STAT

STAT+: Pharmalittle: We’re reading about Zantac court cases, a Neurocrine schizophrenia pill, and more

Hello, everyone, and how are you today? We are doing just fine, thank you, especially since the middle of the week is upon us. After all, we have made it this far, so we are determined to hang on for another couple of days. And why not? The alternatives — at least those we can identify — are not so appetizing. And what better way to make the time fly than to keep busy.

So grab that cup of stimulation and get started. Our flavor today is pumpkin spice, for those tracking our habits. Now, though, the time has come to get busy. So please grab your own cup and dig in to the items of interest assembled below. We hope you have a wonderful day, and please do keep in touch. …

Delaware’s highest court agreed to hear an appeal by GSK and other drugmakers seeking to end more than 70,000 lawsuits claiming discontinued heartburn drug Zantac caused cancer, Reuters writes. GSK, Pfizer, Sanofi, and Boehringer Ingelheim are asking the court to overturn an order by a lower court judge allowing plaintiffs in the lawsuits to offer expert testimony on the alleged cancer link, which the companies argue is not supported by sound scientific methods. Without that testimony, the lawsuits cannot go forward. The drugmakers won a significant victory in 2022, when a federal judge in Florida rejected the plaintiffs’ expert witnesses in about 50,000 cases on the grounds that they did not use reliable scientific methods. Some of the Florida cases are being appealed, and the vast majority of the remaining cases are in Delaware.

Neurocrine Biosciences reported that the lowest dose of an experimental pill for schizophrenia reduced psychosis reported by patients in a mid-stage study, but higher doses of the drug also tested were ineffective, STAT informs us. The company said the study results supported advancing the medicine into Phase 3 studies next year. Investors viewed the mixed data with more concern, sending Neurocrine stock down 18% in early trading. The drug belongs to an emerging class of neuropsychiatric medicines that target muscarinic receptors in the brain. This type of drug has garnered a lot of attention due to the acquisitions of Karuna Therapeutics ($14 billion) and Cerevel Therapeutics ($8.7 billion) by Bristol Myers Squibb and AbbVie, respectively.

Continue to STAT+ to read the full story…

1 year 2 months ago

Pharma, Pharmalot, pharmalittle, STAT+

Health – Dominican Today

HOMS successfully completes awake brain surgery

Santiago, DR.- The Metropolitan Hospital of Santiago (HOMS) recently performed its first awake brain tumor surgery, demonstrating that Dominican neurological medicine is on par with that of developed countries. This specialized technique underscores HOMS’ dedication to delivering advanced medical solutions focused on patient safety and well-being.

Santiago, DR.- The Metropolitan Hospital of Santiago (HOMS) recently performed its first awake brain tumor surgery, demonstrating that Dominican neurological medicine is on par with that of developed countries. This specialized technique underscores HOMS’ dedication to delivering advanced medical solutions focused on patient safety and well-being.

The procedure was led by neurosurgeon Dr. Francisco Matos Ureña, who emphasized the benefits of this approach, including minimal bone removal and reduced risk of damage to surrounding brain tissue, thereby preserving the patient’s quality of life. Prior to the surgery, the 36-year-old patient, who had a tumor in a critical brain area affecting speech, comprehension, and movement, underwent thorough psychological, neuropsychological, and neurophysiological evaluations.

Awake brain surgery is often used for treating certain neurological conditions, such as tumors or epilepsy, especially when the tumor is located near areas critical to speech and motor functions. Keeping the patient conscious allows the surgical team to monitor cognitive functions in real time, reducing the risk of impairing essential abilities. This milestone procedure represents a significant advancement in neurosurgery at HOMS, offering a safer alternative to traditional methods that carry a higher risk of motor function loss.

1 year 2 months ago

Health, brain tumor surgery, Dominican Republic, Homs, Santiago

Health Archives - Barbados Today

QEH on track to revolutionise cancer care with linear accelerator

In a major leap forward for cancer care on the island, the Queen Elizabeth Hospital (QEH) has inched closer to introducing cutting-edge radiotherapy treatment with the installation of a state-of-the-art linear accelerator.

This advanced technology promises to revolutionise cancer treatment, offering patients more precise, effective, and potentially life-saving care, according to Paula Agbowu, the hospital’s director of engineering services.

“Coming up is the acquisition of a linear accelerator machine that will be used to help treat some of our oncology cases,” Christine Greenidge, the hospital’s chief operating officer, said during this week’s Pulse Radio programme.

The new linear accelerator, expected to be operational by year’s end, represents a significant upgrade from the hospital’s current cobalt-based technology. It will enable oncologists to deliver highly targeted radiation therapy, potentially improving outcomes and reducing side effects for cancer patients, according to Agbowu.

The director of engineering services highlighted the transformative impact this acquisition will have on patient care.

“The actual linear accelerator will mean that the kind of treatment that we will be able to afford our patients will be much more enhanced than the treatment that we had before,” she stated. “This is an upgrade and a step up from what we had in place before.”

The installation of this sophisticated equipment is part of a broader £130 million investment in the hospital’s infrastructure and technology. This substantial funding, announced earlier this year by the Ministry of Health, underscores the government’s commitment to enhancing healthcare services across the island. The first tranche of funding is expected to be released in the coming weeks, Agbowu revealed.

The hospital is undertaking comprehensive infrastructure improvements, including modifications to the treatment bunker, electrical systems, and IT infrastructure. Crucially, the QEH is investing in its staff to ensure they can maximise the potential of this new technology. Physicists, radiographers, and oncologists are already engaged in intensive training programmes to familiarise themselves with the linear accelerator’s advanced capabilities.

Meanwhile, the QEH is undertaking an ambitious initiative to transform healthcare delivery, making it more accessible and efficient for patients.

At the heart of this overhaul is an expansion of telehealth services, allowing remote monitoring of patients with chronic conditions such as congestive heart failure. This innovative approach enables medical staff to track vital signs from patients’ homes, reducing the need for frequent hospital visits and allowing for timely interventions.

QEH is also transitioning to electronic medical records, streamlining appointment management and granting patients easier access to their health information. The comprehensive upgrade extends to health information systems, enhancing both patient care and data protection. These initiatives are part of the $130 million capital expenditure programme designed to acquire new technology and upgrade existing systems at the hospital.

The post QEH on track to revolutionise cancer care with linear accelerator appeared first on Barbados Today.

1 year 2 months ago

Health, Local News

Health Archives - Barbados Today

Minister warns of rising obesity crisis as school year nears

With less than three weeks until the new school year, Minister of State in the Ministry of Health and Wellness Davidson Ishmael has issued a stark warning about Barbados’ escalating health crisis, driven by rising rates of childhood obesity and non-communicable diseases (NCDs).

The minister highlighted the urgency of tackling childhood obesity by sharing a personal observation: “I passed a young child today—he couldn’t have been more than four years old—walking with his mother, and I must say, this young boy was probably close to my weight as an adult male. If that trend continues, I’m not sure if he’s going to become one of those very productive citizens that we want.”

He cautioned that the growing burden of treating obesity and other health conditions threatens the country’s development by diverting critical financial resources away from progress.

Ishmael was speaking at the Heart and Stroke Foundation of Barbados’ vendor training session on the updated School Nutrition Policy at Lingwood Hall at St Ann’s Fort, the Barbados Defence Force headquarters. He highlighted the economic impact of the health crisis.

“If we have to redirect funds and use those funds continually to treat ill health, then you can see how we can actually be hampering our development as a country,” he said. The minister warned that such redirection could hinder the nation’s growth in other essential areas, jeopardising long-term sustainability.

Ishmael drew a direct connection between the rise in NCDs and the growing rates of childhood obesity, a trend he said must be reversed.

“We can see that many of our young people are carrying a little bit more weight than they should,” he noted. The minister explained that obesity in childhood could lead to long-term health problems, saying, “When a person is overweight or obese, it can lead them to a long-term lifestyle that unfortunately results in the development of NCDs, such as diabetes, hypertension, cardiovascular disease, cancers, etc.”

To combat this public health challenge, the government is crafting a comprehensive national nutrition policy designed to improve the overall health of all Barbadians. Ishmael revealed that the Ministry of Health and Wellness, in partnership with the Ministry of Education, is working to expand the existing school nutrition policy into a nationwide initiative.

“We are in the process of developing a national nutrition policy that will go beyond only schools and ensure that all Barbadians understand the importance of consuming nutritious and healthy meals,” he said.

Vendors and concessionaires, who play a crucial role in shaping eating habits, are key to the success of this initiative, said Ishmael, even as he acknowledged their concerns, particularly over potential impacts on sales.

The minister encouraged the food sellers to embrace healthier options.

“There is a natural fear among vendors and concessionaires,” he said. “But I’m glad to hear from the Heart and Stroke Foundation and other NGOs that we’re working to help you find alternatives. And there are always alternatives.”

Ishmael said a “frank conversation” on obesity was needed.

“We have a problem with childhood obesity in our country and obesity in general,” he said. “We have a problem with NCDs and the management of NCDs in our country. We have a problem with the financial burden that it takes to address ill health. We have a problem. Now that we’ve noted that, we’re having a frank conversation about how to solve it.”

The minister reaffirmed his commitment to addressing the health crisis and urged all citizens to join in the effort.

“The future of our country depends on ensuring that we have healthy young people today,” he said. “You have the full support of the Ministry of Health and Wellness. You have my full support personally.”

The post Minister warns of rising obesity crisis as school year nears appeared first on Barbados Today.

1 year 2 months ago

Education, Health, Local News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

USFDA nod to Lupin Brimonidine Tartrate Ophthalmic Solution

Mumbai: Global pharma major Lupin Limited has announced that the Company has received approval from the United States Food and Drug Administration (U.S. FDA) for its Abbreviated New Drug Application for Brimonidine Tartrate Ophthalmic Solution, 0.1%.

The product is a generic equivalent of Alphagan P Ophthalmic Solution, 0.1%, of AbbVie Inc. It will be manufactured at Lupin's Pithampur facility in India.

Brimonidine Tartrate Ophthalmic Solution, 0.1% is an alpha adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Read also: Lupin alliance partner ForDoz gets USFDA nod for Doxorubicin Hydrochloride Liposome Injection

Open-Angle Glaucoma is the most common form of glaucoma, a group of eye conditions that damage the optic nerve, leading to vision loss. This damage is often caused by abnormally high pressure in the eye (intraocular pressure), though normal-pressure glaucoma can also occur.

Medical Dialogues team had earlier reported that Lupin Limited had received USFDA nod for its Abbreviated New Drug Application for Travoprost Ophthalmic Solution USP, 0.004%(Ionic Buffered Solution). Travoprost Ophthalmic Solution USP, 0.004%, is indicated for the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension.

Read also: Lupin bags USFDA nod for Travoprost Ophthalmic Solution

Brimonidine Tartrate Ophthalmic Solution (RLD Alphagan P) had an estimated annual sales of USD178.5 million in the U.S. (IQVIA MAT June 2024).

Lupin Limited is a global pharmaceutical Company headquartered in Mumbai, India, with products distributed in over 100 markets. Lupin specializes in pharmaceutical products, including branded and generic formulations, complex generics, biotechnology products, and active pharmaceutical ingredients. The company has a presence in India and the U.S. across multiple therapy areas, including respiratory, cardiovascular, anti-diabetic, anti-infective, gastrointestinal, central nervous system, and women’s health. Lupin has 15 state-of-the-art manufacturing sites and 7 research centers globally.

Also Read:6 medicines of Alembic Pharma received USFDA nod during Q2FY24

1 year 2 months ago

News,Medicine,Ophthalmology,Medicine News,Ophthalmology News,Industry,Pharma News,Latest Industry News

Health

Keeping kids’ eyes safe from blue light

As parents, we understand the importance of protecting our children’s eyes from the sun’s harmful rays, but what about the harmful effects of blue light? Blue light, a colour in the visible light spectrum, is everywhere. Believe it or not, sunlight...

As parents, we understand the importance of protecting our children’s eyes from the sun’s harmful rays, but what about the harmful effects of blue light? Blue light, a colour in the visible light spectrum, is everywhere. Believe it or not, sunlight...

1 year 2 months ago

Health

The benefits of papaya

Papaya has long been regarded as containing healing properties, as both the fruit and its leaves are used in traditional medicinal practices across the world. While more studies must be conducted to determine the benefits of papaya leaves, modern...

Papaya has long been regarded as containing healing properties, as both the fruit and its leaves are used in traditional medicinal practices across the world. While more studies must be conducted to determine the benefits of papaya leaves, modern...

1 year 2 months ago

Health

Mpox is back

Monkeypox is caused by the Orthopoxvirus, which is related to the smallpox family of disorders native to the African continent. However, this virus has recently spread throughout Africa and to some countries in Europe. Monkeypox (mpox)is capable...

Monkeypox is caused by the Orthopoxvirus, which is related to the smallpox family of disorders native to the African continent. However, this virus has recently spread throughout Africa and to some countries in Europe. Monkeypox (mpox)is capable...

1 year 2 months ago

The Medical News

Deep learning reveals disparities in brain aging across Latin America and the Caribbean

Study reveals that socioeconomic inequality, pollution, and health disparities significantly contribute to brain-age gaps, with Latin American and Caribbean populations, especially women and those with cognitive impairments, being most affected.

Study reveals that socioeconomic inequality, pollution, and health disparities significantly contribute to brain-age gaps, with Latin American and Caribbean populations, especially women and those with cognitive impairments, being most affected.

1 year 2 months ago

Healio News

VIDEO: Create a strong network of advocates through ‘mosaic mentoring’

CARLSBAD, Calif.

— In this Healio Video Perspective from the Women in Ophthalmology Summer Symposium, Tara Capalbo of AbbVie discusses the power of “mosaic mentoring” in creating a strong support system as a leader.According to Capaldo, mosaic mentoring entails “creating your own personal think tank around all of the folks that can help support you, and that you can support in your journey.”This method can help build a network of advocates and sponsors to support leaders even when they are not in the room, she said.

1 year 2 months ago

Health | NOW Grenada

Foods that boost mood and brain health 

“Eating at least one well-balanced meal each day can go a long way in ensuring that you get the right amount of nutrients and minerals your body needs to function”

View the full post Foods that boost mood and brain health  on NOW Grenada.

“Eating at least one well-balanced meal each day can go a long way in ensuring that you get the right amount of nutrients and minerals your body needs to function”

View the full post Foods that boost mood and brain health  on NOW Grenada.

1 year 2 months ago

Health, PRESS RELEASE, brain health, gfnc, grenada food and nutrition council

STAT

STAT+: Pharmalittle: We’re reading about Lilly cutting Zepbound’s price; Pfizer selling direct to consumers, and more

Good morning, everyone, and how are you today? We are just fine, thank you, especially since clear, blue skies and a slightly cool breeze are enveloping the Pharmalot campus this morning. To celebrate, we have given the official mascots new treats and are treating ourselves to a joyful cup of stimulation. Our choice today is pecan pie — sweets for the sweet, you know.

Meanwhile, here are a few items of interest to get you started on your journey, which we hope will be meaningful and productive. Best of luck, and do keep in touch. …

Eli Lilly will start providing low-dose vials of its obesity drug Zepbound through its direct-to-consumer platform, a move that will likely ease supply constraints and draw more patients to the company’s online portal, STAT writes. Lilly is also selling the vials at a discount to the currently available injectable pens, which carry a list price of $1,060 for a month’s supply. Under the new offering, which is meant for patients paying on their own without insurance, 2.5-milligram vials will cost $399 for one month’s supply, and 5-milligram vials will cost $549, roughly the equivalent of the average monthly payment for a used car. Dosages of Zepbound pens go up to 10 and 15 milligrams, but Lilly is only offering low-dose vials for now and will evaluate the possibility of selling high-dose vials later.

Cigna plans to remove AbbVie’s blockbuster rheumatoid arthritis drug Humira from some of its lists of preferred drugs for reimbursement in 2025, and recommend less-pricey biosimilar versions of the medicine instead, Reuters tells us. Going forward, Boehringer Ingelheim’s Cyltezo, Simlandi from Teva Pharmaceuticals and Alvotech, and an unbranded version of Hyrimoz from Sandoz will be covered on some lists that are managed by its pharmacy benefits unit Express Scripts. This is the second major U.S. pharmacy benefits manager to stop recommending coverage of Humira, following similar action by CVS Health’s Caremark unit in April. That move led more patients to switch to biosimilar versions of Humira in three weeks than had in the prior 15 months.

Continue to STAT+ to read the full story…

1 year 2 months ago

Pharma, Pharmalot, pharmalittle, STAT+

Health Archives - Barbados Today

New HCC head tackles Caribbean’s ‘deadly triad’

The new boss of the Healthy Caribbean Coalition (HCC) has unveiled an ambitious strategy to combat the “deadly triad” of cardiovascular disease, climate change and “commercial determinants of health” which threaten the Caribbean region.

Dr Kenneth Connell, the deputy dean of recruitment and outreach in the faculty of medical sciences at the University of the West Indies Cave Hill Campus, has been appointed as the president of the HCC, a not-for-profit Caribbean non-communicable disease (NCD) alliance of over 100 health and non-health civil society organisations, whose vision is to reduce death and disability from chronic diseases among Caribbean people.

In his first address as HCC president, Dr Connell outlined a multi-pronged approach to improve public health across the Caribbean. “Small island states are now under attack from the deadly triad of cardiovascular disease, climate change, and commercial determinants of health. The HCC must now position itself to be innovative, culturally sensitive, and very responsive to the needs of our stakeholders, especially the individual citizens of our one Caribbean community,” he stated.

At the heart of Dr Connell’s plan is a push for robust school nutrition policies. These aim to instill healthy eating habits in young people, potentially stemming the rise of obesity and related NCDs. Alongside this, he proposes the introduction of octagonal front-of-package warning labels on food products, a measure that has shown promise in other parts of the world in guiding consumers towards healthier choices.

The new president, also a consultant physician at the Queen Elizabeth Hospital and consultant-in-charge of the hospital’s resistant hypertension clinic, is also setting his sights on the food industry, with a particular focus on eliminating trans fatty acids from ultra-processed foods. This initiative could significantly reduce the risk of heart disease across the Caribbean.

“I am both passionate, and unconditionally committed, to advancing our region as a model health space for the world,” he said.

The insurance company Sagicor, which has had a longstanding partnership with the HCC, has welcomed the plan by the new president.

“Sagicor looks forward to future collaborations with the HCC as we seek to help our communities improve the management of chronic diseases in our region,” Paul Inniss, executive vice president of Sagicor Life Inc (Barbados), said.

(PR)

The post New HCC head tackles Caribbean’s ‘deadly triad’ appeared first on Barbados Today.

1 year 2 months ago

Health, Local News

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