Sunbathing for just ONE DAY may increase your risk of heart disease - and stop the body fighting infections, study suggests
Researchers studied residents of Lousville Kentucky in the summer heat. They found going from no heat to moderate heat was enough to trigger compounds known to raise heart risk.
Researchers studied residents of Lousville Kentucky in the summer heat. They found going from no heat to moderate heat was enough to trigger compounds known to raise heart risk.
1 year 1 month ago
Medical News, Health News Latest, Medical News Today - Medical Dialogues |
MP Nursing College Affiliation Scam: HC Allows Affected Students to Appear in Exams
Jabalpur: Granting relief to thousands of nursing students who had been admitted to deficient and unsuited colleges, the Madhya Pradesh High Court has allowed them to participate in the examination for the previous academic sessions.
However, the HC Division bench of Justices Sanjay Dwivedi and Achal Kumar Paliwal clarified that this arrangement and benefit would be given only as a one-time measure and if the students fail to clear the exam, no further benefit would be given to them.
"These applications are allowed to the extent that not only the students, who are before this Court, but other students of unsuited colleges shall be allowed to participate in the examination as set-forth," the bench further added.
These concerned colleges were depicted as 'deficient' in the report of the Central Bureau of Investigation (CBI) submitted in deference to the order of the High Court.
Meanwhile, by filing an interim application, these 'deficient' colleges expressed their grievances regarding the Court order directing the constitution of three-member expert committee and shifting of students of deficient colleges to other colleges with an intent to evade academic loss to the students.
While considering their plea, the HC observed that shifting the students to other colleges would cause them hardship as contended by the intervenor deficient colleges. It had been contended that the students would lose 3-4 years if they were not allowed to participate in the examination.
Also Read: High Court directs State to close 70 Bogus Nursing Colleges
Responding to their pleas, the Court ordered, "We find it but obvious that shifting of students of colleges which cured the defects, would necessarily add to their hardship. Ergo, we modify the order to the extent that the students of colleges enlisted as deficient shall be allowed to participate in the examination. At the same time, the Committee will see whether the colleges have cured the deficiencies to get the recognition and affiliation for future years or not. It is made clear that this order would not only govern the students of deficient colleges categorised by CBI, but would also be available for the colleges which have not come to threshold of this Court so as to truncate the exercise of filing more applications for the same purpose. These applications are accordingly allowed with the above modification in the order dated 13.02.2024."
As per the latest media report by Live Law, previously while considering the pleas challenging the legality of granting recognition and affiliation to nursing colleges in the State, the HC bench had set up a three-member committee headed by Retired Justice Rajendra Kumar Shrivastava. The panel was tasked with supervising the progress of 74 colleges found to be deficient with minimal curable deficiency.
The Central Bureau of Investigation (CBI) inspected 308 colleges out of 364 colleges in compliance with the court order, barring 66 nursing colleges having interim protection from the inspection by the Apex Court. Among these 308 colleges, 65 colleges were found to be 'unsuitable' and 74 colleges were found to possess curable deficiencies. Accordingly, CBI submitted its report in a closed envelope on 17.01.2024.
Previously, the Court on 08.02.2024 had clarified that none of the students who got admitted to these 'unsuitable' colleges were entitled to re-accommodation in other colleges. Back then, the court had reasoned that it was the duty of the students to ensure that the colleges met the minimum standards of medical education by relying on the order in the case of Re Committee of Management Anuragi Devi Degree College & Anr. v. State of Uttar Pradesh & Anr.
Thereafter, the students of these unsuitable colleges filed interim applications before the HC bench and argued that they could not be compared to the graduate students who were aggrieved in the case of Re Committee of Management Anurag Devi.
Agreeing with this argument, the court noted "...these students are not graduates and their mental status cannot be equated with the students who are graduate nor are they come in the circumference of students whom the Supreme Court had repelled to favour."
Modifying its order, the bench granted relief to the students allowing them to appear in the exam and observed,
"Thus, we are of the opinion that the order dated 08.02.2024 is modified to the extent that students of unsuited colleges shall also be permitted to participate in the examination, but this arrangement and benefit would be a one-time-measure and if they do not clear the examination, no further benefit shall be given to them. These applications are allowed to the extent that not only the students, who are before this Court, but other students of unsuited colleges shall be allowed to participate in the examination as set-forth."
In their plea, the students also highlighted that they provided their services in the Government Health Centres during the COVID-19 outbreak. Acknowledging their contribution, the court noted, "On careful consideration of the documents made appendage to this application, it transpires that these students had borne the brunt of the responsibility when regular government staff took to their heels."
Further, the Court modified its previous order mentioning that the regularisation of Session 2023-24 mentioned in the order dated 13.02.2024 year shall be read as Session 2022-23 instead.
Emphasizing that the State Government will have the discretion to determine whether the academic session 2023-2024 must be declared as zero-year or not, the bench ordered, "Albeit, MPMSU has sent such proposal to the State Government but the State Government has not yet acted thereupon and now it is for the State to decide whether declaration of Session 2023-24 as zero-year is proper or not and if yes, then further sessions could be regularised or not. He accentuates that Nursing Council has already given its approval that last date of admission can be extended and as such declaration of zero-year would also cause great loss to the colleges which are otherwise found suitable."
"Thus, we deem it proper to keep the ball in the court of State Government to take decision eitherway on the proposal of MPMSU and accordingly, this court will give its verdict. For the present, Session 2023-24 mentioned in the order dated 13.02.2024 shall be read as Session 2022-23. Thus, we allow the suited colleges to start enrollment of students for the Session 2022-23. The decision with regard to Session 2023-24 shall be taken by this Court after the decision is taken by the State Government on the proposal made by MPMSU," it further mentioned.
Medical Dialogues had reported last year how the Madhya Pradesh Nursing Council, Bhopal had cancelled the affiliation of 19 nursing colleges for several allegations of irregularities including the appointment of fake teachers.
Last year, the CBI submitted its report on the alleged Nursing Colleges scam case to the Gwalior bench of the Madhya Pradesh High Court. Submitting the report, CBI mentioned that 50 per cent of the colleges were found to be operating fraudulently.
Further, the report also contained information about 140 out of 271 Nursing Colleges in the State. Taking note of the report, the HC bench had directed the Indian Nursing Council (INC) to match its data with CBI's data and present its report. Back then, the Court had also warned INC and the officials of medical colleges of an FIR in case of any tampering of data.
The issue of nursing colleges running without adhering to the prescribed norms was earlier being considered by the Gwalior bench of Madhya Pradesh High Court as well. Previously, taking stringent action against such nursing colleges, the Madhya Pradesh HC had directed the State and the Nursing Council to shut down 70 such bogus Nursing Colleges belonging to Gwalior-Chambal region.
To view the latest order by the MP HC, click on the link below:
https://medicaldialogues.in/pdf_upload/madhya-pradesh-high-court-234685.pdf
Also Read: Madhya Pradesh Nursing Council Cancels Affiliation of 19 Nursing Colleges
1 year 1 month ago
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Sitios de telesalud prometen una cura para la “menopausia masculina” a pesar de prohibiciones
Durante el boom de la telemedicina por la pandemia de covid-19, surgieron tiendas online que promocionaban la testosterona como remedio para las afecciones masculinas relacionadas con la edad, a pesar de las normas de la Administración de Drogas y Alimento
Durante el boom de la telemedicina por la pandemia de covid-19, surgieron tiendas online que promocionaban la testosterona como remedio para las afecciones masculinas relacionadas con la edad, a pesar de las normas de la Administración de Drogas y Alimentos (FDA) emitidas hace años que restringen este tipo de publicidad sobre “testosterona baja”.
En anuncios de Google, Facebook y otros medios, los sitios web de telemedicina sobre testosterona pueden prometer una solución rápida para la “lentitud” y la libido baja en los hombres. Pero los médicos dicen que no hay pruebas de su eficacia, y que es más probable que las causas del decaimiento masculino para el que se promociona la testosterona como solución sean las afecciones crónicas, una dieta inadecuada o un estilo de vida sedentario.
De hecho, los médicos piden precaución, y la FDA recomienda que todos los suplementos de testosterona lleven la advertencia de que pueden aumentar el riesgo de infarto de miocardio y accidente cerebrovascular.
Existen razones médicas válidas para tratar a algunos hombres con testosterona. La hormona existe como medicamento desde hace décadas, y entre los pacientes actuales se encuentran hombres con hipogonadismo, algunos transexuales que la utilizan para facilitar la transición física y, en ocasiones, mujeres con síntomas menopáusicos. También ha sido utilizada durante décadas por fisicoculturistas y atletas para aumentar su fuerza.
Sin embargo, los dispensarios en internet pueden exagerar la idea de lo que a veces se denomina “menopausia masculina”, para impulsar las ventas de inyectables potenciadores de la testosterona, muy rentables, ignorando a menudo las directrices de seguridad que deberían impedir el uso de la hormona en hombres sanos. Algunos de los sitios web se dirigen a veteranos militares.
“He visto anuncios en Internet que se pasan de la raya”, afirmó Steven Nissen, médico y director académico del Heart, Vascular, and Thoracic Institute de la Clínica Cleveland. “Para el estado de ánimo y la baja energía, recetar testosterona aporta poco o ningún beneficio. Están promoviendo la testosterona para indicaciones que no figuran en la etiqueta”.
Casi todos los sitios web sobre testosterona citan un estudio publicado en 2002 por científicos de los New England Research Institutes, que descubrieron que los niveles de testosterona caen un 1% al año en hombres mayores de 40 años. Stefan Schlatt, director del Centro de Medicina Reproductiva y Andrología de la Universidad de Muenster, en Alemania, dijo que los datos que respaldaban la estadística incluían a hombres mayores con una salud deteriorada cuyos niveles disminuían a causa de enfermedades.
“Los hombres sanos no muestran ese descenso”, señaló.
Ese estudio de 2002 dio lugar a una avalancha de anuncios de “baja T” en la televisión estadounidense, anuncios que más tarde fueron prohibidos por la FDA, en una sentencia de 2015 que acusaba a la industria farmacéutica de exagerar el fenómeno de la baja T para asustar a los hombres y hacerles comprar medicamentos.
Según otro estudio, el mercado de suplementos de testosterona se situó en $1,850 millones en 2023.
El diluvio de anuncios “ha alimentado la demanda de un producto en gran parte no cubierto, lo que permite altos márgenes de beneficio”, explicó Geoffrey Joyce, director de políticas de salud en el USC Schaeffer Center for Health Policy & Economics e investigador del National Bureau of Economic Research. “El motor principal es la demanda fabricada”.
Barbara Mintzes, profesora de política farmacéutica basada en la evidencia en el Centro Charles Perkins de la Universidad de Sydney, Australia, dijo que el bajo nivel de testosterona debería considerarse realmente como un signo de una enfermedad que necesita tratamiento. Mintzes dijo que la diabetes, las cardiopatías, la hipertensión, la obesidad, la exposición a sustancias químicas tóxicas como los PFAS y el estrés pueden reducir los niveles de testosterona.
Varios de los sitios web analizados por KFF Health News se presentan como revistas de noticias y fitness, con anuncios insertados en los artículos que dirigen a los lectores hacia formularios para pedidos de terapia de sustitución de testosterona, abreviada como TRT.
Los precios de la TRT oscilan entre $120 y $135 al mes, sin incluir los análisis de sangre iniciales por correo, que cuestan unos $60. Algunos sitios prometen aumentar la libido y reducir la grasa del estómago.
Por ejemplo, los anuncios de Male Excel en Google dicen que la TRT “mejora el estado de ánimo” y “restaura la vitalidad”. Y su sitio dice que el tratamiento con testosterona proporcionará “definición muscular”, “pérdida de peso”, “impulso explosivo”, “sueño más profundo” y “energía restaurada” por encima de un enlace a una evaluación gratuita en su plataforma de telesalud en línea.
Craig Larsen, director general de la empresa, no respondió a varios intentos de establecer contacto por teléfono y correo electrónico.
Tanto Male Excel como Hone Health se encuentran entre los sitios que se dirigen a los veteranos militares. Hone Health incluía un video de un veterano que afirmaba que un hospital del Departamento de Asuntos de Veteranos le había denegado el tratamiento con testosterona.
Saad Alam, CEO y cofundador de Hone, afirmó que su empresa es “conservadora” en el mercado. Dijo que Hone receta sólo a los hombres que son hipogonadales y les hace pruebas cada 90 días, a diferencia de otras empresas que operan sitios web de telesalud a las que calificó de “cazadoras de dinero”.
“Estoy de acuerdo en que los pacientes deben ser tratados por sus médicos. Pero el sistema de salud estadounidense no está en condiciones de atender a los hombres que tienen este problema, y algunos endocrinólogos prefieren tratar a pacientes que proporcionan mayores beneficios”, dijo Hone. “Por eso la gente acude a nosotros”.
Una forma popular de TRT es el cipionato de testosterona inyectable. Según la base de datos de precios de venta de Medicare, cuesta $0,027 por miligramo. Los proveedores en internet que venden el fármaco directamente a los consumidores en viales de 200 mg/mL por un precio medio de $129 al mes están cobrando el equivalente a $1,55 por miligramo, un margen de beneficio de más de 50 veces el precio promedio de Medicare.
Según un estudio de 2022, los sitios web de telesalud de TRT crean una forma de eludir a los médicos que se niegan a recetar la hormona. En ese estudio, Justin Dubin, urólogo del Memorial Healthcare System de Florida, se hizo pasar por un consumidor. Declaró tener un nivel de testosterona por encima de lo normal y manifestó su deseo de formar una familia, a pesar de que este tipo de terapia puede frenar la producción de esperma. Sin embargo, seis de las siete clínicas online de TRT le recetaron testosterona a través de un profesional médico.
“Y eso es preocupante”, afirmó Dubin. “La telemedicina ayuda a los hombres con hipogonadismo que podrían sentirse demasiado avergonzados para hablar de disfunción eréctil. Pero tenemos que hacer un mejor trabajo para entender lo que es una atención apropiada”.
Aun así, aunque la FDA no permite la comercialización off-label (la práctica de recetar medicamentos para un uso distinto par el que han sido aprobados), sí permite las recetas off-label.
El uso off-label de reemplazo de testosterona se ha convertido en algo común entre los veteranos. Y entre los militares masculinos que recibieron TRT en 2017, menos de la mitad cumplieron con las pautas de práctica clínica, según un informe del ejército estadounidense.
Phil Palmer, veterano del Cuerpo de Marines, de 41 años, que vive en las afueras de Charleston, Carolina del Sur, dijo que paga de su bolsillo los análisis de sangre y las recetas para una forma de testosterona de implante cutáneo y para el clomifeno, un medicamento que puede ayudar a contrarrestar la infertilidad masculina que es un efecto secundario del tratamiento con testosterona.
Palmer explicó que el tratamiento es algo que le atrae tanto a él como a otros veteranos que se enfrentan a las secuelas de haber servido en las fuerzas armadas.
“El entorno en el que servimos y los niveles de estrés tienen mucho que ver”, afirmó Palmer. “Estuvimos expuestos a pozos de quema tóxicos. El ejército no te enseña a comer bien: comíamos mucha comida procesada”.
En el ámbito médico, la TRT puede acelerar la recuperación de los soldados que tienen problemas de densidad ósea o lesiones de la médula espinal, indicó Mark Peterson, profesor de medicina física y rehabilitación en la Facultad de Medicina de la Universidad de Michigan. Pero, agregó, “para los hombres en el rango normal de T, el uso de una receta en línea para comprar testosterona para reducir la grasa del estómago puede ser contraproducente”.
Quienes la utilizan también se arriesgan a tener que tomar medicación de testosterona indefinidamente, porque la TRT puede hacer que el cuerpo deje de producir su propia hormona.
Palmer, que fundó una organización sin fines de lucro que ayuda a los veteranos a recuperarse a través del ejercicio, la nutrición y la tutoría, dijo que la medicación le ha sido útil, pero insta a sus compañeros veteranos a recibir atención médica en lugar de lo que él llamó sitios web de “bro science” que promocionan la testosterona. (La “bro science” surge cuando los relatos anecdóticos de personas que practican fisicoculturismo en el gimnasio se consideran más creíbles que la investigación científica)
“No se trata de una píldora mágica”, concluyó.
KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF—an independent source of health policy research, polling, and journalism. Learn more about KFF.
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PAHO and the Korea International Cooperation Agency join forces to improve access to health for migrants in Peru
PAHO and the Korea International Cooperation Agency join forces to improve access to health for migrants in Peru
Cristina Mitchell
20 Mar 2024
PAHO and the Korea International Cooperation Agency join forces to improve access to health for migrants in Peru
Cristina Mitchell
20 Mar 2024
1 year 1 month ago
Medical News, Health News Latest, Medical News Today - Medical Dialogues |
Understanding and Managing Small Intestinal Bacterial Overgrowth (SIBO) - Dr Bhuvan Shetty
Small intestinal bacterial overgrowth (SIBO) is a well-recognized cause of maldigestion and malabsorption. It is defined as “a disease in which the small bowel is abnormally colonized by an increased number and abnormal types of microorganisms".
This imbalance in the number of bacteria can disrupt the normal digestive process, leading to various symptoms. Early recognition of the symptom is crucial for effective treatment.
The human gut is inhabited by 1014 bacterial cells, with approximately 500 to 1,000 different bacterial species identified to date.
Risk Factors
The prevalence of SIBO among the general population is not known, but in most studies, SIBO has been detected anywhere from 0 to 20% of healthy controls.
1) Digestive Disorders Conditions like irritable bowel syndrome (IBS), Crohn's disease, celiac disease, and gastroparesis can disrupt the normal balance of bacteria in the small intestine.2) Anatomical Abnormalities Structural issues in the gastrointestinal tract, such as strictures, fistulas, or surgical alterations, can slow down the movement of food and create an environment where bacteria can overgrow.3) Medications Certain medications, such as proton pump inhibitors (PPIs), antibiotics, narcotic pain relievers, and immune-suppressing drugs, can disrupt the normal balance of bacteria in the gut, predisposing to SIBO.4) Low Stomach AcidReduced stomach acid levels, which can occur due to aging, stress, or the use of acid-suppressing medications, can allow bacteria to survive in the stomach and migrate to the small intestine.5) Impaired Motility Conditions that affect the normal movement of the digestive tract, such as diabetes, scleroderma, and intestinal pseudo-obstruction, can lead to bacterial overgrowth by slowing down the transit of food through the small intestine.6) Dietary Factors Diets high in carbohydrates, sugar, and refined foods can provide a favourable environment for bacteria to proliferate in the small intestine.7) Immune System DysfunctionConditions that weaken the immune system, such as HIV/AIDS, autoimmune diseases, and chemotherapy, can impair thbody's's ability to control bacterial populations in the gut, increasing the risk of SIBO.8) Age SIBO is more common in older adults, possibly due to age-related changes in digestive function and immune response.Symptoms The symptoms of SIBO are nonspecific, and their frequency and severity likely reflect both the degree of bacterial overgrowth and the extent of mucosal inflammation.
1) Patients usually present with
2) Loss of appetite
3) Abdominal pain
4) Nausea
5) Bloating
6) An uncomfortable feeling of fullness after eating
7) Diarrhoea
8) Unintentional weight loss
9) Malnutrition
Clinical Manifestation
1) Weight Loss
2) Steatorrhea or Increased Excretion of fat with faeces due to reduced absorption of fat by intestine
3) Vitamin/mineral deficiency like fat-soluble vitamins (A, D, E, K), Vitamin B12, Iron
4) Hyperproteinaemia
Diagnosis
Multiple Tests are available for diagnosing SIBO.
Breath tests are simple, non-invasive, patient-friendly methods for diagnosing bacterial overgrowth. The glucose hydrogen breath test is commonly used to measure hydrogen levels in the breath. Elevated levels indicate Small intestinal bacterial overgrowth.
Treatment
Mainstay of treatment includes reducing symptoms and restoring normal bacterial microbiota in the intestine.
1) Antibiotics: It helps to eradicate bacterial overgrowth and repletion of any nutritional deficiencies.
2) Probiotics: It helps to restore healthy gut bacteria and help maintain healthy gut health
3) Lifestyle modification: A key principle in managing SIBO is identifying and treating any predisposing factors using a combination of dietary, lifestyle, medical, and surgical therapies. Lifestyle measures include avoiding sugar, reducing NSAID use, and smoking cessation.
In conclusion, SIBO remains a widely prevalent diagnosis but is often overlooked. Early recognition of the symptoms and treatment helps improve the quality of life.
Disclaimer: The views expressed in this article are of the author and not of Medical Dialogues. The Editorial/Content team of Medical Dialogues has not contributed to the writing/editing/packaging of this article.
1 year 1 month ago
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Dr Reddys Labs unveils Versavo in UK for several types of cancers
Hyderabad: Dr Reddy's Laboratories Ltd., a global pharmaceutical
company, has announced the launch of Versavo (bevacizumab) in the United Kingdom (UK).
Hyderabad: Dr Reddy's Laboratories Ltd., a global pharmaceutical
company, has announced the launch of Versavo (bevacizumab) in the United Kingdom (UK).
Dr Reddy’s
Versavo is a (bevacizumab) biosimilar of Avastin and indicated for the treatment of several types of
cancers, including metastatic colorectal cancer, advanced non-squamous non-small cell lung cancer,
recurrent glioblastoma, metastatic renal cell carcinoma, advanced cervical cancer, ovarian cancer and
metastatic breast cancer.
Bevacizumab is the first antiangiogenic therapy proven to slow metastatic disease progression in patients with cancer. It is a humanized recombinant antibody that targets human vascular endothelial growth factor (VEGF), leading to deterred angiogenesis and tumor growth.
Versavo is the first Dr. Reddy’s biosimilar product to be approved and launched in the UK. It is available
in strengths of 100mg and 400mg single use vials.
Dr Reddy’s launched Versavo in India in 2019. Subsequently, Versavo was introduced in other
markets such as Thailand, Ukraine, Nepal, and Jamaica under the same brand name. In Colombia, the
product was launched under the brand name Persivia.
Dr Jayanth Sridhar, Global Head of Biologics at Dr Reddy’s, said, “The launch of Versavo in a
highly regulated market underscores our capability for global clinical development of high-quality
biosimilar products. Versavo is a potential treatment option for patients with different types of cancers.
This launch reinforces our commitment to bring more biosimilar and other critical biological products to
meet the unmet needs of patients, and strengthens our focus on oncology.”
Established in 1984, Dr Reddy’s Laboratories Ltd. is a global
pharmaceutical company headquartered in Hyderabad, India. Dr Reddys offers a portfolio of products and services
including APIs, generics, branded generics, biosimilars and OTC. Its major therapeutic areas of focus are gastrointestinal,
cardiovascular, diabetology, oncology, pain management and dermatology. Dr Reddys major markets include – USA, India, Russia & CIS
countries, China, Brazil and Europe.
Read also: Dr. Reddy's gets CDSCO panel Nod To market Omeprazole Delayed-release orally disintegrating tablets
1 year 1 month ago
News,Gastroenterology,Medicine,Nephrology,Neurology and Neurosurgery,Obstetrics and Gynaecology,Oncology,Pulmonology,Gastroenterology News,Medicine News,Nephrology News,Neurology & Neurosurgery News,Obstetrics and Gynaecology News,Oncology News,Pulmonolog
Medical News, Health News Latest, Medical News Today - Medical Dialogues |
USFDA nod to Johnson and Johnson EDURANT PED for certain pediatric patients living with HIV-1
Titusville: Johnson & Johnson has announced that the U.S. Food and Drug Administration (FDA) has approved EDURANT PED (rilpivirine) for the treatment of HIV-1 in combination with other antiretroviral therapies (ARVs) in treatment-naïve children (with HIV-1 RNA <100,000 copies/mL) at least 2 years of age and weighing at least 14 kg and less than 25 kg.
“Decades of experience with the global HIV epidemic have made it clear that new and improved treatment options are needed to support the diverse population of people living with HIV on their treatment journey,” said Penny Heaton, M.D., Global Therapeutic Area Head, Infectious Diseases and Vaccines at Johnson & Johnson. “While the population of young children living with HIV is small, additional treatment options remain key to ensuring that each person living with HIV can be matched to a treatment regimen that is right for them.”
The FDA’s decision is based on results from the PAINT (NCT00799864) and PICTURE (NCT04012931) studies in pediatric subjects, which showed that rilpivirine, in combination with other ARVs, effectively suppresses the virus in treatment-naïve (with HIV-1 RNA <100,000 copies/mL) pediatric patients. Rilpivirine can be administered to children at least 2 years of age and weighing at least 25 kg via standard 25 mg oral tablets (EDURANT) or new 2.5 mg oral tablets (EDURANT PED) that were developed to aid administration and weight-adjusted dosing for children.
EDURANT and EDURANT PED are a human immunodeficiency virus type 1 (HIV-1) specific, non-nucleoside reverse transcriptase inhibitor (NNRTI) indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in treatment naïve patients at least 2 years of age and weighing at least 14 kg with HIV-1 RNA less than or equal to 100,000 copies/mL.
Limitations of Use:
- More EDURANT treated subjects with HIV-1 RNA greater than 100,000 copies/mL at the start of therapy experienced virologic failure (HIV-1 RNA ≥50 copies/mL) compared to EDURANT treated subjects with HIV-1 RNA less than or equal to 100,000 copies/mL.
EDURANT is indicated in combination with VOCABRIA (cabotegravir), for short-term treatment of HIV-1 infection in adults and adolescents 12 years and older and weighing at least 35 kg who are virologically suppressed (HIV-1 RNA less than 50 copies/mL) on a stable regimen with no history of treatment failure and with no known or suspected resistance to either cabotegravir or rilpivirine.
Read also: Johnson & Johnson seeks USFDA nod for Tremfya for ulcerative colitis treatment in adults
1 year 1 month ago
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Cancer screening to match resources
SCREENING TESTS can help find cancer at an early stage, before symptoms appear. When abnormal tissue or cancer is found early, it may be easier to treat or cure. By the time symptoms appear, the cancer may have grown and spread and this can make...
SCREENING TESTS can help find cancer at an early stage, before symptoms appear. When abnormal tissue or cancer is found early, it may be easier to treat or cure. By the time symptoms appear, the cancer may have grown and spread and this can make...
1 year 1 month ago
Emerging biomarkers for early detection of colon cancer
COLORECTAL CANCER is a type of cancer that affects the colon (large intestine) or rectum. It is one of the most common types of cancer worldwide that can cause severe harm and death. The risk of colorectal cancer increases with age and in most...
COLORECTAL CANCER is a type of cancer that affects the colon (large intestine) or rectum. It is one of the most common types of cancer worldwide that can cause severe harm and death. The risk of colorectal cancer increases with age and in most...
1 year 1 month ago
Medical News, Health News Latest, Medical News Today - Medical Dialogues |
Psoriatic Arthritis Treatment with Apremilast effective and may Improve Patient Satisfactio: Study
A recent real-world study, the APPRAISE study unveiled the effectiveness, tolerability and patient satisfaction with apremilast treatment for individuals with psoriatic arthritis (PsA) which is a chronic autoimmune condition characterized by joint inflammation and skin lesions, affecting millions worldwide.
This research was conducted across multiple Canadian rheumatology clinics and enrolled a total of 102 adults with active PsA. They were prescribed apremilast between July 2018 and March 2020 and were followed for 12 months with visits recommended every four months to monitor the progress. The primary outcome measure focused on achieving remission or low disease activity defined by a Clinical Disease Activity Index for Psoriatic Arthritis (cDAPSA) score of 13 or less.
The results from this study revealed significant improvements in various markers of disease activity despite 44.1% of the patients discontinuing this study within 12 months. Importantly, 63.7%, 67.2%, and 53.8% of patients achieved cDAPSA remission or low disease activity at 4 months, 8 months, and 12 months, respectively.
The patients who continued the study expressed reduced joint inflammation, pain and psoriasis symptoms. Improvement in treatment satisfaction and patient-reported outcomes, including physical and mental well-being, were obvious over the 12-month period. Safety data indicated that apremilast was well-tolerated, with diarrhea, nausea, and migraine being the most common adverse events leading to discontinuation.
This study expressed positive outcomes of apremilast in real-world settings, by providing patients with effective relief from PsA symptoms and enhancing their overall quality of life. Overall, these findings contribute to the growing body of evidence that support the clinical effectiveness of apremilast in PsA management.
Reference:
Chandran, V., Bessette, L., Thorne, C., Sheriff, M., Rahman, P., Gladman, D. D., Anwar, S., Jelley, J., Gaudreau, A.-J., Chohan, M., & Sampalis, J. S. (2024). Use of Apremilast to Achieve Psoriatic Arthritis Treatment Goals and Satisfaction at 1 Year in the Canadian Real-World APPRAISE Study. In Rheumatology and Therapy (Vol. 11, Issue 2, pp. 443–455). Springer Science and Business Media LLC. https://doi.org/10.1007/s40744-024-00641-w
1 year 1 month ago
Orthopaedics,Orthopaedics News,Top Medical News
First Lady presents oncopediatric pavilion for child and adolescent care
Santo Domingo.- First Lady Raquel Arbaje, along with Carlos Bonilla, Minister of Housing and Buildings (MIVED), and Mario Lama, Director of the National Health Service, unveiled the new “Uniendo Voluntades Oncopediatric Pavilion” at the Rosa Emilia Tavarez National Cancer Institute (INCART).
Santo Domingo.- First Lady Raquel Arbaje, along with Carlos Bonilla, Minister of Housing and Buildings (MIVED), and Mario Lama, Director of the National Health Service, unveiled the new “Uniendo Voluntades Oncopediatric Pavilion” at the Rosa Emilia Tavarez National Cancer Institute (INCART).
This facility, equipped with cutting-edge medical technology for pediatric and adolescent cancer treatment, spans 2,273 square meters and includes 41 hospital beds, two operating rooms, an anesthesiology room, an intensive care unit, six pediatric offices, a nursing station, and a day hospital.
Arbaje emphasized that the pavilion not only aims to provide high-level therapeutic care and a pleasant physical environment for children, adolescents, and young adults but also prioritizes the human aspect of the project.
For the first time, the Uniendo Voluntades Oncopediatric Pavilion will offer specialized care to adolescents and young people up to 24 years old, with an exclusive protocol tailored to their needs.
Minister Carlos Bonilla expressed appreciation for the First Lady’s initiative in securing funding for the construction and equipment of the pavilion, highlighting her commitment to improving the quality of life for vulnerable Dominicans. He thanked her for involving MIVED in the project, which adhered to the highest national and international health standards.
Mario Lama, Director of the National Health Service (SNS), underscored the significance of the pavilion in providing timely and quality care to children affected by cancer, thanks to President Luis Abinader’s commitment to making it a reality. He commended the collaborative efforts of the First Lady and MIVED in achieving this milestone.
The new pavilion, a product of the Uniendo Voluntades initiative, aims to expand specialized services for children with cancer while also humanizing the therapeutic process and alleviating the emotional burden on patients and their families.
Designed by MIVED, the pavilion meets national and international standards that prioritize spaces conducive to the emotional well-being of pediatric patients.
Through her “Uniendo Voluntades” initiative, the First Lady secured non-refundable financial contributions for the construction and acquisition of equipment, facilitated by the Central American Bank for Economic Integration (CABEI).
1 year 1 month ago
Health
First poison center established in the country
Santo Domingo.- The Ministry of Public Health (MSP) and the Pan American Health Organization (PAHO) jointly announced the establishment of a toxicological center in the country on Monday. The primary objective of this center is to provide specialized assistance and management for cases of poisoning.
Santo Domingo.- The Ministry of Public Health (MSP) and the Pan American Health Organization (PAHO) jointly announced the establishment of a toxicological center in the country on Monday. The primary objective of this center is to provide specialized assistance and management for cases of poisoning.
According to a statement released by Public Health, the center will offer information, guidance, and specialized care for diagnosing and treating cases of poisoning. Additionally, it will conduct toxicological laboratory tests, develop programs for poisoning prevention and toxicovigilance, promote research on poisoning prevention and management, and manage mass poisonings by alerting health authorities for prompt decision-making and effective health responses in incidents involving chemical substances.
To initiate this initiative, an inter-institutional commission was formed by the Ministry of Public Health in collaboration with PAHO advisors. This commission analyzed the feasibility of implementing the center.
Health Minister Víctor Atallah met with PAHO representative Alba María Ropero to validate specific details for the immediate commencement of installation work. As part of the preparation process, visits were conducted to pre-selected institutions to assess their physical, technological, and personnel capabilities. This assessment aimed to develop a roadmap and define the stages for the center’s development.
Minister Atallah described the establishment of a poison center as an unprecedented milestone for the country. He emphasized the necessity of having tools to mitigate health damage resulting from various causes, including improper handling of chemicals and food.
Ropero Álvarez underscored the significance of the initiative in reducing poisoning incidents. He noted that toxicological centers have been established across Latin America and the Caribbean to address similar situations of exposure to chemical substances. While a previous attempt was made in the Dominican Republic in 2009, Ropero Álvarez expressed confidence that the current endeavor would succeed.
1 year 1 month ago
Health
Sodium intake and the kidneys
Reduce the amount of sodium you consume by cooking with local herbs and spices instead of salt
View the full post Sodium intake and the kidneys on NOW Grenada.
Reduce the amount of sodium you consume by cooking with local herbs and spices instead of salt
View the full post Sodium intake and the kidneys on NOW Grenada.
1 year 1 month ago
Health, PRESS RELEASE, grenada food and nutrition council, high blood pressure, hypertension, kidney stones, salt, sodium, spices
Dominican Embassy in Belgium’s initiative on mental health
Belgium.- As part of the International Women’s Day commemoration activities, the Dominican Embassy in Belgium and Luxembourg organized two special discussions on mental health tailored for the Dominican diaspora in these regions. These sessions were led by renowned Dominican psychiatrist and therapist, Alexandra Híchez.
Belgium.- As part of the International Women’s Day commemoration activities, the Dominican Embassy in Belgium and Luxembourg organized two special discussions on mental health tailored for the Dominican diaspora in these regions. These sessions were led by renowned Dominican psychiatrist and therapist, Alexandra Híchez.
Both events, held over the weekend of March 16-17, at the Beford Hotel in Brussels and the Hotel Royal in Luxembourg, focused on addressing the mental health challenges and concerns faced by the Dominican diaspora. The aim was to raise awareness about the importance of mental well-being for Dominican migrants residing in Brussels and Luxembourg, providing them with a platform to share their experiences and reflections on the topic.
During her presentations, Dr. Híchez provided valuable insights and practical advice to enhance emotional and psychological well-being, especially in the context of migration. She also discussed significant topics such as women’s empowerment and their importance in contemporary society, along with other psychosocial risk factors.
The events commenced with welcoming remarks from Ambassador Iván Ogando Lora, who expressed gratitude to all participants and Dr. Híchez for her enthusiastic commitment to conducting these discussions. Ambassador Ogando Lora emphasized the significance of addressing mental health issues within migrant communities, particularly among women, whose migration and adaptation to a new country often entail significant emotional and psychological challenges.
He underscored that these discussions are part of the ongoing commitment of the mission to support the hardworking Dominican community in Belgium and Luxembourg, particularly in crucial areas like mental health, which contribute to strengthening unity and solidarity.
These activities were made possible with the support of the Ministry of Foreign Affairs of the Dominican Republic (MIREX) and Air Europa. Special acknowledgment is extended to Mrs. Gloria Paniagua, Veridania Mercedes, and Mórela Segura of the Bedford Hotel for their cooperation in facilitating the events.
1 year 1 month ago
Health, World
Endometriosis - one of the top two underdiagnosed conditions in T&T - Trinidad Guardian
- Endometriosis - one of the top two underdiagnosed conditions in T&T Trinidad Guardian
- Endometriosis patient shares journey of pain and diagnosis Bay News 9
- Local doctors working to spread awareness about endometriosis ABC Action News Tampa Bay
- Burlington woman brings attention to endometriosis in women WFMYNews2.com
- Walter Reed Champions Women's Health During National Endometriosis Awareness Month TRICARE Newsroom
1 year 1 month ago
Cuando tu cobertura de salud dentro de la red… simplemente se esfuma
Sarah Feldman, de 35 años, recibió las primeras cartas amenazantes del Centro Médico Mount Sinai en noviembre pasado. El sistema hospitalario de Nueva York le advirtió que tenía problemas para negociar un acuerdo de precios con UnitedHealthcare, que incluye los planes de salud de Oxford, la aseguradora de Feldman.
“Estamos trabajando de buena fe con Oxford para alcanzar un nuevo acuerdo justo”, decía la carta, continuando con la frase tranquilizadora: “Sus médicos seguirán siendo parte de la red y debería mantener sus citas con sus proveedores”.
En los meses siguientes, llegaron una avalancha de comunicaciones sobre la disputa tanto del hospital como de la aseguradora. Pasaban de “tienes que preocuparte” a “no tienes que preocuparte'”, contó Feldman.
A fines de febrero, finalmente cayó la bomba: desde el 1 de marzo, el Mount Sinai ya no estaría en la red de la aseguradora de Feldman.
“De repente tuve que cambiar todos mis médicos, gran estrés”, dijo Feldman. Eso incluía no solo a un querido médico de atención primaria, sino también a un ginecólogo, un ortopedista y un fisioterapeuta.
Uno de los aspectos más injustos del seguro médico, en un sistema que a menudo parece diseñado para la frustración, es este: los pacientes solo pueden cambiar de seguro durante los períodos de inscripción abierta al final del año o cuando experimentan “eventos de vida” que califican para una inscripción especial, como un divorcio o un cambio de trabajo.
Pero los contratos de las aseguradoras con médicos, hospitales y farmacéuticas (o sus intermediarios, los llamados administradores de beneficios farmacéuticos) pueden cambiar abruptamente de la noche a la mañana.
Esto es particularmente irritante para los pacientes porque, ya sea que tengan cobertura a través de un empleador o compren un seguro en el mercado, generalmente eligen un plan en función de si cubre a sus médicos y hospitales preferidos, o a un medicamento costoso que necesitan.
Resulta que esa cobertura particular podría desaparecer en cualquier momento durante el término de la póliza.
Los consumidores están en riesgo, según un informe reciente de la Robert Wood Johnson Foundation, en la creciente guerra de precios entre grandes sistemas hospitalarios y mega aseguradoras en un mercado despiadado.
Estas disputas de contratos están aumentando rápidamente, el sitio web Becker’s Hospital Review cita 21 enfrentamientos entre aseguradoras y proveedores en el tercer trimestre de 2023, un aumento del 91% comparado con el mismo período el año anterior.
Por ejemplo, en septiembre pasado, los médicos de Baptist Health en Kentucky cortaron abruptamente la relación con los pacientes inscritos en los planes de Medicare Advantage de Humana, y los médicos de Vanderbilt Health en Tennessee rompieron los contratos lo hicieron con varios planes de Humana, en abril.
En ambos casos los pacientes desesperados tuvieron que buscar frenéticamente nuevos médicos dentro de la red en otros sistemas hospitalarios.
Y expertos predicen más cancelaciones de contratos en un mercado cruel. (las cancelaciones que ocurren dentro del período de inscripción, generalmente entre noviembre y enero por lo menos permite que los pacientes abandonados busquen un nuevo plan que cubra sus médicos y medicamentos).
“La respuesta humana correcta es que esto es horrible”, dijo Allison Hoffman, profesora de derecho de la Universidad de Pennsylvania, incluso si la práctica, por ahora, es “probablemente legal”.
Hoffman dijo que encontró una cláusula “enterrada” en la página 32 de su propio plan médico, de 60 páginas, que sugería que los contratos entre proveedores y aseguradoras pueden cambiar en cualquier momento.
Los reguladores estatales y federales tienen la autoridad para regular las redes de aseguradoras y podrían poner fin a la práctica, dijo Hoffman. Pero hasta ahora “no ha habido regulación federal sobre la continuidad de la cobertura”, especialmente sobre cómo definirla. Sospecha que el aparente aumento en disputas de contratos entre aseguradoras y proveedores se deriva de las regulaciones sobre la transparencia de los precios hospitalarios, que entraron en vigencia en 2022 y han permitido a los hospitales comparar tasas de reembolso entre sí.
De hecho, el Mount Sinai dijo que exigía un mejor reembolso de UnitedHealthcare porque descubrió que estaba recibiendo pagos considerablemente más bajos que otras “instituciones similares”.
Muchas aseguradoras dicen que continuarán pagando por un período después de que termine un contrato —en general de entre 60 a 90 días— o para completar un “episodio de atención” particular, como un embarazo.
Pero, por ejemplo, con el cáncer, ¿eso significaría una ronda de quimioterapia o el curso completo de un tratamiento, que podría durar muchos años? ¿Es continuidad de cobertura si un paciente debe cambiar de oncólogo en medio de una terapia, o si tiene que dejar a un terapeuta eficaz?
Erin Moses, que trabaja para una pequeña organización sin fines de lucro, encontró a un nuevo terapeuta que le gustó después que ella y su esposo se mudaron a la Costa Central de California en febrero del año pasado. En septiembre, recibió una factura de la práctica que decía que había terminado su contrato con Anthem porque la aseguradora era lenta con sus reembolsos. Esto la dejó con una factura de $814.
“No es que no pudiéramos pagarlo, pero mi esposo y yo estamos tratando de ahorrar para una casa, y eso es mucho dinero”, dijo.
A menudo, a los pacientes los toma desprevenidos, sin saber qué hacer. Cuando Laura Alley se cayó de una escalera en septiembre de 2020 y necesitó cirugía para reparar su pelvis quebrada, el hospital y el cirujano estaban en la red.
Alley escribió al proyecto “Bill of the Month” de KFF Health News y NPR y dijo: “Lo que no podía saber de ninguna manera era que el grupo que proporcionaba la anestesia estaba en disputa con el proveedor de seguros de nuestra firma, y que desde el 30 de julio de 2020, ya no estaban en la red”.
Se sintió “como un títere”, dijo. “Mientras trabajo para recuperarme de una lesión traumática, estoy atrapada en medio de una disputa entre una enorme compañía de seguros y un gran grupo de médicos”.
Alley es dueña de una pequeña firma de arquitectura con su esposo, y terminaron pagando “casi $10,000” por servicios de anestesia fuera de la red. (Este tipo de factura fuera de la red para el paciente ahora estaría prohibido por el No Surprises Act, vigente desde 2022).
Nada de esto será noticia para Feldman, la paciente del Mount Sinai que fue una inocente espectadora en la disputa del sistema hospitalario con Oxford Health Plans. Los padres de Feldman la llamaron recientemente, diciendo que recibieron una carta de su aseguradora, Anthem, diciendo que el 1 de mayo podría terminar su contrato con el Hospital NewYork-Presbyterian, en donde la madrastra de Feldman recibe tratamiento por un cáncer de mama.
Es malo para la salud —y para la cordura— de los pacientes que las promesas percibidas de atención en sus planes de seguro puedan desaparecer repentinamente a mitad de año. Y los reguladores pueden hacer algo al respecto: obligar a los proveedores y aseguradoras a mantener sus contratos entre sí durante todo el término de las pólizas de los pacientes, para que ninguno quedé atrapado en una guerra con la que no tienen nada que ver.
KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF—an independent source of health policy research, polling, and journalism. Learn more about KFF.
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1 year 1 month ago
Health Care Costs, Health Industry, Insurance, Noticias En Español, Hospitals, Insurers
Medical News, Health News Latest, Medical News Today - Medical Dialogues |
Guidewire during TAVR procedures appears to be efficacious and safe: Study
In a recent study, the SavvyWire, a 0.035-inch pre-shaped guidewire with unique pacing properties and a distal pressure sensor, has demonstrated remarkable efficacy and safety during transcatheter aortic valve replacement (TAVR) procedures.
The study, conducted across eight European centers, aimed to assess the device's performance and safety in patients with severe aortic stenosis undergoing TAVR. This study was published in the journal JACC: Cardiovascular Interventions by Ander R. and colleagues.
Continuous hemodynamic pressure monitoring is crucial during TAVR procedures, and the SavvyWire takes innovation to the next level by combining this feature with dedicated pacing properties. This prospective multicenter study delves into the device's ability to achieve effective left ventricular rapid pacing runs and maintain safety throughout the procedure.
This prospective, multicenter clinical study enrolled 121 patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) across eight European centers. The participants, with a mean age of 82.2 ± 5.9 years and 50% women, were included in the study, with 119 ultimately treated with the SavvyWire. The primary efficacy endpoint focused on the device's ability to induce effective left ventricular rapid pacing runs resulting in a significant systemic pressure drop below 60 mm Hg.
Key Findings:
• High Efficacy: The primary efficacy endpoint was achieved in 98.3% of patients, showcasing the SavvyWire's effectiveness in left ventricular rapid pacing runs.
• Mean aortic systolic arterial pressure during rapid pacing: 46.6 ± 11.3 mm Hg.
• Hemodynamic assessment with OptoMonitor 3 achieved in 99.2% of patients.
• Safety First: The safety endpoint was achieved in 99.2% of patients, with no reported procedural mortality, stroke, or ventricular perforation.
• Procedural Insights: The SavvyWire's use could minimize interventions during TAVR procedures, offering significant systemic pressure drops and aiding in clinical decision-making post-transcatheter heart valve deployment.
The SavvyWire has emerged as a reliable and safe tool for TAVR procedures, demonstrating high efficacy in achieving effective left ventricular rapid pacing runs. This pioneering device not only enhances patient safety but also optimizes procedural outcomes, positioning itself as a valuable asset in the realm of transcatheter aortic valve replacement.
Reference:
Regueiro, A., Alperi, A., Vilalta, V., Asmarats, L., Baz, J. A., Nombela-Franco, L., Calabuig, A., Muñoz-García, A., Sabaté, M., Moris, C., Picard-Deland, M., Pelletier-Beaumont, E., & Rodés-Cabau, J. Safety and efficacy of TAVR with a pressure sensor and pacing guidewire. JACC. Cardiovascular Interventions,2023;16(24):3016–3023. https://doi.org/10.1016/j.jcin.2023.10.035
1 year 1 month ago
Cardiology-CTVS,Cardiology & CTVS News,Top Medical News,Latest Medical News
Medical News, Health News Latest, Medical News Today - Medical Dialogues |
Addressing Food Cravings: Causes And Effective Management - Dt Preeti Nagar
Most of us have cravings for foods, ideally to be consumed immediately. That should be greasy, salty, sweet, spicy, crunchy, or crispy, but we are left with nothing to eat. We should always try to eat nutritious food to stop our food cravings or to fulfil the urge for food cravings. We must know the cause of the cravings.
The cravings are caused by various factors that may include nutritional deficiencies, hormonal fluctuations, emotional states, environmental cues, or blood sugar fluctuations.
Sometimes, the body craves certain foods because they lack specific nutrients or due to changes in hormones due to the menstrual cycle or pregnancy, which can lead to cravings. Anxiety, frustration, sorrow and even joy can cause food cravings. Low blood sugar levels can result in cravings for sugary foods or carbohydrates.
A question arises about how we can deal with these cravings. Food cravings require focusing on balance, nutrient-dense foods, and mindful eating. Your meal should always contain a variety of protein sources, good fats, fiber-rich carbohydrates, fruits, and vegetables.
This equilibrium lessens the chance of cravings by helping to maintain blood sugar levels and prolonging feelings of satisfaction. To deal with food cravings, mindful eating with healthy snacks and adequate sleep might help to stay stress-free and hydrated, leading to reduced cravings.
While it is obvious that some foods might make us want more, it is less if food can become an addiction, just like drugs and alcohol. So, we should always keep an eye on what we intake or crave.
When we don’t follow a good diet, this can lead to stress, less sleep, and laziness. You run the danger of overeating if you put off eating because you are busy or distracted. Eating later will just make you more hungry. So always try to eat healthy food on time.
Try to be hydrated and drink plenty of water throughout the day. Sometimes, dehydration is confused with hunger. Intake of water or herbal teas might also help reduce unwanted cravings. Whenever you are craving junk food, try to avoid it or replace it with fruits or something healthy. Fruits not only keep you healthy but also increase protein and fibre in your body.
You should always pay attention to your hunger and fullness cues and practice mindful eating by focusing on enjoying your food. Avoid distractions while eating to prevent thoughtless overeating.
Include healthy fats in your meals, like watermelon, bananas, whole grains, nuts, seeds, legumes, etc. Healthy fats provide satiety and contribute to overall satisfaction with meals. You should prioritize fibre in your meals. Meats, poultry, fish, eggs, tofu, and dairy products are great sources of rich protein that help you control your appetite and cravings by promoting a feeling of fullness.
Food cravings are common and can be hard to ignore, leading to consuming excessive amounts of calories, poor nutrients and junk food like cake, ice cream, etc. You should avoid unhealthy food and go for something healthy and nutritious that gives you energy and keeps you healthy to control your food cravings.
Food cravings are normal, but if you find yourself more engaged with your cravings than regular ones, then it can be harmful, and you must consult with the doctor.
Disclaimer: The views expressed in this article are of the author and not of Medical Dialogues. The Editorial/Content team of Medical Dialogues has not contributed to the writing/editing/packaging of this article.
1 year 1 month ago
Health Dialogues,Diet and Nutrition
STAT+: As Humira biosimilars take over the market, CVS has created a new ploy: the drug ‘rebate credit’
The biggest enticement that large pharmacy benefit managers offer to the employers that hire them is drug rebates — a steady stream of money sent back to their clients, a tangible symbol of the discounts that PBMs are able to wrangle out of pharmaceutical companies.
PBMs, the middlemen of drug pricing negotiations, also claim portions of those lucrative rebates for themselves. So when new market developments threaten to diminish or wipe away that revenue stream, PBMs find crafty ways to keep as much of those dollars as possible — often at the expense of employers.
One such case occurred last year, when a wave of Humira biosimilars entered the market and drug companies slashed the list prices of their insulin products. CVS Caremark, the PBM owned by CVS Health that oversees the prescription drug benefits of 103 million people, told its employer clients that it anticipated “more lower-cost products (including specialty biosimilars) may become preferred products” on its lists of approved drugs for 2024, according to documents obtained by STAT.
1 year 1 month ago
Business, Exclusive, health insurance, life sciences, PBMs, Pharmaceuticals, STAT+
Health Archives - Barbados Today
Fogging schedule for March 18 – 22
The Vector Control Unit of the Ministry of Health and Wellness will take the fight against mosquito-borne illnesses to three parishes this week – St Lucy, St Peter, and St James.
The team will fog districts in St Lucy on Monday, March 18, including Crab Hill No. 2, Content, Long Gap, Coles Cave Road, Grape Hall, Archers Bay, and Salmond.
The Vector Control Unit of the Ministry of Health and Wellness will take the fight against mosquito-borne illnesses to three parishes this week – St Lucy, St Peter, and St James.
The team will fog districts in St Lucy on Monday, March 18, including Crab Hill No. 2, Content, Long Gap, Coles Cave Road, Grape Hall, Archers Bay, and Salmond.
The following day, Tuesday, March 19, they will return to that parish and visit Durham, Mount View Road, Rock Hall Road, Jemmotts, Mount Gay, Alexandra, Josey Hill, Nestfield, and Pickerings.
The Unit will then take its mosquito eradication efforts to St Peter, on Wednesday, March 20, when Graveyard, Date Tree Hill, Boscobel, Collins, Diamond Corner, Moore Hill, Castle, Gays, and surrounding areas will be sprayed.
On Thursday, March 21, and Friday, March 22, the parish of St James will be targeted. On Thursday, the team will go into Upper Mount Standfast, Weston, Taylor Gap, Fox Club Road, Reid Gap, Pineapple Avenue, Prescod Road, Husband Road, The Garden, and Store House Road.
The fogging exercise for the week will conclude on Friday, in the following communities: Store House Road, Haynes View Close, Patanne Gardens, Willow Heights Drive, Pavilion Grove, Glitter Bay Terrace, Ince Walk, Mango Drive, Heron Court, Trent’s Tenantry, and Jamestown Park.
Fogging takes place from 4:30 to 8:30 p.m. daily. Householders are reminded to open their windows and doors to allow the spray to enter. Children should not be allowed to play in the fog.
Members of the public are advised that the completion of scheduled fogging activities may be affected by events beyond the Unit’s control. In such circumstances, the Unit will return to communities affected in the soonest possible time.
(BGIS)
The post Fogging schedule for March 18 – 22 appeared first on Barbados Today.
1 year 1 month ago
Health, Local News