focus to the prostate, a seemingly small gland that holds considerable influence over men's health. Recently at a talk including both sexes in the audience on men's health two questions were posed: When is Breast Cancer Awareness Month and when is Prostate Cancer Awareness Month? Everyone knew that breast cancer month was October but considerably less were even aware that there was a Prostate Cancer Awareness Month (which is September). Prostate cancer is the commonest cancer and cause of cancer-related deaths in Jamaica even more so than breast cancer. So I certainly applaud and endorse all the necessary attention and light that has been shed on breast health and cancer awareness and endorse that even more should be done; but prostate health is still woefully lacking and requires our attention to improve health outcomes. This prevalent concern prompts us to adopt a proactive stance through regular check-ups (an inexhaustible reminder that this is recommended starting at 40 years old). These examinations extend beyond mere screenings; they evolve into collaborative consultations. Conversations delve into individual risk factors, family medical history, and lifestyle intricacies. The goal is not just to detect potential problems but to cultivate a partnership, wherein patients actively contribute to their well-being journey. Embracing a healthy lifestyle becomes pivotal in nurturing optimal prostate health. Imagine it as creating a fertile ground for this vital gland to thrive — a balanced diet, replete with fruits and vegetables, coupled with a routine of regular exercise. This regimen isn't just about maintaining physical health; it's about offering the prostate a supportive environment for long-term well-being.

Sexual health

Transitioning to the realm of sexual health, we navigate through cultural nuances that sometimes obscure these essential discussions. Despite the intricacies, creating a safe space for open dialogue is imperative. Beyond the realm of treatments, our conversations span preventive measures and lifestyle choices that positively impact sexual health. Consider it as fostering an environment akin to a heart-to-heart chat, where destigmatising discussions empowers men to comfortably share concerns. The focus broadens beyond specific conditions like erectile function to encompass the entire spectrum of sexual well-being. By addressing these aspects, we pave the way for empowered conversations that contribute significantly to a man's overall health.

Cardiovascular health

Now, let's shift our focus to the heart of the matter — cardiovascular health. Beyond the realm of prescriptions, we embark on a journey towards a heart-healthy lifestyle. These discussions aren't mere directives but a collaborative exploration of choices that transcend medication. Emphasis is placed on the significance of a balanced diet, steering away from saturated fats and sodium, while embracing heart-healthy foods such as fruits, vegetables, and whole grains. Regular exercise is not just a recommendation; it's an integral part of the prescription for well-being. It's about empowering individuals to take charge of their cardiovascular health for the long haul. Picture it as a daily commitment to shower your heart with care and affection, fostering a relationship with your cardiovascular health that extends beyond medical interventions.

Mental health

It's wrong to assume that men don't struggle simply because they are expected to be strong and silent. Media and television more often portray crying men as something to be scoffed at. Mocking this healthy, human emotional release only serves to discourage men in talking to others about their difficulties and seeking the necessary help. Recent suicide rates in Jamaica show that men are four times (and as high as nine times more in 2006) more likely to do so than women. This is no doubt related to less males seeking medical care and more so for psychiatric disorders because of cultural undertones and the expectation that a man should not show weakness. There is an amusing social media clip currently that says 'man fi be a man and not no weak jelly back'. As much as I believe in the man being the protector and provider of the family, he shouldn't have to feel that it is a sign of weakness to open up, display emotions and seek help for depression instead of keeping it in and engaging in unhealthy vices in some cases such as substance abuse.

Venturing into the often underestimated realm of mental health, we recognise the intricate connection between mental and urological well-being. Stress, anxiety, and psychological factors aren't isolated concerns; they are threads intricately woven into the fabric of holistic health. In our discussions, we traverse beyond medications and treatments, diving deep into stress management techniques, coping strategies, and the pivotal role of seeking support when needed. Mental health is not a standalone entity but an integral part of a man's overall well-being. Picture it as acknowledging the see-saw effect — when one side is off-balance, the other is inevitably affected. This holistic approach embraces the interconnected nature of mental and urological health, creating a symbiotic relationship that significantly contributes to overall well-being.

Cultural sensitivity

In Jamaica's vibrant cultural tapestry, health care is not a one-size-fits-all solution; it's a dance that resonates with the community. As a urologist, understanding and respecting this cultural richness is fundamental. Recommendations aren't imposed but tailored to align seamlessly with the local ethos. Trust and connection become the cornerstones, ensuring that health advice transcends mere medical guidance to become a relatable and effective part of the community's well-being journey. This dance between health care and culture is more than just acknowledging differences; it's about celebrating diversity and fostering an environment where health recommendations feel not only relevant but deeply connected to the fabric of Jamaican life.

Collaborative efforts

Concluding our exploration, let's shine a spotlight on the collaborative efforts essential in the realm of men's health. It's not a solitary pursuit but a communal endeavour that involves doctors, community leaders, and every individual. This collaboration is akin to orchestrating a health festival, where collective efforts spread the message of well-being far and wide. It's about uniting to organise health events, disseminate crucial information, and create a ripple effect of awareness and care. In this collaborative tapestry, everyone plays a unique part, ensuring that health is not just a personal endeavour but a shared celebration of good health and well-being for all.

Conclusion

In this deep dive into men's health in Jamaica, the narrative extends beyond the clinical to embrace a holistic approach that resonates with the unique spirit of the island. It's not merely about treatments; it's about fostering a culture of understanding, openness, and proactive care. Here's to a healthier and happier future for the men of this beautiful island!

Dr Jeremy Thomas is a consultant urologist. He works privately in Montego Bay, Savanna-la-Mar and Kingston, and publicly at Cornwall Regional Hospital. He may be contacted on Facebook and Instagram: @jthomasurology or by e-mail: jthomasurology@gmail.com

1 year 6 months ago

Jamaica Observer

Sandals Foundation teams up with Hospiten to continue fight against breast cancer

MONTEGO BAY, St James — In a concerted effort to continue the fight against breast cancer beyond the designated awareness month of October, Sandals Foundation has joined forces with Hospiten Montego Bay to provide complimentary mammograms to women throughout the region.

This collaboration forms part of Sandals Foundation's annual breast cancer campaign, emphasising the importance of early detection and treatment.

The community response to the initiative has been overwhelmingly positive, with many women expressing gratitude for the opportunity to prioritise their health without the financial strain.

Breast cancer remains one of the most prevalent forms of cancer among women globally, and routine mammograms play a crucial role in identifying potential abnormalities before symptoms manifest. Despite the proven effectiveness of mammography, financial constraints often hinder women from scheduling these screenings regularly.

Thirty women joined the Sandals Montego Bay public relations team at Hospiten over three consecutive days, to receive the possibly life-saving procedure. Testimonials from participants such as Ann-Marie Blake-Reid and Roslyn Smith highlighted their appreciation for the initiative.

"Today I am feeling very happy, very thankful to the Sandals Foundation for allowing us to do our mammograms at Hospiten. This initiative means so much to me because I have wanted to do it since last year but, to be honest, I couldn't afford it so when I saw this initiative I was so excited," noted enthused testee Ann-Marie Blake-Reid from the Whitehouse community.

Blake-Reid continued, "Not only did we receive complimentary mammograms but also catering from the resort — and they even went as far as providing transportation for myself and all the ladies to and from Hospiten. To say we were well taken care of would be a gross understatement. This is something I hope women like me can benefit from for many years to come."

Experienced testee Roslyn Smith from the Rose Mount community sang a similar tune, also speaking highly of her experience by sharing, " The mammograms I've done in the past pale in experience to this one. More often than not it is a vulnerable and sometimes intimidating moment for a woman but, oddly, I can say this experience has been quite fun.

"A mammogram can run you up in the thousands, depending on where you get it done, so I am grateful to the Sandals Foundation for offsetting that cost while providing such a relaxing and accommodating experience with the staff at Hospiten. It has been great, to say the least," said Smith.

Health-care providers at Hospiten involved in the programme have also stressed the importance of education and awareness about breast health. Alongside offering free mammograms, informational sessions and resources are being provided to help women better understand the importance of regular screenings, risk factors, and healthy lifestyle choices that can contribute to overall breast health.

Hospiten Radiography Supervisor Racquel Dickenson-McDonald spoke candidly to the women before their screening and commended them. "Taking charge of your health is something you all should be proud of. Early detection can make a world of difference when it comes to breast cancer and the treatment of it, if necessary," she noted.

McDonald also shared that there are many misconceptions surrounding mammography, many of which paint the procedure as something that is nothing like the reality. "I even joked with one of the ladies here today who said she was so nervous but found it relaxing," she said. "I love initiatives like these with the Sandals Foundation because not only does it allow for women to know their status but it also gives us, as health-care professionals, an opportunity to reach out to our community members and debunk a lot of myths in the process — and hopefully the women here today can take that back with them."

As the fight against breast cancer continues Sandals Foundation has pledged its support for more initiatives like this in the future.

Executive director of Sandals Foundation Heidi Clarke spoke of the future of the early detection campaign by sharing, "As long as there are women needing help receiving mammograms, the Sandals Foundation will do its part to increase access. This is a fundamental part of our mandate to [enhance] community development — supporting the health and well-being of residents all year long."

1 year 6 months ago

Health – Demerara Waves Online News- Guyana

Late PAHO Director Dr Carissa Etienne hailed as “friend” of Guyana’s public health system

Guyana’s Minister of Health, Dr Frank Anthony and the Ministry of Health on Saturday hailed the contributions of former Director of the Pan American Health Organization (PAHO) and World Health Organization (WHO) Regional Director for the Americas, Dr Carissa Etienne who passed away suddenly on Friday. “The Minister of Health, Dr Frank Anthony is saddened ...

Guyana’s Minister of Health, Dr Frank Anthony and the Ministry of Health on Saturday hailed the contributions of former Director of the Pan American Health Organization (PAHO) and World Health Organization (WHO) Regional Director for the Americas, Dr Carissa Etienne who passed away suddenly on Friday. “The Minister of Health, Dr Frank Anthony is saddened ...

1 year 6 months ago

Health, News, Dr Carissa Etienne, Guyana, Ministry of Health, obituary, PAHO/WHO, Public Health

News Archives - Healthy Caribbean Coalition

8th Caribbean Alcohol Reduction Day (CARD) 2023

8th Caribbean Alcohol Reduction Day (CARD) 2023.

On December 1st, the Healthy Caribbean Coaliiton (HCC) co-hosted The 2023 Conference on the Harmful Use of Alcohol in the English-Speaking Caribbean alongside its partners, The UWI Faculty of Medical Sciences, St. Augustine and the Eastern Caribbean Health Outcomes Research Network (ECHORN). The Conference was held at the UWI St. Augustine Campus, and live-streamed via the Zoom platform in recognition of the 8th Caribbean Alcohol Reduction Day (CARD).

This hybrid conference event was conceptualized by HCC Alcohol Policy Advisor, Professor Rohan Maharaj, and featured presentations from regional academics and public health experts, working in the field of alcohol research and policy. Seventeen (17) presentations were delivered, covering a wide range of topics including the impact of alcohol on public health, regional policy interventions, and the latest research findings. Lay summaries from those presentations can be found here: (click on the images below to enlarge)

The HCC and partners, with the support of PAHO, have hosted annual CARD events over the last seven years, under various themes and titles: The Misuse of Alcohol (2016); Drink Less, Reduce Cancer (2017); Youth: Let’s Talk about Alcohol (2018); Women and Alcohol (2019); Alcohol and COVID-19 (2020); Live Better, Drink Less: Challenges and Opportunities in the Caribbean (2021) and ‘The WHO Global Alcohol Action Plan (GAAP) 2022-2030 – Priorities / Implications for the Caribbean’ (2022).

This year’s hybrid conference theme was entitled “Alcohol Research- Evidence for Action and attracted over 100 virtual and 36 in-person attendees.

The objectives of the Conference and by extension, CARD 2023, were:

  1. To provide an update on regional progress and priorities in alcohol policy development and implementation including discussion of barriers and opportunities.
  2. To showcase alcohol research from across the English-speaking Caribbean.
  3. To discuss how to better utilize research to advocate for accelerated implementation of alcohol policies in the Caribbean.
  4. To highlight alcohol advocacy.

Throughout the day, four (4) sessions were held surrounding the issues of alcohol and population-based studies, regional policy, social impact and medical issues. Each session was followed by a brief Q&A segment.

The HCC and partners have held an annual Caribbean Alcohol Reduction Days (CARD) since 2016 you can find details of the other CARD days here.

The post 8th Caribbean Alcohol Reduction Day (CARD) 2023 appeared first on Healthy Caribbean Coalition.

1 year 6 months ago

Alcohol Advocacy, CARD, News, Slider, Webinars

caribbeannewsglobal

PAHO – UNAIDS highlights AIDS as a public health problem

WASHINGTON, USA, (PAHO) – On World AIDS Day December 1, 2023, the Pan American Health Organization (PAHO) and the Joint United Nations Program on HIV/AIDS (UNAIDS) highlight the key role of communities and civil society in the provision of HIV information and services, such as testing, prevention and treatment, in Latin America and the Caribbean.

“We must recognize the fundamental part that communities play in accelerating the HIV response,” Dr Jarbas Barbosa, PAHO director said. “Today, let us renew our commitment and support for community leadership as we work together to eliminate AIDS in the region of the Americas.”

Let communities lead is the theme for World AIDS Day 2023, emphasizing the role that organizations led by people most disproportionately affected by the human immunodeficiency virus (HIV) play in the response to this four-decade epidemic.

“We are on the home stretch when it comes to ending AIDS as a public health challenge, but we will only achieve this goal if we empower the most affected communities that are being left behind,” Luisa Cabal, regional director of UNAIDS for Latin America and the Caribbean said. “Community leadership is essential in all HIV plans and programs, which must also have financing and protective regulations for their operation.”

To support the expansion of services to key populations and people living with HIV, PAHO and UNAIDS launched the “I am key” initiative in eleven countries in Latin America. This effort has led to strengthened partnerships with communities and civil society to support an accelerated response and people-centred service models.

It is essential that communities are empowered to develop their own strategies and reach those who need it most with information, HIV self-testing, antiretrovirals as a method of prevention (known as PrEP), and treatment to reach an undetectable viral load and break the chain of transmission.

As spaces free of stigma and discrimination, services led by community groups also increase acceptance and retention in care for gay men and other men who have sex with men, sex workers, trans people, and drug users – populations considered key in the response to HIV and among whom the highest number of new infections are reported.

In Latin America and the Caribbean, around 2.5 million people live with HIV. In 2022, about 130,000 people acquired the virus and 33,000 lost their lives from AIDS-related causes.

Expand PrEP to prevent new cases of HIV

Advances in medicine and public health have allowed rapid diagnosis and methods for combined prevention and effective treatment against the virus. A person with HIV who adheres to treatment no longer transmits the virus, and a healthy person who takes PrEP has 99 percent protection against HIV.

The region has also made great efforts to advance the implementation of PrEP, which is reflected in an increase in the number of countries with public health policies on PrEP and its greater availability. However, the number of people receiving it needs to be rapidly increased to prevent new cases of HIV.

Disseminating information to communities can support increased demand for PrEP, especially among those at highest risk of exposure. Additionally, through the PAHO Strategic Fund, countries in the Americas can purchase PrEP at affordable prices, a fundamental support given the limited resources of some health ministries.

1 year 6 months ago

Health & Fitness, Latest Articles, News, Organisation

Health | NOW Grenada

ACB Grenada Bank helps beat heat at General Hospital

“The fans will be strategically placed throughout various areas of the hospital and will significantly improve the overall atmosphere”

View the full post ACB Grenada Bank helps beat heat at General Hospital on NOW Grenada.

“The fans will be strategically placed throughout various areas of the hospital and will significantly improve the overall atmosphere”

View the full post ACB Grenada Bank helps beat heat at General Hospital on NOW Grenada.

1 year 6 months ago

Business, Community, Health, PRESS RELEASE, acb grenada bank, edwin francis, fan, gayton lacrette, general hospital

Belize News and Opinion on www.breakingbelizenews.com

Ministry of Health and Wellness hosts World Aids Day Health Fair in Belmopan

Posted: Friday, December 1, 2023. 10:14 am CST.

By Zoila Palma Gonzalez: World Aids Day is recognized globally on December 1.

The day is set aside to bring together people from around the world to raise awareness about HIV/AIDS and demonstrate international solidarity.

The day is being observed under the theme, “Let communities lead”.

Posted: Friday, December 1, 2023. 10:14 am CST.

By Zoila Palma Gonzalez: World Aids Day is recognized globally on December 1.

The day is set aside to bring together people from around the world to raise awareness about HIV/AIDS and demonstrate international solidarity.

The day is being observed under the theme, “Let communities lead”.

World Aids Day is an opportunity to reflect on the progress made to date, to raise awareness about the challenges that remain to achieve the goals of ending AIDS by 2030 and to mobilize all stakeholders to jointly redouble efforts to ensure the success of the HIV response.

The Ministry of Health and Wellness (MOHW) is hosting a World Aids Day Health fair today in Belmopan.

The fair is being held at the steps of the National Assembly.

The Ministry will be offering free HIV and Syphilis testing, Hepatitis B testing and glucose and blood pressure checks.

The fair commenced at 9am and ends at 3pm.

 

Advertise with the mоѕt vіѕіtеd nеwѕ ѕіtе іn Belize ~ We offer fully customizable and flexible digital marketing packages. Your content is delivered instantly to thousands of users in Belize and abroad! Contact us at mаrkеtіng@brеаkіngbеlіzеnеwѕ.соm or call us at 501-601-0315.

 

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1 year 6 months ago

Health, last news

PAHO/WHO | Pan American Health Organization

Statement on the passing of PAHO Director Emeritus, Dr. Carissa F. Etienne

Statement on the passing of PAHO Director Emeritus, Dr. Carissa F. Etienne

Cristina Mitchell

1 Dec 2023

Statement on the passing of PAHO Director Emeritus, Dr. Carissa F. Etienne

Cristina Mitchell

1 Dec 2023

1 year 6 months ago

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

18 ICU Patient deaths Due to Lack of Oxygen: Hospital held guilty of administrative negligence, slapped Rs 20 lakh compensation

Chennai: More than seven years after 18 ICU patients of MIOT Hospital died due to lack of oxygen, the Tamil Nadu State Consumer Disputes Redressal Commission held the hospital liable for administrative negligence.

The complaint alleged that the hospital failed to anticipate and manage flooding during the rainy season even though the government agencies warned about the same. This resulted in a power outage and life support systems such as ventilators in the Medical ICU located in the basement, failed during the flood. Among the 18 patients who died in the incident, the husband of the complainant was also one.

"...it is obvious that failure of both the power & back-up facilities and the life support system, which were under the management and control of the Hospital at the time of calamity, was due to the negligent ignorance of the hospital’s administration to diligently foresee the disaster despite prior information and thereby, they failed in averting the loss of human lives and protecting the infrastructure. A case of administrative negligence is thus clearly made out and there is no difficulty for this Commission to fix the liability upon the Hospital..." held the HC bench.

Therefore, the State Consumer Court directed the hospital to pay a compensation of Rs 20,00,000 to the complainant. Apart from the amount of the compensation, the hospital has been directed to pay an additional cost of Rs 2 lakhs.

The matter goes back to 2015 when the husband of the complainant suffered a head injury and when he was taken to a hospital, he was diagnosed with Acute Hemorrhagic Stroke as well as Brain Stem Hemorrhage. Later, to avail insurance coverage, the patient was shifted to MIOT hospital, where he was diagnosed with Hypertensive Brainstem Bleed with Status Epilepticus and he was admitted to the Intensive Care Unit (ICU).

He went into unconsciousness due to obstruction in breathing and, after undergoing a procedure called Tracheostomy and intubation, his breathing condition was stabilized with Ventilator Support.

There was a restriction on the side of the hospital regarding the attendant's presence after specific hours and on 1st December and the consecutive two days, the complainant could not gain access to the hospital due to heavy rains and the release of water in the Adyar River generating floods.

As per the complainant, the hospital authorities failed to inform her about the flood situation and it was only through media announcements on December 04, 2015 that she finally got to know about her husband's death.

Referring to the death certificate, the complainant alleged that it was cleverly cooked up indicating that the ailments diagnosed at the time of admission were the cause of death. However, in reality, the complainant's husband along with many other patients in the ICU had all died due to the non-availability of Ventilator Support. She claimed that her husband's death was not a direct result of head injury and complications and rather it was obviously due to non-supply of oxygen.

It was alleged that despite suffering severe inundation earlier in November, the hospital did not advise the patients to move to other Hospitals. It ignored all prior warnings issued by the State Government authorities and it was only on 3rd December evening when the management began to evacuate the patients. Referring to these factors, the complainant emphasised on clear negligence and carelessness on the part of the hospital authorities and argued it to be a fit case for applying the doctrine of res ipsa loquitor. 

Medical Dialogues had earlier reported about the case and at that time, the MIOT Hospitals had denied negligence on its part. While responding to a notice issued by the first bench, headed by Chief Justice Sanjay Kishan Kaul and Justice M M Sundaresh, who was considering a petition by social activist 'Traffic' Ramaswamy, the hospital had said there was no negligence on the part of the hospital and the patients had not died of lack of oxygen, as alleged.

Also Read: Chennai: MIOT Hospitals Denies Negligence Led To Death Of 18 Patients

Before the consumer court as well, the hospital denied negligence. It argued that the patient was an alcoholic and he had various severe health issues, including hypertension, diabetes, and lung complications. Addressing the issue of flood, they argued that they had to face a situation beyond their control as a result of the overflowing Adyar River. The overflowing of water from the said rover inundated the Chocolate Factory and thereafter, it breached the wall of the hospital and engulfed the building which led to a great loss.

They submitted that as a result of the heavy rains, the entire city of Chennai experienced power failure as well as Kancheepuram District and the hospital had no control over the rainfall or the release of water. However, they took necessary steps to rescue and assist the patients by shifting them to other hospitals in the City.

At this outset, the Hospital also referred to the decision of the Madras High Court in this regard. While considering the PIL filed in 2015, the HC bench had rejected all allegations made against the hospital regarding the deaths that occurred during the floods and directed the police authorities to file a final report after the due investigation.

Denying any kind of negligence on their part, the hospital submitted that the complainant's husband succumbed to his illness due to refractory status epilepticus, brain stem hemorrhage, septic shock, acute kidney injury – on acute peritoneal dialysis, type-II Diabetes Mellitus and Hypertension, after receiving a high-end medical care and treatment and the cause of death as given in the death certificate by the hospital was also endorsed in the Post-mortem certificate issued by the Government Hospital.

While considering the matter, the Consumer Court observed that for administrative negligence, the burden of proof lies upon the Hospital to establish that all necessary and reasonable care was taken by them to prevent the harm that was possible from a foreseeable calamity or danger.

Referring to the case at hand, where the complainant alleged that there was failure to take necessary prior preventive measures anticipating rains and floods, the Commission observed that "...merely because the power outage and the consequent life support failure was caused due to heavy flooding, the Hospital authorities cannot on that account alone seek to be absolved without showing something further to indicate that preventive and proactive measures were taken well in advance and that, despite their anticipatory measures, the mishap had become inevitable."

"...despite the ability to foresee and diligently prepare for any emergency situation that was well fathomable from the weather forecasts frequently updated, the administration of the Hospital deliberately failed to take any real anticipatory measure to protect the power units and the critically-ill patients kept at the lower floors from the floods of invasive nature and such obvious failure of the OP clearly depicts their glaring administrative negligence," opined the Commission as it held the Hospital liable.

The consumer court also held the hospital negligent for failure to shit the patients and noted, "With ordinary diligence and exercise of a little more care and caution, beforehand shifting of the patients at the Medical ICU could have been done either to other hospitals or to the elevated floors or to the international block which is said to have had the full-fledged facilities even when the other parts of the Hospital lacked the same; but, that was not done which again shows that there was a negligence which, in our view, although was not willful, had resulted in breach of duty to ensure continuous availability of life support to the patient/s, who was/were in dire need of the ventilator support which was alternated with a manual ventilator support that did not work for him/them for continuation of the medical treatment."

"Therefore, when the facts from different sources are appreciated collectively as highlighted above, it is quite apparent that there was a glaring failure on the part of the Hospital in foreseeing the danger despite clear information and warnings and in self-reading the weather atmosphere and, due to such negligent conduct, they remained indolent and fell short to show the anticipated preparedness expected of them as a distinguished medical care provider," it further observed.

The commission opined that the hospital's failure of life support facilities acted as a contributing factor to the death of most of the patients, who were critically ill.

Referring to the order by the High Court bench, the consumer court clarified that the order of the HC bench did not cover the "negligence" issue but focused only on the issue of unauthorised construction.

Although the Commission held the hospital liable for administrative negligence, it also noted that even though the magnitude of such negligence was undoubtedly high, it was not a willful negligence.

Granting Rs 20 lakh as compensation, the Commission noted, "...it should only be proportionate by considering the other side of the fact that the patient was already battling for his life with serious illness and that the negligence was not a direct cause of his death but it was only contributory in nature and accordingly, we are inclined to award a sum of Rs.20,00,000/- which, in our opinion, would meet the ends of justice."

The order stated, "In the result, by holding that the complainant has made out a case of administrative negligence on the part of the OP that served as a contributing factor for the death of her husband, we allow the Complaint in part, directing the OP to pay to the complainant a sum of Rs.20,00,000/- (Rupees Twenty Lakh only) as compensation besides costs of Rs.2,00,000/- (Rupees Two Lakh only), which shall be paid within a period of 6 (six) weeks from the date of receipt of a copy of this order, failing which, the said sum shall carry interest @ 9% p.a. from the date of the filing of the complaint till the date of realization."

To read the order, click on the link below:

https://medicaldialogues.in/pdf_upload/miot-hospitals-negligence-226718.pdf

Also Read: 14 patients die in Chennai hospital

1 year 6 months ago

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Turkey launches investigation into 19 pharma cos

Ankara: Turkey's competition authority said on Thursday it had launched an investigation into 19 pharmaceutical companies to determine whether they had violated competition law.

In a statement, the authority said it had decided on Nov. 9 to launch the probe into companies including AstraZeneca, Bayer, Glaxosmithkline, Johnson & Johnson, Bausch & Lomb, Sanofi and Pfizer. It provided no further details.

Asked about the matter, AstraZeneca said it does not comment on ongoing investigations as a matter of policy.

Glaxosmithkline, Sanofi and Germany's Merck KGaA all said they were fully cooperating with competition authorities in Turkey, but did not elaborate further.

In a statement, BASF said it was assessing the matter and was committed to high standards of legal compliance and business ethics.

AbbVie, Abdi Ibrahim, Bausch & Lomb, Bayer, Ilko, Johnson & Johnson, Liba, Menarini, Michael Page International, Panasonic, Pfizer, SIFI, and World Medicine could not immediately be reached for comment.

Read also: Misrepresentation of COVID vaccine efficacy: Texas Attorney General sues Pfizer

1 year 6 months ago

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India topped Southeast Asia Region in malaria cases, deaths in in 2022, shows WHO report

Geneva: India topped countries in the South-East Asia Region for the most number of malaria cases and deaths in 2022, according to the 2023 World malaria report published by the World Health Organization (WHO) on Thursday.

The report showed that in 2022, nine countries in the South-East Asia Region contributed to about 2 per cent of the burden of malaria globally (5.2 million cases).

Geneva: India topped countries in the South-East Asia Region for the most number of malaria cases and deaths in 2022, according to the 2023 World malaria report published by the World Health Organization (WHO) on Thursday.

The report showed that in 2022, nine countries in the South-East Asia Region contributed to about 2 per cent of the burden of malaria globally (5.2 million cases).

Most malaria cases in the Region were concentrated in India (66 per cent) and about 94 per cent of deaths were in India and Indonesia.

Also Read:Haryana reports fall in malaria cases by 93 percent, no case of chikungunya till now

Globally, there were estimated 249 million malaria cases in 2022, exceeding the pre-pandemic level of 233 million in 2019 by 16 million cases.

There were also an additional five million malaria cases in 2022 over the previous year and five countries bore the brunt of these increases, the report said. Pakistan saw the largest increase, with about 2.6 million cases in 2022 compared to 500,000 in 2021. Significant increases were also observed in Ethiopia, Nigeria, Papua New Guinea and Uganda.

Meanwhile, in the 11 countries that carry the highest burden of malaria, rates of new infections and deaths have levelled off following an initial upsurge during the first year of the pandemic.

These countries, supported through the WHO “High burden to high impact” approach, saw an estimated 167 million malaria cases and 426,000 deaths in 2022.

The report emphasised on the growing threat of climate change in increasing malaria cases. It showed that changes in temperature, humidity and rainfall can influence the behaviour and survival of the malaria-carrying Anopheles mosquito. Extreme weather events, such as heatwaves and flooding, can also directly impact transmission and disease burden.

Catastrophic flooding in Pakistan in 2022, for example, led to a five-fold increase in malaria cases in the country.

“The changing climate poses a substantial risk to progress against malaria, particularly in vulnerable regions. Sustainable and resilient malaria responses are needed now more than ever, coupled with urgent actions to slow the pace of global warming and reduce its effects,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General, in a statement.

Climate variability is expected to have indirect effects on malaria trends through, for example, reduced access to essential malaria services and disruptions to the supply chain of insecticide-treated nets, medicines and vaccines. Population displacement due to climate-induced factors may also lead to increased malaria as individuals without immunity migrate to endemic areas.

There has also been progress toward malaria elimination in many countries with a low burden of the disease. In 2022, 34 countries reported fewer than 1000 cases of malaria compared to just 13 countries in 2000. This year alone, three more countries were certified by WHO as malaria-free -- Azerbaijan, Belize and Tajikistan -- and several others are on track to eliminate the disease in the coming year.

The report also cites achievements such as the phased roll-out of the first WHO-recommended malaria vaccine, RTS,S/AS01, in three African countries. In October 2023, WHO recommended a second safe and effective malaria vaccine, R21/Matrix-M. The availability of two malaria vaccines is expected to increase supply and make broad-scale deployment across Africa possible.

Also Read:WHO Recommends new Malaria Vaccine for children which is cost-effective and efficient

1 year 6 months ago

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