Health – Dominican Today

Return! Cases of chikungunya are being reported: practical tips for prevention

The Ministry of Public Health reported last Thursday that three people from Cuba have tested positive for chikungunya, a disease transmitted by the Aedes aegypti mosquito, the same vector that transmits dengue and Zika.

Due to rainy seasons and the proliferation of breeding sites, this disease continues to pose a risk to the Dominican population; therefore, preventive measures must be taken to curb the development and growth of this mosquito.

Preventive measures

The World Health Organization (WHO) has specified that eliminating and controlling Ae. Aedes aegypti mosquito breeding sites reduce the chances of chikungunya and dengue virus transmission.

They also reported that, like dengue, this virus requires a comprehensive response involving several areas of action, from health to education and the environment.

These measures include eliminating or destroying mosquito breeding sites:

1. Avoid storing water in outdoor containers (flower pots, bottles, containers that can accumulate water) to prevent them from becoming mosquito breeding sites.

2. Cover domestic water tanks or reservoirs to prevent mosquitoes from entering.

3. Avoid accumulating trash, and dispose of it in closed plastic bags and keep it in closed bins.

4. Uncover drains that can leave water stagnant.

5. Using screens on windows and doors also helps reduce mosquito contact with people.

5 hours 48 min ago

Health, Local

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Mild Pancreatic Duct Dilatation Linked to Pancreatic Cancer Risk: Study

USA: A prospective cohort study published in Gastro Hep Advances has revealed that even mild dilatation of the main pancreatic duct (MPD) significantly raises the risk of pancreatic cancer in individuals already at high risk.       

USA: A prospective cohort study published in Gastro Hep Advances has revealed that even mild dilatation of the main pancreatic duct (MPD) significantly raises the risk of pancreatic cancer in individuals already at high risk.       

Participants with baseline duct dilatation showed a 16% cumulative risk of developing high-grade dysplasia or pancreatic cancer within five years, rising to 26% at 10 years. Those with any degree of duct dilation were 2.6 times more likely to experience disease progression, with the risk particularly pronounced in patients harboring three or more pancreatic cysts during ongoing surveillance.The study led by Elizabeth Abou Diwan and colleagues at the Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, sheds light on the clinical implications of mild MPD dilation in asymptomatic high-risk individuals (HRIs). While MPD dilation has been recognized as a potential early marker of an obstructing pancreatic mass, its significance in individuals undergoing routine pancreatic surveillance has remained unclear.The researchers aimed to determine the prevalence of ductal dilation in this population and assess its relationship with neoplastic progression, including high-grade dysplasia and pancreatic ductal adenocarcinoma (PDAC).The study analyzed data from 641 HRIs enrolled in the Cancer of the Pancreas Screening cohort studies, followed for a median of 3.6 years. MPD dilation was defined as a diameter of ≥4 mm in the pancreatic head, ≥3 mm in the body, and ≥2 mm in the tail. The team used Cox regression and time-varying covariate analysis to evaluate the risk of neoplastic progression and applied Kaplan–Meier methods to estimate time-to-progression from both baseline endoscopic ultrasound and baseline duct dilation. The study revealed the following findings:

  • 97 participants (15%) showed main pancreatic duct (MPD) dilation without any detectable obstructing mass.
  • Among these, 10 individuals (10.3%) developed neoplastic progression within a median of two years after initial detection.
  • HRIs with baseline MPD dilation had a cumulative probability of high-grade dysplasia or pancreatic ductal adenocarcinoma of 16% at five years and 26% at ten years.
  • The presence of any ductal dilation increased the risk of progression 2.6 times.
  • Risk was particularly high in patients with three or more pancreatic cysts, with an adjusted hazard ratio of 9.07.

The study concludes that even minimal MPD dilation, in the absence of an apparent obstructing lesion, serves as an independent risk factor for neoplastic progression in high-risk individuals. Researchers suggest that HRIs with isolated ductal dilation should undergo shorter surveillance intervals, particularly when multiple pancreatic cysts are present.The authors acknowledge certain limitations, including the single-center design and the relatively small number of patients who developed neoplastic progression—a common challenge in studies of high-risk pancreatic populations. However, the findings highlight the importance of careful monitoring of MPD changes, even when no mass lesion is evident, for early detection and intervention in pancreatic cancer.Reference:Diwan EA, Saba H, Blackford AL, Dbouk M, Chu L, He J, Burkhart R, Hruban RH, Goggins M, Canto MI. Mild Dilatation of the Main Pancreatic Duct Is a Risk Factor for Progression to Pancreatic Cancer in High-Risk Individuals. Gastro Hep Adv. 2025 Sep 12;4(10):100802. doi: 10.1016/j.gastha.2025.100802. PMID: 41142531; PMCID: PMC12547912.

5 hours 54 min ago

Gastroenterology,Oncology,Radiology,Surgery,Gastroenterology News,Oncology News,Radiology News,Surgery News,Top Medical News,Laboratory Medicine,Laboratory Medicine News,Latest Medical News

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No medical negligence, but Tinea corporis treatment deficit- Bengal doctor slapped Rs 2.5 lakh compensation

New Delhi: The National Consumer Disputes Redressal Commission (NCDRC) recently directed a doctor from West Bengal to pay Rs 2.5 lakh to a patient, whose skin condition did not improve despite undergoing treatment.

New Delhi: The National Consumer Disputes Redressal Commission (NCDRC) recently directed a doctor from West Bengal to pay Rs 2.5 lakh to a patient, whose skin condition did not improve despite undergoing treatment.

Even though the Apex Consumer Court found the allegations of medical negligence in the diagnosis of the disease and administration of steroids as false, it noted that the patient's condition did not improve, and she had to suffer a lot for not having received the benefits of the treatment administered by the treating doctor.

Accordingly, setting aside the State Commission's earlier order of directing the doctor to pay Rs 10 lakh, the Apex Consumer Court reduced the amount and directed the same to be paid to the patient for the deficit in the administration of corrective medicines.

The complainant had alleged deficiency in service and medical negligence against the treating doctor for having failed to take due care in diagnosing the skin disease and having administered medicines based on an experimental treatment that severely and adversely affected the metabolism of the patient as a whole, from which she suffered tremendously and also suffered substantial physical damage.

It was alleged that the treating doctor had administered steroids that resulted in complications, and apart from that, immunosuppressant drugs were also prescribed in disproportionate overdoses, which further aggravated the same and caused incalculable harm to the physique of the complainant.

The treating doctor refused to receive the notice, which was returned with the postal remark of refusal. Consequently, the complaint proceeded ex-parte to the appellant and was ultimately allowed by the State Commission by imposing damages to the tune of Rs 5 lakhs on the appellant and Rs 10,000 as litigation cost.

When the complainant filed an Execution, the treating doctor filed an appeal before the NCDRC, arguing that he had no knowledge of the proceedings prior to the steps taken in the Execution proceedings.

NCDRC in its order dated 09.06.2022, stayed the State Commission's order with a direction to the doctor to pay Rs 20,000 to the complainant and depositing 50% of the decretal amount before the State Commission

The counsel for the treating doctor argued that the drugs which were prescribed were in accordance with the medical protocol and after taking due care. It was also urged that there was no expert evidence led by the complainant to demonstrate that there was any deficiency or negligence either in diagnosing or treating the disease as prescribed by the treating doctor. The counsel argued that in the absence of any such expert evidence, the inferences drawn by the State Commission are based on some sort of personal knowledge without there being any scientific basis for the same.

After perusing the facts as brought on record, the NCDRC bench observed that when the complainant went and got herself examined by the treating doctor, the handwritten prescription records a doubt with a question mark of the disease Tinea Corporis also commonly known as “ring worm” which is a superficial fungal infection usually occurring on the arms and legs. It is also described as dermatophytosis. The counsel for the appellant submitted that this was diagnosed and suspected on the very first day by the appellant.

The doctor also prescribed tests including IgE. The prescription also advised Eukart as one of the medicines. The patient was advised to take the medicine and then to come back again. The report revealed that the IgE level was very high, and in this background, the treatment was advised.

At this outset, the Apex Consumer Court observed that this test was dated 10.01.2019, and the second visit made by the patient after the other blood tests etc. were carried out was on 26.01.2019. After having noticed the high level of IgE, the appellant for the first time prescribed injection Tenacort40. This is the only steroid injection which was prescribed by the treating doctor, and that too on 26.01.2019. The medicine Eukart was repeated with advice to visit the doctor again.

Thereafter, the patient arrived on 02.03.2019 and complained of eruptions all over the skin. Blood samples were advised of IgE level once again and other blood tests, including lipid profile, urea creatinine. Tenacort40 was again advised to be administered biweekly in the said prescription. The other laboratory reports of the blood tests including the IgE levels were once again reported and the report dated 29.03.2019 indicated IgE level as 1105, which was higher than the previous report.

The counsel for the appellant that despite steroid having been administered, the level continued to rise and did not indicate any reduction. The third time, the complainant visited the doctor on 30.03.2019 when she was referred to the Dermatologist. The counsel argued that the said prescription nowhere indicated any advice for administration of steroids, but Folitrex 2.5 mg tablet, and immunosuppressant, was prescribed one tablet three times in a week.

It was submitted by the counsel that Folitrex is the generic medicine named Methotrexate, which is an immunosuppressant and also a chemo drug. The counsel submitted that the said medicine is administered for a large number of diseases, including Arthritis, cancer and other such diseases where immunosuppressants are required, including dermatitis that was also diagnosed in the prescription dated 30.03.2019.

The top consumer court noted that the counsel for the complainant was that this continued administration of steroid and the immunosuppressant drugs led to the complication that was aggravated due to the administration of another medicine, Furosemide. It also took note of the fact that immediately after the prescription dated 30.03.2019, the complainant shifted for treatment to the Narayana Hospital, where she was admitted on 03.04.2019 and was discharged on the same date.

"We have considered the submissions raised and have perused the complaint, the allegations made and the evidence adduced. The findings recorded by the State Commission are undoubtedly based on the complaint allegations as the appellant did not contest the matter before the State Commission where it went ex-parte," NCDRC noted.

However, the Apex Consumer Court perused the allegations about the administration of Furosemide medicine. It observed,

"On record are the prescriptions as well as the discharge summary and certificates of the Narayana Hospital where the respondent no. 1 had been later on treated. Neither the prescriptions of the appellant indicate any advice to administer Furosemide nor is there any recital of the said medicine or its equivalent in any of the prescriptions issued by the appellant. The recital contained in the discharge summary of the Narayana Hospital that the patient was on oral Furosemide for three months is nowhere substantiated by the prescriptions that were produced by the complainant herself. The recital therefore in the discharge summary also appears to be without any basis. Thus, paragraph 9 of the complaint referring to the said medicine being administered for months together is without any basis and it is because of this that the State Commission has not accepted the said allegation or even commented upon it. The said allegation therefore in the complaint seems to be false."

"We have then examined the allegation about the administration of Tab. Folitrex (Methotrexate) medicine which we find was prescribed for the first time in the appellant’s prescription dated 30.03.2019. This medicine had not been prescribed earlier. Thus, there was no occasion for the administration of Methotrexate medicine being taken by the complainant for three months," it also noted.

NCDRC observed that shortly after this, the patient was shifted to Narayana Hospital. Therefore, it held that

"There is nothing to substantiate that Methotrexate was taken by the complainant for three months. Even otherwise if it was prescribed for the first time only on 30.03.2019, there was nothing to infer that she had been taking this medicine for the past three months. The Narayana Hospital discharge summary therefore once again recorded a wrong fact of taking Methotrexate for three months. As a matter of fact, the complainant does not seem to have taken the medicine at all, in as much as, immediately upon its prescriptions on 30.03.2019, she chose to switch over to Narayana Hospital on 03.04.2019 which is just three days after the prescription dated 30.03.2019. There was nothing to demonstrate that the medicine had been taken for three months or for that matter even for three days. Accordingly, we find that the discharge summary and certificate of the Narayana Hospital mentions a replication of the allegations in the complaint without even looking into the prescriptions of the appellant."

The Apex Consumer Court also noted that the Narayana Hospital discharge summary records its diagnosis as “Tinea Corporis”. Referring to this, the Commission noted,

"This diagnosis clearly matches with the same suspect diagnosis recorded by the appellant on the first occasion in his prescription dated 05.01.2019. It is therefore clear that there is no error in the diagnosis made by the appellant regarding the nature of the disease."

Addressing the allegations regarding the administration of steriods, the Commission noted that the Narayana Hospital indicated that the rashes followed a systematic steroids intake. This diagnosis was made on the same date when the patient was admitted and discharged.

"As noted above, the administration of Furosemide and Methotrexate for three months has been found to be false and based on no evidence. The discharge summary of the Narayana Hospital records these recitals which remain unsubstantiated. There is therefore every reason to assume that the discharge summary was prepared by the Narayana Hospital without looking into the documents," it held.

"Coming to the administration of steroids, we find that the Tenacort40 injection was first prescribed on 26.01.2019. It was almost after more than a month that it was again prescribed on 02.03.2019. In spite of the said administration, the IgE level of the complainant did not reduce and from 1104 on 10.01.2019, it rose to 1105 on 29.03.2019. It is therefore obvious that the administration of Tenacort40 which was a steroid did not have any impact indicating any control over the infection. No further prescription demonstrates any infusion or injection of a steroid to the complainant. In such circumstances, the conclusion drawn in the diagnoses of Narayana Hospital that the rashes followed the steroid intake in a systematic way is not exactly established. To the contrary, Tinea Corporis already existed when the complainant was examined by the appellant on 05.01.2019," it oberved.

Noting that the complainant contended attributed negligence to the treating doctor for administering sterioids, which affected her health and the rash spread over the whole body, the Commission clarified that neither Furosemide nor Folitrex was taken for three months as alleged. Folitrex was an immunosuppressant and according to the learned counsel and the literature relied on by him, it is a drug which is administered for multifarious symptoms and not only for one disease.

However, the Commission noted that the doctor failed to explain how the rashes spread all over duing the treatment from 05.01.2019 till 30.03.2019. "This was almost a period of close to three months and the complainant does not seem to have been cured with the medicines that were prescribed by the appellant. We do not find any explanation coming forth on this count even if evidence was lacking with regard to the administration of Furosemide and Methotrexate for three months," it observed.

Despite this observation, the NCDRC bench held that the arguments made by the complainant did not make out any case of medical negligence regarding the allegation of the administration of unnecessary medicines.

"The treatment advised by the complainant cannot be said to be experimental nor any expert opinion has been led before the State Commission to establish the same. In such matters, it will not be appropriate to apply the principles of res ipsa loquitur. It is true that expert opinions are not binding, but as noted above, we have derived our conclusions based on the prescription and the records filed by the complainant herself," observed the NCDRC bench.

However, taking note of the fact that the treatment did not improve the complainant's condition and how the patient suffered, the Commission decided to release the amount deposited under the interim order dated 09.06.2022 to the complainant.

"...we find that the impugned order cannot be sustained for all the reasons stated hereinabove, but at the same time, we also do not find any valid explanation by the appellant as to why the rashes spread over the whole body in spite of the treatment meted by the appellant for almost three months. There seems to be some deficit in the administration of corrective medicines. In this background, the amount deposited under the interim order dated 09.06.2022 deserves to be released to the complainant for meeting all the expenses borne for the treatment as also the sufferance of the respondent - complainant having not received the benefits of the treatment administered by the appellant. To the contrary, the rashes had spread all over the body, in these circumstances, the amount deposited before the State Commission under the interim order dated 09.06.2022 shall be released to the respondent no. 1. However, the rest of the amount as awarded by the State Commission is set aside and the appeal is partly allowed in view of the findings and the conclusions drawn hereinabove," it ordered.

To view the order, click on the link below:

https://medicaldialogues.in/pdf_upload/ncdrc-no-med-negligence-311665.pdf

Also Read: No negligence in sinus surgery case with post-operative eye complications, Consumer court grants relief to doctor

15 hours 39 min ago

Editors pick,State News,News,Health news,Delhi,Doctor News,Medico Legal News,Latest Health News

Health – Dominican Today

Protest Nurses raise their voices for their demands: “We are not asking for anything unreasonable.”

With banners in hand, members of the National Union of Dominican Nursing Services (UNASED) protested this Friday in front of the Maternidad Nuestra Señora de la Altagracia hospital to demand that the central Government address a series of grievances that, according to them, have been pending for years.

“We are not asking the president for anything out of this world. What we are asking for are the demands that they have had and known about for five years,” said one of the protesters.

The group pointed out that Dr. Mario Lama, executive director of the National Health Service (SNS), promised to reclassify 1,000 positions from assistant to bachelor’s degree this year; however, he has only implemented about 200 of them.

“Of those demands, they have only given a paltry 25 percent in three installments. Now, as for the reclassification of positions, nurses who went to college starving, perhaps even walking to school to prepare themselves, today continue to be paid as assistants in hospitals,” said another of the protesters.

Similarly, union representatives warned that their struggle will continue to escalate until the authorities decide, while emphasizing that their current salaries are not enough to cover the basic family basket, “which is around 47,000 and something.”

“We are not talking about a raise, but rather recognition of the incentive for time in service and those other demands that date back to 1990-95. Mr. President, respond to the nurses; this will go as far as the authorities want it to go,” they said.

What they are asking for

Among the demands made by the nurses are: a 100% salary increase for staff; the reclassification of nursing assistants to licensed nurses; the streamlining of nursing pensions; improvements in working conditions in hospitals and greater safety for staff; the construction of a clubhouse for nurses; as well as incentives, among others.

1 day 8 hours ago

Health, Local

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Renowned Jamshedpur Surgeon Dr Nagendra Singh passes away

Jamshedpur: Dr. Nagendra Singh, one of Jamshedpur’s most compassionate and influential medical pioneers, passed away on Wednesday, leaving the city and the entire state of Jharkhand in profound grief.

Jamshedpur: Dr. Nagendra Singh, one of Jamshedpur’s most compassionate and influential medical pioneers, passed away on Wednesday, leaving the city and the entire state of Jharkhand in profound grief.

A renowned laparoscopic surgeon and the visionary founder of Mango-based Ganga Memorial Hospital, Dr. Singh devoted his life to healing the poor and underserved, earning him the enduring title of “Messiah of the Poor.” 

Dr. Singh’s health took a critical turn two days ago, leading to an emergency airlift to Apollo Hospital, New Delhi, for advanced treatment. Despite intensive care, he breathed his last with his wife by his side. His mortal remains are expected to return to Jamshedpur by late evening.

Over a distinguished career spanning more than 30 years, Dr Singh performed nearly one lakh surgeries. Remarkably, over 14,000 of these procedures were done entirely free of cost. His medical journey began with an MBBS from Magadh University and an MS (Surgery) from RIMS, Ranchi, after which he dedicated himself to serving remote and underserved communities through surgical camps.

Also Read:Udupi's 5-rupee doctor, Dr K P Shetty, passes away at 77

In memory of his mother, the late Ganga Devi, Dr Singh established Ganga Memorial Hospital in Mango, transforming it into a sanctuary for patients who lacked financial resources. His generosity knew no bounds. His humility defined him. When people could not afford treatment, he would accept vegetables as a gesture of gratitude — a practice that earned him the endearing nickname “Sabzi Wale Doctor.”

He adopted five villages of the tribal Sabar community of Jharkhand and was responsible for providing free treatment and medicines to all the patients there, and if needed, taking them to their homes by vehicle, reports Jagran.

Dr. Singh’s humanitarian contributions earned him accolades from various quarters, including recognition from former Jharkhand Governor and current President of India, Droupadi Murmu. The Jharkhand government had twice recommended him to the Central Government for the Padmashree award.

For those whose lives he touched, Dr. Singh was not just a doctor — he was hope itself. His humility, accessibility, and unwavering dedication elevated him to the stature of a guardian angel in white, reports the Avenue Mail.

Also Read:Renowned Assam Surgeon Dr Sumakanta Shyam passes away at 78

Today, not only Jamshedpur but the entire state of Jharkhand grieves the loss of a humanitarian doctor. His passing marks the end of an era, but his example will forever inspire future generations of medical professionals.Dr. Singh is survived by his wife, a daughter who is a doctor, and a son who is pursuing MBBS. His daughter recently married the son of the former principal of Mahatma Gandhi Memorial (MGM) Medical College.

1 day 13 hours ago

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Health | NOW Grenada

REOI: OECS Regional Health Project

Expressions of interest in the Consultancy to Develop and Operationalise an Emergency Medical Service System must be submitted via the E-Procurement portal on or before 19 December 2025

View the full post REOI: OECS Regional Health Project on NOW Grenada.

Expressions of interest in the Consultancy to Develop and Operationalise an Emergency Medical Service System must be submitted via the E-Procurement portal on or before 19 December 2025

View the full post REOI: OECS Regional Health Project on NOW Grenada.

2 days 5 hours ago

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Health – Dominican Today

Health Ministry identifies three Chikungunya cases from Cuba

Santo Domingo.- The Dominican Republic’s Ministry of Health confirmed three imported cases of chikungunya detected in travelers from Cuba but emphasized that there is currently no community transmission in the country.

Santo Domingo.- The Dominican Republic’s Ministry of Health confirmed three imported cases of chikungunya detected in travelers from Cuba but emphasized that there is currently no community transmission in the country. The cases were identified through the national epidemiological surveillance system and confirmed by tests at the Dr. Defilló National Reference Laboratory.

Health Minister Víctor Atallah reassured the population that authorities are monitoring the situation daily and urged the public to reinforce preventive measures. Chikungunya, transmitted by Aedes aegypti and Aedes albopictus mosquitoes, causes fever and intense joint pain similar to dengue.

In response to rising cases in the Caribbean—particularly in Cuba—the ministry has strengthened surveillance nationwide, increased active searches for febrile cases, and intensified vector control measures such as fumigation, elimination of breeding sites, and community education. Health checks also remain heightened at airports, ports, and border points.

Preparedness protocols have been reinforced in health centers to ensure proper diagnosis, clinical management, and timely care, following PAHO/WHO recommendations. Authorities again urged the public to eliminate standing water, cover tanks, use repellents, and support community clean-up and fumigation efforts.

2 days 6 hours ago

Health, Aedes aegypti and Aedes albopictus, Caribbean, chikungunya, cuba, Health checks, mosquitoes, protocols

PAHO/WHO | Pan American Health Organization

Early HIV diagnosis could reduce AIDS-related deaths in Latin America and the Caribbean: PAHO

Early HIV diagnosis could reduce AIDS-related deaths in Latin America and the Caribbean: PAHO

Cristina Mitchell

28 Nov 2025

Early HIV diagnosis could reduce AIDS-related deaths in Latin America and the Caribbean: PAHO

Cristina Mitchell

28 Nov 2025

2 days 8 hours ago

Health | NOW Grenada

SGU awards 30 scholarships to Grenadian students

“Educating Grenadians is central to SGU’s vision and mission. Every scholarship we award and every student we train represents a stronger, healthier future for our nation”

3 days 6 hours ago

Education, Health, PRESS RELEASE, marios loukas, school of medicine, sgu, st george’s university

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Clinical Value of Coronary microvascular dysfunction (CMD) and Vasospastic Angina (VSA) Testing: JACC Advances November 2025

Coronary microvascular dysfunction (CMD) and vasospastic angina
(VSA) are common and clinically important contributors to chest pain in
patients with non-obstructive coronary arteries, and invasive physiologic
testing offers meaningful guidance during routine care. The FlowLab study,
published in JACC Advances, showed that CMD/VSA testing is practical to

Coronary microvascular dysfunction (CMD) and vasospastic angina
(VSA) are common and clinically important contributors to chest pain in
patients with non-obstructive coronary arteries, and invasive physiologic
testing offers meaningful guidance during routine care. The FlowLab study,
published in JACC Advances, showed that CMD/VSA testing is practical to
perform, integrates smoothly into standard catheterization workflows, and
frequently influences management at the time of the procedure. For clinicians,
this reinforces the value of looking beyond angiography when evaluating
persistent angina.

Angina with non-obstructive coronary arteries (ANOCA) –
Cardiologists’ Challenge

Angina with non-obstructive coronary arteries (ANOCA) is a
familiar challenge in cardiovascular practice. These patients often continue to
experience symptoms despite “normal” angiograms, leading to uncertainty
regarding the true cause of their discomfort. CMD and VSA are recognized
mechanisms behind these presentations, but they are often missed because they
cannot be seen on standard imaging. The study provided a timely look at how
U.S. centers are incorporating coronary functional testing into everyday
practice and how such testing improves diagnostic clarity for complex angina.

Study Overview

In this multicenter, real-world assessment, clinicians performed
CMD and VSA testing whenever they felt it clinically appropriate, making the
results directly relevant to daily patient care rather than controlled research
environments. Fourteen U.S. centers participated, using bolus thermodilution to
measure coronary flow reserve (CFR) and index of microcirculatory resistance
(IMR), with optional acetylcholine provocation for vasospasm. Operators had
full discretion over when to perform these evaluations—before or after
angiography, or alongside other physiologic assessments. This flexible approach
ensured that the data reflected true practice patterns rather than
trial-specific protocols. A total of 253 procedures were included in the
analysis.

Key Findings

The results revealed how frequently clinically meaningful
abnormalities are present in patients with nonobstructive coronary disease.

  • Impaired CFR was seen in 43% of the cohort, while 28% had elevated
    IMR—both markers of CMD. Vasospasm testing, performed in roughly half the
    patients, identified positive responses in 57%, highlighting how commonly
    vasospastic mechanisms contribute to symptoms.
  • CMD and VSA occurred individually or in combination, explaining
    why standard angiography alone often fails to provide a full diagnostic
    picture.
  • Importantly, functional testing had direct therapeutic
    consequences. Patients with elevated IMR were much more likely to receive
    additional antianginal therapy (61% vs 29%), and preventive measures were
    frequently intensified based on physiologic abnormalities rather than
    angiographic appearance.

Testing itself was efficient, typically completed in about ten
minutes and easily incorporated into various procedural workflows.

Potential Clinical Implications for Interventionalists

Clinically,
the implications are significant. Relying solely on angiography leaves many
patients without a clear diagnosis, potentially prolonging symptoms and
contributing to repeated evaluations. By integrating CMD and VSA testing into
routine invasive pathways, clinicians can identify the true drivers of ischemic
symptoms and tailor treatment accordingly. Although the study reflects
real-world variability and observational limitations, the consistent presence
of physiologic abnormalities and the immediate shift in management they
prompt—supports the growing role of coronary functional testing in modern chest
pain evaluation. The FlowLab experience underscores that in many patients, the
answers lie beyond the angiogram, and targeted physiologic assessment helps
bridge that diagnostic gap.

Reference: Bergmark BA, Shah S, Toleva O, Maksoud A, Kearney KE, Kobayashi Y, Fahed
AC, Hashim H, Sharma A, Blair J, Chehab BM, Kanakadandi U, Jaffer FA, Jeremias
A, Gross DA, Baljepally R, Ali ZA, Reddy G, Shlofmitz E, Moussa I, Zhang S,
Murphy SA, Ahmed S, Spinelli J, Meinen J, Rapoza RJ, Sabatine MS. Multicenter
Prospective Assessment of Coronary Microvascular Dysfunction: Primary Results
of the FlowLab Study. JACC Adv. 2025 Sep 26;4(11 Pt 1):102179. doi:
10.1016/j.jacadv.2025.102179. Epub ahead of print. PMID: 41014809; PMCID:
PMC12510197.

3 days 15 hours ago

Cardiology-CTVS,Cardiology & CTVS News,Top Medical News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Wearable sleeves show promise for clinical knee & elbow ROM measurement and remote monitoring: study

Goniometers are a common clinical tool for measuring joint range of motion. Wearable sleeves offer a novel and alternative method to measure joint angles, record range of motion (ROM), and remotely track changes in ROM over time. Additionally, they may aid in the surgical planning required for deformity correction.

This investigation compared the reliability and validity of a conventional goniometer to a novel transducer embedded sleeve when measuring flexion and extension of the elbow and knee.

Neufeld E V et al conducted a cross-sectional study of 55 patients (110 elbows, 110 knees) who donned an elbow and knee sleeve embedded with a gallium-based strain sensor. Flexion and extension of the elbow and knee were measured both manually using a goniometer and a wearable sleeve. Agreement between the two devices was assessed via Bland-Altman plots.

The key findings of the study were:

• Regarding elbow flexion, the bias observed between the two devices was 4.6° with LoA spanning from -14.9° to 24.1°. Regarding elbow extension, the bias observed between the two devices was -9.8° with LoA spanning from -25.6° to 6.0°.

• Regarding knee flexion, the bias observed between the two devices was -4.6° with LoA spanning from -35.6° to 26.4°. Regarding knee extension, the bias observed between the two devices was - 2.8° with LoA spanning from -8.9° to 3.3°.

The authors concluded – “The proprietary sleeve investigated in this study demonstrated significant systematic bias relative to the traditional goniometer; therefore, the sleeve needs refinement, and thus, we cannot recommend that it be utilized in the clinical setting at this time. While the device shows some promise, primarily for measuring knee extension, it currently requires substantial refinement before it can obviate the need for the traditional goniometer. Part of this bias may be due to the challenges faced in consistent sleeve placement around the joint. Most importantly, improvements in product development should focus on optimizing the sleeve fit and the reproducible positioning of the strain sensor to address the user-interface challenges present in the current study. Consistent and precise sleeve placement should enhance clinical utility. Further research must demonstrate validity in not only healthy patients but also those with joint pathologies, such as osteoarthritis and ligamentous insufficiency, and include a larger sample size. This study serves as a valuable foundation for this technology, pointing to the possibility that with reduced bias, wireless sleeves may present a new, less cumbersome alternative for measuring joint ROM.”

Further reading:

Agreement Between a Wireless Sleeve and a Goniometer in Measuring Elbow and Knee Range of Motion, Eric V. Neufeld et al Cureus 17(9): e91748. DOI 10.7759/cureus.91748

4 days 6 hours ago

Orthopaedics,Orthopaedics News,Top Medical News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Kochi Hospital emergency dept becomes wedding venue after bride suffers spinal injury

Thiruvananthapuram: In an
extraordinary turn of events, a couple transformed the emergency department of VPS Lakeshore Hospital in Kochi into a wedding venue after the bride suffered a spinal injury in a road accident just hours before the ceremony.  

Thiruvananthapuram: In an
extraordinary turn of events, a couple transformed the emergency department of VPS Lakeshore Hospital in Kochi into a wedding venue after the bride suffered a spinal injury in a road accident just hours before the ceremony.  

The emotional event
unfolded when the woman, who was travelling with her family for bridal makeup in
Kumarakom around 3 a.m., was injured after their vehicle veered off the road
and struck a tree. While locals initially rushed the victims to Kottayam Medical College, she was later shifted to VPS Lakeshore Hospital in Kochi for
advanced care owing to the seriousness of her condition.

Also Read:Karnataka issues guidelines for Sabarimala Pilgrims amid brain-eating amoeba cases

According to India Today, the marriage was supposed
to take place on Friday afternoon in Alappuzha. When the groom reached the
hospital and the doctors briefed him about the serious condition of the bride. After the discussion, both families decided to proceed with the rituals at the scheduled
auspicious moment. With the approval of hospital authorities and the
neurosurgery team, arrangements were swiftly made inside the emergency ward.

Between 12.15 p.m. and
12.30 p.m., surrounded by relatives, doctors, and nurses, the couple exchanged wedding vows while the bride remained on a stretcher. The ceremony, though
brief, took place without affecting ongoing medical services, turning the
hospital’s ER into a poignant scene of love and resilience.

Dr Sudish Karunakaran,
head of the neurosurgery department, stated that the woman was seriously
injured with a spinal injury. She will undergo surgery soon. She works as an
assistant professor at an engineering college in Alappuzha. Despite the sudden
shift in venue, the guests who had assembled at the wedding location were
treated to the originally planned meal, with the festivities continuing in an
unexpected setting – a hospital corridor.

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