Healio News

First patient dosed in phase 2 trial of EC-104 implant for diabetic macular edema

Eclipse Life Sciences has enrolled and dosed the first patient in the BETTIS-1 phase 2 clinical trial investigating the EC-104 implant for the treatment of diabetic macular edema, according to a press release.The randomized, controlled, double-masked trial will compare the extended release of 0.14 mg and 0.092 mg doses of EC-104 (fluocinolone acetonide) with Ozurdex (dexamethasone intravitreal

implant, AbbVie) in patients with DME who had a previous suboptimal clinical response to intravitreal anti-VEGF therapy. Enrolled patients have also previously been treated with locally administered

8 months 1 week ago

STAT

STAT+: Meet the billionaire media mogul who’s taking on the food industry

WASHINGTON — The idea for Todd Wagner’s new advocacy organization FoodFight USA, he says, came to him after visiting George Clooney in Lake Como. He’s recruited Morgan Freeman, who is “obviously” a friend. He personally lobbied Arnold Schwarzenegger and current California Gov.

Gavin Newsom to support food makers’ nightmare scenario — a first-in-the-nation law banning certain food additives in the state, which was signed into law last year.

Wagner is best known for his co-ownership of Magnolia Pictures alongside his longtime business partner Mark Cuban. But now, he told STAT in an extended interview, he’s dedicating himself to fighting food makers and their industrial creations, ultra-processed foods.

“I want people angry,” said Wagner, who is worth an estimated $1.9 billion. “This is an indictment of the food companies that have tainted our food supply, and now we wake up 50, 60 years later with a nation that is unhealthy.”

Continue to STAT+ to read the full story…

8 months 1 week ago

Politics, FDA, Nutrition, STAT+, States

Health News Today on Fox News

'Zika-like' mosquito-borne virus has spread into Europe, health officials warn

Cases of the Oropouche virus (OROV) emerging in Europe have health officials on high alert.

As of the end of July, 19 cases had been reported with 12 in Spain, five in Italy and two in Germany, per the European Centre for Disease Prevention and Control.

Cases of the Oropouche virus (OROV) emerging in Europe have health officials on high alert.

As of the end of July, 19 cases had been reported with 12 in Spain, five in Italy and two in Germany, per the European Centre for Disease Prevention and Control.

The disease is typically spread through bites from mosquitoes and midges (small flies, particularly the Culicoides paraensis species), according to the U.S. Centers for Disease Control and Prevention (CDC).

WEST NILE DEATH REPORTED IN TEXAS AS HEALTH OFFICIALS WARN RESIDENTS TO SAFEGUARD AGAINST MOSQUITOES

Since first emerging in Trinidad and Tobago in 1955, the Oropouche virus has had "limited circulation" in regions of South America, particularly in forested areas.

Three-toed sloths and birds have been identified as "natural reservoirs" for Oropouche, which means they act as hosts of the disease.

"The virus doesn't spread from person to person," Dr. Marc Siegel, senior medical analyst for Fox News and clinical professor of medicine at NYU Langone Medical Center, confirmed to Fox News Digital.

TIGER MOSQUITOES BLAMED FOR SPREAD OF DENGUE FEVER: ‘MOST INVASIVE SPECIES’

On Aug. 1, the Pan American Health Organization (PAHO) issued an epidemiological alert urging countries to "strengthen surveillance and implement laboratory diagnosis for the identification and characterization of cases … potentially associated with OROV infection."

By the end of July, there were 8,078 confirmed cases of Oropouche virus in five countries, including Bolivia (356), Brazil (7,284, with two deaths), Colombia (74), Cuba (74) and Peru (290), as reported by the PAHO.

"Experts fear that if the current outbreak of Oropouche fever expands further, it could overwhelm South America's already stretched health care system," according to an article published in The Lancet Infectious Diseases on Aug. 8.

The PAHO’s alert also warned of cases of the virus in Brazil that were transmitted from pregnant women to their fetuses in Brazil.

IN A POTENTIAL OUTBREAK, IS BIRD FLU TESTING AVAILABLE FOR HUMANS? WHAT TO KNOW

"These cases are under investigation," the CDC stated on its website, noting that the agency is working with PAHO and "other international partners" to assess potential risks the virus presents during pregnancy.

Siegel said, "There is some risk to the fetus in terms of birth defects."

OROV, which is classified as an arbovirus, is often mistaken for other similar viruses, like Zika, dengue, chikungunya and malaria, according to the CDC.

Symptoms of the virus include fever, headache, muscle aches, stiff joints and chills.

Some may develop a rash that begins on the torso and spreads to other body parts.

Symptoms usually begin within four to eight days of being bitten, and last for three to six days.

"Symptoms can abate and reoccur," Siegel noted.

In severe cases, patients may develop meningitis, encephalitis or other "neuroinvasive" diseases, the CDC stated.

For more Health articles, visit www.foxnews/health

For those patients, symptoms can include intense headaches, dizziness, confusion, nausea, vomiting, light sensitivity, lethargy, stiff neck and involuntary eye movements

"Around 4% of patients develop [neurologic symptoms] after the first febrile illness," Siegel said.

Most people who contract Oropouche will recover on their own without any long-term effects, the CDC stated.

"There are no vaccines for prevention and no treatments," Siegel said.

The best means of prevention is to avoid bites from midges and mosquitoes, according to experts.

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"People are advised to take preventive measures, including the use of repellents, clothing that covers legs and arms, and fine mesh mosquito nets, and to take extra precautions during outbreaks, particularly for vulnerable groups such as pregnant women," the PAHO advised in its alert.

Supportive care can include rest, fluids and medications to reduce fever and alleviate pain.

"Patients who develop more severe symptoms should be hospitalized for close observation and supportive treatment," the agency stated.

There have been "very few" deaths reported from Oropouche, the CDC noted.

Those who are experiencing symptoms and have risk factors can contact their local health department for testing.

"Clinicians in these areas where importation has occurred may not be familiar with this infection and need to be alert to its possibility," Dr. Amesh Adalja, M.D., an infectious disease expert at the Johns Hopkins Center for Health Security in Baltimore, told Fox News Digital.

Fox News Digital reached out to the CDC for comment.

8 months 1 week ago

Health, viruses, infectious-disease, insects, lifestyle, outbreaks

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

Aurobindo Pharma net profit increases 61 percent to Rs 919 crore in Q1

New Delhi: Aurobindo Pharma has announced a 61 percent year-on-year increase in its consolidated net profit for the first quarter ended June 2024. The Hyderabad-based pharmaceutical company reported a net profit of Rs 919 crore, up from Rs 571 crore during the same period last year.

In a release, Aurobindo Pharma highlighted that its revenue from operations also saw a significant boost, climbing to Rs 7,567 crore in the June quarter compared to Rs 6,851 crore in the corresponding quarter of the previous fiscal year. 

Commenting on the Company’s performance, Mr. K. Nithyananda Reddy, Vice-Chairman and Managing Director of the Company said: “We are pleased with our continued strong performance this quarter, with a significant top-line growth across all our business segments. Our profitability was sustained by improved gross margins and operational efficiencies, while ramping-up our recently commercialized plants. We are confident in our ability to achieve our growth targets for FY25.” 

US formulations (excluding Puerto Rico) revenue increased by 13.3% YoY to INR 3,555 Cr (USD 426 million). Europe formulations revenue increased by 7.9% YoY to INR 1,982 Cr (EUR 221 million)

Whereas, Growth Markets revenue increased by 49.2% YoY to INR 709 Cr (USD 85 million).

Read also: Aurobindo Pharma secures USFDA okay for generic version of Novo Nordisk Vagifem

Aurobindo Pharma Limited is an integrated global pharmaceutical company headquartered in Hyderabad, India. The Company develops, manufactures, and commercializes a wide range of generic pharmaceuticals, branded specialty pharmaceuticals and  active pharmaceutical ingredients globally in over 150 countries.

The company has 29 manufacturing and packaging facilities that are approved by regulatory agencies including USFDA, UK MHRA, EDQM, Japan PMDA, WHO, Health Canada, South Africa MCC, Brazil ANVISA. The Company’s     product portfolio is spread over 7 major therapeutic/product areas encompassing CNS, Anti-Retroviral, CVS, Antibiotics, Gastroenterological, Anti-Diabetics and Anti-Allergic, supported by a strong R&D set-up.

Read also: Aurobindo Pharma arm buys Ace Lab for Rs 17.91 crore

8 months 1 week ago

News,Industry,Pharma News,Latest Industry News

Medical News, Health News Latest, Medical News Today - Medical Dialogues |

PG Medico Murder at RG Kar Medical College: Doctors announce nationwide protest

New Delhi: As doctors across the country have come out on the streets demanding justice for the PG medico who was brutally raped and murdered in the seminar room of RG Kar Medical College, police have come out with the arrest of the prime suspect, Sanjay Roy.

The arrest followed the discovery of a crucial piece of evidence—a Bluetooth device left at the crime scene. This small but vital clue played a pivotal role in leading investigators to Roy. Detailed forensic analysis linked the device to Roy, who had been observed in CCTV footage near the seminar hall around the time of the crime. Roy was arrested on Saturday and was sent to 14-day police custody. He confessed to the crime

As per sources, Sanjay Roy was a civic volunteer. Though officially termed as civic volunteers, many still refer to them as “civic police”, which was originally created in Bengal to assist the police and also a part of a powerful police welfare board. Since he was a civic volunteer, Roy had an easy access in the hospital. He was seen entering the hospital at around 4 am and leaving leaving the premises early on Friday morning. 

The accused was charged under sections 64 (rape) and 103 (murder) of BNS and was produced before Sealdah court, which remanded him to police custody till August 23.

The victim, a 31-year-old doctor, was found deceased in a seminar hall at the hospital on Friday morning. The initial autopsy of the post-graduate trainee doctor indicated that she was murdered after being sexually assaulted. There was bleeding from the woman's private parts, said the report. There were injuries to other parts of the body as well

"This is definitely not a case of suicide; the woman was murdered following sexual assault," a police officer told news agency PTI.

Meanwhile, In response to the incident, junior doctors and students at various state-run hospitals, including RG Kar Medical College, National Medical College, and Medical College, Kolkata, held protest sit-ins and processions. Similar protests also took place at district hospitals such as Bardhaman Medical College and Bankura Sammilani Medical College. Protests and pen-down strikes are being continued in various parts of the country

Maintaining that protests and processions by junior doctors demanding exemplary punishment for the accused and enhanced security at hospitals were justified, the Chief Minister of the state urged the doctors to also carry on giving healthcare services to patients.

West Bengal Chief Minister Mamata Banerjee announced to seek a death penalty for the perpetrator. Her announcement came shortly after the accused, who was reportedly an outsider frequenting the hospital premises, was arrested and later remanded to 14-day police custody.

RG Kar Medical College MS Removed

The West Bengal health department has ordered the removal of Dr. Sanjay Vashisth from his position as medical superintendent-cum-vice principal. Dr. Bulbul Mukhopadhyay, the dean of student affairs, has been appointed to take over Vashisth's responsibilities. Dr. Vashisth has been reassigned as a professor at the National Medical College & Hospital.

Nationwide Shutdown on Monday

Sunday saw a continued protest from doctors from all medical colleges in West Bengal. Protesters at RG Kar Medical College in Kolkata raised safety concerns, citing the absence of CCTV in sensitive areas, tout rackets, inadequate restrooms for on-call doctors, and poor screening of outsiders. 

Meanwhile, resident doctors associations ( RDA) and medical associations across the country are coming in support of Kolkata Doctors. The RDAs of several major hospitals, including VMMC & Safdarjung Hospital, UCMS & GTBH, and ABVIMS & Dr. RML Hospital, have issued statements expressing their outrage and demanding justice. These associations have collectively decided to halt all elective services, including OPDs, elective OTs, and ward duties, while ensuring that emergency services remain operational.

Doctors are demanding Immediate and Impartial Investigation, Enhanced Security for Healthcare Workers, No Police Brutality or Mistreatment of protesting doctors, stating the nationwide strike will continue until these demands are met  

8 months 1 week ago

Editors pick,News,Health news,Doctor News,Notifications

Health Archives - Barbados Today

WHO’s emergency committee to meet August 14 over Mpox

The World Health Organization’s emergency committee will meet next Wednesday to decide whether to trigger its highest alert level over an Mpox outbreak sweeping through several African countries.

The WHO said in a note to journalists that the closed virtual meeting will start at 1000 GMT Wednesday.

The World Health Organization’s emergency committee will meet next Wednesday to decide whether to trigger its highest alert level over an Mpox outbreak sweeping through several African countries.

The WHO said in a note to journalists that the closed virtual meeting will start at 1000 GMT Wednesday.

“The committee will provide me with its views on whether the outbreak constitutes a public health emergency of international concern,” WHO head Tedros Adhanom Ghebreyesus wrote on X.

If that turns out to be the case they will advise on “how to better prevent and reduce the spread of the disease”, he added.

Formerly known as monkeypox, mpox is an infectious disease caused by a virus transmitted to humans by infected animals but can also be passed from human to human through close physical contact.

The disease causes fever, muscle aches and large boil-like skin lesions.

The Democratic Republic of Congo (DRC) is the country currently most affected by the latest outbreak, with 14,479 confirmed and suspected cases by August 3 and 455 deaths, according to the African Union’s health agency.

SOURCE: AFP

The post WHO’s emergency committee to meet August 14 over Mpox appeared first on Barbados Today.

8 months 1 week ago

Health, World

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