Health Archives - Barbados Today

Trinidad and Tobago records 13 dengue-related deaths

Trinidad and Tobago has recorded its 13th dengue-related death with health authorities saying Friday, that the number of cases had surpassed 1,300.

In a statement, the Ministry of Health said there were 1,315 confirmed cases of dengue fever across the country, with 13 fatalities so far this year.

Trinidad and Tobago has recorded its 13th dengue-related death with health authorities saying Friday, that the number of cases had surpassed 1,300.

In a statement, the Ministry of Health said there were 1,315 confirmed cases of dengue fever across the country, with 13 fatalities so far this year.

It said that as of September 5, health authorities have also issued 914 yellow fever notices to property owners and occupiers, urging them to clean up their surroundings to reduce mosquito breeding sites.

Legal action is being considered against 43 property owners for failing to comply with these directives as the ministry reminds the public that dengue is spread by the bite of an infected Aedes Aegypti mosquito.

It is the same type of mosquito that spreads the Zika and chikungunya viruses.

Trinidad and Tobago recorded its first dengue-related death on June 19, when a 65-year-old succumbed to the virus.

The health ministry said that symptoms appear within five to six days of being bitten (and) last for one to two weeks.

It said the symptoms include fever, headache, pain behind the eyes, muscle and joint pains, skin rash, vomiting and diarrhea and that individuals showing such symptoms should seek immediate medical treatment.

SOURCE: CMC

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7 months 2 weeks ago

Health, Regional, Trinidad & Tobago

News Archives - Healthy Caribbean Coalition

2023 CBU Caribbean Media Awards

On August 13, 2024 the 55th Caribbean Broadcasting Union’s Caribbean Media Awards took place in Umaya Hotel, Placencia Belize.

The primary goal of the HCC Communications under the Global Health Advocacy Incubator project remains to tackle childhood obesity and by extension non-communicable diseases (NCDs) through healthy food environments across the Caribbean with a focus on Barbados and Jamaica. This has been achieved through the development and implementation of communication and advocacy campaigns, guided by a strategic plan to reach target audiences including policymakers, the media and lay-persons. Our markers of success have been grounded in regional governments policy readiness and implementation.

The HCC continues to communicate with various target audiences through several channels. These include social media including WhatsApp, Instagram, Facebook, X formerly known as Twitter, YouTube, LinkedIn and digital, including our website, email blasts, RoundUp newsletter, and our webinars. The HCC has engaged both traditional and online media in our efforts to reach our target audiences. The media, being one of our primary audiences we have engaged through our webinars, hang-outs, one-on-one meetings, training sessions, sensitisations and now through the sponsored Caribbean Media Awards.

The Healthy Caribbean Coalition (HCC) expanded its awards this year, to include a Healthy Nutrition Food Policy Award under two (2) themes; Television and Print for the 35th National Gas Company (NGC) Caribbean Media Awards (CMA) of the Caribbean Broadcasting Union (CBU). This activity culminated the 55th Caribbean Broadcasting Union’s Annual General Assembly, which took place in Placencia Belize. The Awards recognizes the work of the media produced and published in 2023. Following the criteria, nominations were released in June 2024. Nestled in the Umaya Hotel, the Awards took place on the night of Tuesday August 13th, 2024. The Nation Publishing Company, having coped its first ever CMA, was awarded in the print category and the Barbados Government Information Service (BGIS) emerged the winner under the television themed category. Special mention was given to RJR Gleaner Communications Group (Print Themed Award).

The event was live telecast hosted by Great Belize Productions Limited – Channel 5. Presentations, Trophies and Certificates were made in fifty-five (55) categories. A record number of these – twenty-four (24) were themed categories supported by category sponsors including:

  • UNDP CariSECURE2.0
  • Healthy Caribbean Coalition (HCC)
  • The Caribbean Community Climate Change Centre
  • The Sagicor Financial Company Limited
  • The Caribbean Development Bank Basic Needs Trust Fund
  • The Nature Conservancy Caribbean Division
  • The Partnership Initiative for Sustainable Land Management
  • SAEDI Consulting Limited

The organisation with the largest number of wins was RJR Gleaner Communications Group from Jamaica with sixteen (16) awards and four (4) special mentions across its media services. Great Belize Productions – Channel 5 was second with eight (8) wins and two (2) special mentions. Trinidad and Tobago was well represented with Trinidad Express fielding five (5) awards and garnering four (4) special mentions. TTT Limited received four (4) awards and a special mention. The Guardian Group was successful in five (5) categories with two awards for CNC-3; two (2) special mentions for television service and one (1) for the print-arm-Guardian newspaper.

The theme for this year’s Annual General Assembly was the Media and the Environment. This theme, being quite expansive covers key areas of interest of the HCC including the food environment in which a healthy and nutritious environment supported by healthy nutrition food policies allows individuals to grow, live, learn and thrive and climate change; which impacts heavily on the kind of food environment we have at our disposal. Food security relies heavily on and is impacted by climate change.

  • The BGIS award – “Grow Green Barbados: Episode 3 – Organic Farming” – Aisha Reid, Mikul Elcock, David Bynoe, Esther Jones,  KathyAnn Husbands
  • Nation Publishing Company (Barbados) It’s War – Donna Sealy
  • Special Mention: RJR Gleaner Communications Group (Jamaica) – “Hungry Belly Children Can’t Learn” – Andre Williams

The HCC will also sponsor two (2) journalists for the 2024 awards (36th CMA) which has been announced will take place in Barbados in August 2025. This will be promoted at the Healthy Food Policy Virtual Sensitisation for Media Managers, Journalists and Partners in October 2024. The HCC was represented by Communications Officer Sheena Warner-Edwards in Belize, throughout the General Assembly. Participants experienced the culture of Belize through the food and the people. Both the Opening Ceremony and the Awards were streamed from Channel 5across HCCs social media channels.

Here are some photos from the event.

https://www.youtube.com/watch?v=JOH3Ow9mg_w

CBU Media Monitoring

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7 months 2 weeks ago

Latest, News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Can detection of breast Arterial Calcification during mammography help Assess CV Risk in Women?

A recent study published in the American Journal of Preventive Cardiology highlighted a significant challenge in accurately stratifying cardiovascular (CV) risk in females. Traditional models often miss a substantial proportion of at-risk women, particularly the individuals without obvious symptoms or standard risk indicators.

However, breast arterial calcifications (BAC) can be identified during routine mammography and have been emerged as independent prognosticators of cardiovascular risk. The study investigated how BAC interacts with coronary artery disease profiles as assessed by computed tomography (CT) by focusing on the implications of BAC 0 (absence of BAC) and its relationship with coronary artery calcification (CAC) scores, the severity of coronary stenosis, and the presence of high-risk plaques (HRP).

The study included a total of 443 consecutive female patients who underwent both mammography and coronary CT angiography (CTA) for clinical indications within a year. The patients were divided into 3 age groups: under 55 years, 55-65 years, and over 65 years. This research analyzed the prevalence of BAC 0 and its correlation with CAC scores, specifically the individuals greater than 300 Agatston Units (AU), the severity of coronary stenosis (defined as obstructive disease with >50% stenosis) and the presence of high-risk plaques.

The results revealed significant age-related differences in the prevalence of BAC 0. Younger women (under 55 years) with BAC 0 were highly unlikely to have a severe CAC score (>300 AU), with only 0.82% of these women falling into this high-risk category. However, this protective effect of BAC 0 diminishes with age. The prevalence of high CAC scores in the individuals with BAC 0 jumps significantly in women over 65, with a 16.58-fold increase in risk when compared to younger women. Women aged 55-65 also showed a marked increase in high CAC scores, with 12.1% affected.

When examining obstructive coronary disease, the study found that 18.2% of women with BAC 0 had significant coronary stenosis (>50% blockage). Again, this risk was age-dependent: 10.7% in women under 55, 14.7% in those aged 55-65, and 29.9% in women over 65 years. While BAC 0 seemed somewhat protective against severe CAC in younger women, it did not rule out the presence of obstructive coronary disease or high-risk plaques across all age groups. The correlation between BAC, CAC, and CAD-RADS (a scoring system for coronary artery disease severity) was weak, with no significant association between BAC and the presence of high-risk plaques.

The study illuminates that while BAC 0 may help rule out severe coronary calcification in women under 55, it does not reliably predict the absence of obstructive coronary disease or high-risk plaques in older women. Overall, this finding has important implications for primary prevention strategies by suggesting that reliance on BAC 0 alone in cardiovascular risk assessment may leave a significant proportion of women at risk, particularly the women over 55 years old.

Source:

Deeg, J., Swoboda, M., Bilgeri, V., Lacaita, P. G., Scharll, Y., Luger, A., Widmann, G., Gruber, L., & Feuchtner, G. M. (2024). Does the absence of breast arterial calcification (BAC 0) rule out severe coronary artery disease? A computed tomography angiography study. In American Journal of Preventive Cardiology (Vol. 19, p. 100724). Elsevier BV. https://doi.org/10.1016/j.ajpc.2024.100724

7 months 2 weeks ago

Cardiology-CTVS,Cardiology & CTVS News,Top Medical News

PAHO/WHO | Pan American Health Organization

La OPS y la Oficina Internacional para la Epilepsia buscan elevar la epilepsia como prioridad de salud en las Américas

PAHO and International Bureau for Epilepsy seek to make epilepsy a health priority in the Americas

Oscar Reyes

6 Sep 2024

PAHO and International Bureau for Epilepsy seek to make epilepsy a health priority in the Americas

Oscar Reyes

6 Sep 2024

7 months 2 weeks ago

Health – Dominican Today

Ministry of Health enhances plans for pandemic and respiratory epidemic response

Santo Domingo.- The Ministry of Health, supported by the Pan American Health Organization (PAHO) and other health sector partners, is enhancing the Dominican Republic’s ability to handle health emergencies, particularly those involving respiratory viruses.

Santo Domingo.- The Ministry of Health, supported by the Pan American Health Organization (PAHO) and other health sector partners, is enhancing the Dominican Republic’s ability to handle health emergencies, particularly those involving respiratory viruses.

To achieve this, the Ministry of Health, through its Epidemiology Department, conducted a workshop titled “Framework of National Programs for the Prevention and Control of Diseases Caused by Respiratory Viruses with Epidemic and Pandemic Potential.” The workshop involved collaboration with the National Health Service (SNS), the General Directorate of Livestock, and the General Directorate of Medicines, Food, and Health Products (Digemaps).

The workshop addressed the current status and gaps in the prevention and control of respiratory viruses, aiming to bolster surveillance, expand policy measures, strengthen epidemic response, and improve risk communication and community involvement. It sought to create a unified national strategy for managing influenza and other respiratory viruses with epidemic or pandemic potential.

Key health sector stakeholders, including the Association of Private Clinics (Andeclip), the Dominican Society of Pulmonology, USAID, Promese/Cal, and the National Public Health Laboratory Dr. Fernando A. Defilló, participated in the three-day training, which focused on technical cooperation and response strategies for respiratory diseases.

7 months 2 weeks ago

Health

Health – Dominican Today

Abinader: Haiti crisis straining Dominican Republic’s migration, health, and education systems

Santo Domingo.- President Luis Abinader addressed the Haitian crisis’s impact on the Dominican Republic during a recent meeting with U.S. Secretary of State Antony Blinken. Abinader highlighted the strain the situation places on the Dominican Republic’s migration, health, and education systems.

Santo Domingo.- President Luis Abinader addressed the Haitian crisis’s impact on the Dominican Republic during a recent meeting with U.S. Secretary of State Antony Blinken. Abinader highlighted the strain the situation places on the Dominican Republic’s migration, health, and education systems.

At a press conference, Abinader noted that approximately 6.5% of the Dominican Republic’s students, around 147,000, are of Haitian nationality. He also revealed that Haitian migrants account for 14% of hospitalizations and 34% of births in public hospitals, a situation he claimed is unprecedented in global health systems.

Abinader expressed concern over the increased migratory pressure resulting from the crisis, which affects public services and poses security risks. He emphasized the need for additional support from the multinational security support mission (MCS) and resources to strengthen the UN trust fund. The President also highlighted the importance of renewing the MCS mandate in October.

He reiterated the Dominican Republic’s commitment to working with the United States on regional security and stability, while acknowledging differences in perspectives on certain issues.

7 months 2 weeks ago

Economy, Health, Local

Health | NOW Grenada

Grenadians in Barbados raise funds for Alexis Simon

5K Run & Walk tomorrow, Saturday, 8 September 2024, at the Garrison, Barbados — fundraiser by Grenadians in Barbados for a prosthetic arm for Alexis Simon, a survivor of the tragic events of 19 October 1983 in Grenada

7 months 2 weeks ago

Community, Health, History, PRESS RELEASE, 19 october 1983, alexis simon, amputee, barbados, barbados community foundation, bcf, fort george, fort rupert, fundraiser, grenadians in barbados, maurice bishop, prosthetic, shireene mathlin-tulloch

Health | NOW Grenada

Access available to 2 playing fields in Carriacou

Lauriston Mini Stadium field, and the turf wicket and main field at Dover Playing Field are available for recreational activities in Carriacou

View the full post Access available to 2 playing fields in Carriacou on NOW Grenada.

Lauriston Mini Stadium field, and the turf wicket and main field at Dover Playing Field are available for recreational activities in Carriacou

View the full post Access available to 2 playing fields in Carriacou on NOW Grenada.

7 months 2 weeks ago

Carriacou & Petite Martinique, Environment, Health, lifestyle, PRESS RELEASE, Weather, dover playing field, grenada solid waste management authority, gswma, hurricane beryl, kerryne james, lauriston mini stadium, ministry of carriacou and petite martinique affairs

Health | NOW Grenada

Bilateral Training Course: Medical Technology for Grenada

Completed applications must be submitted to the Department of Public Administration (DPA) by email at registry@dpa.gov.gd by 16 September 2024

Completed applications must be submitted to the Department of Public Administration (DPA) by email at registry@dpa.gov.gd by 16 September 2024

View the full post Bilateral Training Course: Medical Technology for Grenada on NOW Grenada.

7 months 2 weeks ago

Education, Health, PRESS RELEASE, bilateral training course, china, department of public administration, gis, medical technology

Health Archives - Barbados Today

New staffing at QEH to improve patient care

Chief Operating Officer of the Queen Elizabeth Hospital (QEH) Dr Christina Grenidge is expecting major improvements at the healthcare institution as it prepares to welcome significant staffing enhancements aimed at boosting efficiency and improving patient care.

 

Chief Operating Officer of the Queen Elizabeth Hospital (QEH) Dr Christina Grenidge is expecting major improvements at the healthcare institution as it prepares to welcome significant staffing enhancements aimed at boosting efficiency and improving patient care.

 

The strategic additions include the roles of patient safety officers, a service improvement manager, nurse practitioners and clinical nurse specialists.

 

Greenidge detailed the transformative potential these roles are expected to bring to the hospital. Particularly, the introduction of nurse practitioners is seen as a pivotal move to enhance service delivery in critical areas such as outpatient clinics and emergency rooms.

 

“They can work in two very important areas of the hospital — outpatient clinics and the emergency room,” Greenidge told The Pulse radio shown earlier this week. She emphasised the need for clear guidelines on their scope of practice within Barbados, noting their established effectiveness in other health systems like in the United States, where they prescribe medications and manage patient care plans in collaboration with physicians.

 

“Nurse practitioners have made a difference in primary care, helping patients with chronic conditions live healthier lives. They will undoubtedly play an integral role here at QEH,” she stressed.

 

Moreover, the role of patient safety officers is highlighted as crucial in maintaining and elevating safety standards within the hospital. These specialists will be tasked with overseeing all aspects of patient safety, from monitoring wait times to ensuring compliance with medical care plans.

 

“Patient safety is at the core of quality healthcare management. These officers will play a key role in monitoring and ensuring adherence to safety protocols, which is vital for patient outcomes,” stated Greenidge, herself a certified patient safety officer.

 

This staffing overhaul is part of a broader initiative to address the pressing healthcare professional shortage that is not only a local but a global issue, affecting many countries including the United States and Canada. To this end, the Barbados government plans to create 142 new registered nurse positions over the next two years and is looking to recruit internationally, including from Ghana.

 

The comprehensive plan to reform the nation’s healthcare system was announced by Prime Minister Mia Mottley at a recent Barbados Labour Party meeting at the St Christopher School in Christ Church South.

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7 months 2 weeks ago

Health, Local News

Health Archives - Barbados Today

Cut it out: Dead pig in bin sparks SSA outrage

A shocking discovery in Christ Church has left sanitation officials fuming. On Thursday, a dead pig was found dumped in a public waste bin in Silver Sands, prompting a stern rebuke from the Sanitation Service Authority (SSA).

 

A shocking discovery in Christ Church has left sanitation officials fuming. On Thursday, a dead pig was found dumped in a public waste bin in Silver Sands, prompting a stern rebuke from the Sanitation Service Authority (SSA).

 

“Cut it out,” declared Carl Padmore, public relations officer for the SSA, in response to the incident. He described the situation as “quite disturbing” and “extremely disrespectful”.

 

The carcass was discovered after a concerned resident alerted the authorities. While smaller animals have become a common sight in bins, this marks a disturbing escalation, according to Padmore.

 

“We have seen things like chickens already, we would have seen things like animal faeces, but to see this here is extremely disturbing. It shows a lack of respect,” Padmore told Barbados TODAY. “This is the biggest of the animals we have seen thus far, and this is taking disgust to a very high level.”

 

The SSA spokesman emphasised that proper channels exist for the disposal of dead animals, including a dedicated SSA hotline and services provided by the Ministry of Health. The matter has been reported to both the police and health authorities, and Padmore hopes for swift action against the perpetrator.

 

“We are going to go all out to investigate this matter, and we are hoping that the guilty person can be dealt with,” he said. “Now, we are not the law, we are not the Ministry of Health, but we will do all in our power to provide them with the necessary information, and if there is a possibility of any type of action, the SSA will support that because this really has gone too far and we can’t tolerate this.”

 

This latest incident highlights an ongoing issue faced by sanitation workers. Padmore revealed that employees regularly complain about foul odours emanating from bins, suspecting animal remains. In some cases, even human waste has been discovered.

 

“The workers are annoyed and they have a right to be, when this type of action is happening,” Padmore said. “These are humans removing your waste, and they should be treated with a high level of respect.”

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7 months 2 weeks ago

Health, Local News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Medical Bulletin 06/ September/ 2024

Here are the top medical news for the day:

Danish Study Finds Air Pollution Impacts Male Fertility, and Traffic Noise with Female InfertilityA Danish study published in the The BMJ , has revealed that long term exposure to fine particulate matter (PM2.5) air pollution is linked to a higher risk of infertility in men, whereas road traffic noise is linked to a higher risk of infertility in women over 35.Infertility is a major global health problem affecting one in seven couples trying to conceive. Several studies have found negative links between particulate air pollution and sperm quality and success after fertility treatment, but results on fecundability (the likelihood of conceiving) are inconsistent, and no studies have investigated the effects of transport noise on infertility in men and women.To address this uncertainty, researchers set out to investigate if long term exposure to road traffic noise and fine particulate matter (PM2.5) air pollution was associated with a higher risk of infertility in men and women.Their findings are based on national registry data for 526,056 men and 377,850 women aged 30-45 years, with fewer than two children, cohabiting or marriedYearly average particulate matter (PM2.5) concentrations and road traffic noise levels at each participant’s address (1995-2017) were calculated, and infertility diagnoses were recorded from the national patient register. Infertility was diagnosed in 16,172 men and 22,672 women during an 18-year follow-up period (an average of just over 4 years). After adjusting for several potentially influential factors including income, education level, and occupation, exposure to 2.9 µg/m3 higher average levels of PM2.5 over five years was associated with a 24% increased risk of infertility in men aged 30-45 years. PM2.5 was not associated with infertility in womenExposure to 10.2 decibels higher average levels of road traffic noise over five years was associated with a 14% increased risk of infertility among women older than 35 years. Noise was not associated with infertility among younger women (30-35 years).Reference: Sørensen, M., Poulsen, A. H., Nøhr, B., Khan, J., Ketzel, M., Brandt, J., Raaschou-Nielsen, O., & Jensen, A. (2024). Long-term exposure to road traffic noise and air pollution and risk of infertility in men and women: Nationwide Danish cohort study. BMJ (British Medical Journal). https://doi.org/10.1136/bmj-2024-080664Clinical Trial finds Adding Certain Anticoagulant Drugs ineffective for Stroke Patients Stroke patients who survive a blood clot in the brain’s blood vessels are prone to developing new blockages during their recovery periods, even if they receive vessel-clearing interventions. In an effort to avoid further clots, doctors at 57 sites around the U.S. tested a possible solution: the addition of anti-coagulant drugs to medicine that dissolves blood clots.But results from the clinical trial, led by Opeolu Adeoye, MD, head of the Department of Emergency Medicine at Washington University School of Medicine in St. Louis, indicate two such drugs did not improve outcomes.The findings are published in The New England Journal of Medicine.“We’re a little disappointed in the results,” said Adeoye, who is also the BJC HealthCare Distinguished Professor of Emergency Medicine. “But it’s meaningful to optimal patient care that we’ve answered the question definitively. Neither of the drugs helps prevent further clots.”The goal of the Multi-arm Optimization of Stroke Thrombolysis (MOST) clinical trial that Adeoye led was to test the efficacy of adding argatroban, a blood thinner, or eptifibatide, which inhibits blood platelets from sticking together, to the routine intravenous thrombolysis treatment.The trial closed the chapter on this potential use of these medications, but Peter Panagos, MD, professor of emergency medicine and co-author on the study, said that efforts like these inform future advances in medicine, including potential new anti-coagulant treatments.“Without negative trials, we would not know how to design new trials,” Panagos said. “Future success is built upon the hard work of previous research effort.”Physicians do not have a lot of treatment options for patients who experience a stroke. Some patients undergo a procedure to remove the clot. Others receive intravenous thrombolysis to relieve the affected blood vessel through clot-dissolving medication delivered to the bloodstream. A number of patients receive both interventions.“Even with those treatments, over half of patients still have a significant disability three months after their stroke," said Adeoye, who treats patients at Barnes-Jewish Hospital and Missouri Baptist Medical Center and also provides stroke telemedicine consultation. "After you give the thrombolysis, the clot can re-form, which contributes to the stroke worsening or persisting.”Preventing these clots with an additional treatment of anti-coagulant drugs seemed like a promising idea, especially as there are FDA-approved medications that earlier studies had suggested could be effective.In the MOST trial, patients were randomly assigned to receive either argatroban, eptifibatide or placebo. Adeoye explained that the study had checkpoints built in to ensure that treatment outcomes were meeting efficacy thresholds in order to continue. The first checkpoint was set at 500 patients, which the team reached in 2023.“When we looked at the data, it was readily apparent that neither drug was going to come anywhere close to our threshold,” he said.In fact, the probability that either drug was helpful was less than 1%. Worse still, argatroban and eptifibatide were linked to greater incidences of disability and mortality within the three-month post-treatment observation window.This correlation was not necessarily alarming; the safety monitors on the project found that the deaths appeared to have causes unrelated to the medications. The lack of improvement noted with the medications compared with what was noted with the placebo was reason enough to call off the trial.Reference: Adeoye O, Broderick J, Derdeyn CP, Grotta JC, Barsan W, Bentho O, Berry S., Concha M, Davis I, Demel S, Elm J, Gentile N, Graves T, Hoffman M, Huang J, Ingles J, Janis S, Jasne AS, Khatri P, Levine SR, Majjhoo A, Pancioli A, Panagos P, Pizzella S, Ranasinghe T, Sabagha N, Sivakumar S, Streib C, Vagal A, Wilson A, Wintermark M, Yoo AJ, Barreto AD. Adjunctive intravenous argatroban or eptifibatide for ischemic stroke. The New England Journal of Medicine. Sept. 4, 2024.Insulin and Metformin shows promise in treatment of Diabetic Foot Ulcer: Research FindsResearchers from Michigan State University and South Shore Hospital in Massachusetts have uncovered a connection between two common diabetes drugs injectable insulin and metformin identified in wound exudates of diabetic foot ulcers, which may improve their healing.Research published in ACS Pharmacology & Translational Science has found that wound exudate the fluid the body sends to an injury site—contains metformin in patients who take the medication orally.The researchers then explored metformin’s relationship to insulin. They found that for patients who take both insulin injections and oral metformin, the amount of metformin found in wounds significantly increases. It was previously believed that there was no interaction between insulin and metformin.Diabetic foot ulcers (DFUs) pose a significant challenge in wound care due to their chronic nature and impaired healing processes. This study examines the biogenic amines and small molecule metabolites present in diabetic foot ulcer wound exudates to identify their potential roles in wound healing.“Until now, pharmacological studies had not found an interaction between insulin and metformin,” said Morteza Mahmoudi, an associate professor in the Department of Radiology and Precision Health Program at the MSU College of Human Medicine.. “Our study shows that there could be at least an indirect role of consuming both insulin and metformin in a way that metformin can end up in a wound area where it enhances the body’s capacity to heal.”Reference: Gould, L., & Mahmou, M. (2024). Analysis of biogenic amines and small molecule metabolites in human diabetic wound ulcer exudate. ACS Pharmacology & Translational Science. Study Finds Heavy Metal Cadmium May Linked To Memory IssueThe heavy metal cadmium, which is found in the air, water, food and soil, is known to cause health problems. A new study published in Neurology examined if thinking and memory skills were associated with cadmium exposure.They found no association when they looked at the group as a whole. However, when looking at Black and white people separately, it found cadmium may be tied to problems with thinking and memory skills in white people. The study found no such association in Black people. The study does not prove that cadmium causes memory problems in white people; it only shows an association.Cadmium is a highly toxic heavy metal that enters the body mainly through cigarette smoking, breathing polluted air and food. It is released into the environment through industrial and agricultural activities.The study involved 2,172 people with an average age of 64 and no problems with thinking or memory skills. Black people made up 39% of the participants and white people made up 61%. Levels of cadmium in the urine were tested at the beginning of the study. Participants took tests of thinking and memory skills every year and were followed for an average of 10 years.During that time, 195 people developed cognitive impairment. When researchers looked at the overall group, they found no association between cadmium levels and cognitive impairment. However, when they looked at Black and white participants separately, they found that white people with high levels of cadmium were more likely to develop cognitive impairment. They found no association in Black people.With participants divided into two groups based on cadmium levels, white people with high levels were twice as likely to develop cognitive impairment as those with low levels, even after adjusting for other factors that could affect cognitive impairment, such as physical activity, alcohol use and education. A total of 9.2% of those with high levels developed thinking and memory problems, compared to 6.7% of those with low levels.New Published Guidelines For Helicobacter Pylori Suggest Change to Treatment RecommendationsThe American Journal of Gastroenterology has published a new guideline on the treatment of Helicobacter pylori (H. pylori) infection.H. pylori is a bacterium that infects over half the people in the world, though most are asymptomatic. It can cause dyspepsia, peptic ulcer disease and gastric cancer. A previous guideline was published in 2017. It had maintained the recommendation of a proton pump inhibitor-clarithromycin triple therapy as the primary treatment option.In the new guideline, the number one recommendation for treatment-naïve patients is bismuth quadruple therapy. That treatment typically includes a PPI, tetracycline, bismuth and nitroimidazole for 14 days. “We were already recommending that healthcare providers move away from PPI triple therapy in 2017 because of increasing problems with chloromycetin resistance amongst H. pylori strains in the United States,” corresponding author of the guideline, William D. Chey said. “Despite that recommendation, PPI triple therapy still dominates first-line therapy prescriptions for H. pylori patients in the United States. In this newest iteration of the guideline, we are very clear to say that in essentially all circumstances you should not be prescribing PPI triple therapy, and you should be instead using bismuth quadruple therapy or one of the other suggested treatment options.”A third option consists of a new, highly potent drug which blocks stomach acid production called vonoprazan combined with the antibiotic amoxicillin.The guideline makes 12 total treatment suggestions for patients in a variety of different situations. The number two recommendation for treatment-naïve patients—after bismuth quadruple therapy—is rifabutin triple therapy (a PPI, rifabutin and amoxicillin.)Besides the move away from PPI triple therapy, another change from the 2017 guideline is the discussion of increasingly available molecular testing for antibiotic susceptibility. The guideline also outlines future research priorities, such as identifying which individuals would most benefit from H. pylori testing to prevent gastric cancer and evaluating newly FDA-approved regimens for persistent infections.Reference: Chey, W. D., Howden, C. W., Moss, S. F., Morgan, D. R., Greer, K. B., Grover, S., & Shah, S. C. (2024). ACG clinical guideline: Treatment of Helicobacter pylori infection. The American Journal of Gastroenterology, 119(9), 1730-1753. https://doi.org/10.14309/ajg.0000000000002968

7 months 2 weeks ago

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